CHS CERTIFIED HISTOCOMPATIBILITY
SPECIALIST ACTUAL EXAM 2026 200
COMPLETE QUESTIONS AND ANSWERS
ADVANCED PREPARATION KIT TRUSTED
RESOURCE GRADED A+
⩥ What approach is even better than the correct answer to :Reagent X
arrives in the lab without an expiration date. What action should you
take?=Obtain manufacturer and HLA lab recommendations and derive
an expiration date.
a. Read over the ASHI manual and find published expiration guidelines
b. Buy two bottles of the chemical. Store one, as recommended, at 4C
and the other at RT. When the RT one goes bad you know the 4C is also
bad
c. Periodically QC the reagent and develop a QA analysis of its
performance
d. Employ Google on a monthly schedule to look for reports of adverse
outcomes using older lots of the reagent. Answer: c. Periodically QC the
reagent and develop a QA analysis of its performance
⩥ A supervisor notices that a previously meticulous worker has been
making an inordinate number of mistakes in clinical assays. What
approach should the supervisor take?
,a. Use the power of peer pressure by emailing defamatory reports on the
employee to co-workers
b. Meet with the worker, investigate the problems, and develop a
corrective plan
c. File a secret memo in the worker's personnel file so as to not
embarrass them
d. Be extra nice to the employee on the theory that honey catches more
flies than vinegar. Answer: b. Meet with the worker, investigate the
problems, and develop a corrective plan
⩥ The products of the KIR gene system are...
a. Non-Polymorphic
b. Homologous to the HLA antigens
c. Detect self through HLA class I
d. Detect HLA-DRB4 null alleles. Answer: c. Detect self through HLA
class I
⩥ In a typical HLA laboratory, what would be the order of total annual
costs from greatest to least?
a. Amortized equipment>supplies>reagents
b. Reagents>supplies>salaries
, c. Salaries>reagents>amortized equipment
d. Reagents>amortized equipment>salaries. Answer: c.
Salaries>reagents>amortized equipment
⩥ The absolute A260 and A280 values and their ratio for a DNA sample
provide what information?
a. Length and concentration
b. Free 3' ends and length
c. Concentration and RNA/Protein contamination
d. Concentration and percent degraded. Answer: c. Concentration and
RNA/Protein contamination
⩥ Which statement is true regarding the relative number in normal
blood?
a. Lymphocytes>RBC
b. Granulocytes>lymphocytes c. RBC>platelets
d. Lymphocytes>WBC. Answer: b. Granulocytes>lymphocytes
⩥ KIR gene products are normally expressed upon...
a. NK cells
SPECIALIST ACTUAL EXAM 2026 200
COMPLETE QUESTIONS AND ANSWERS
ADVANCED PREPARATION KIT TRUSTED
RESOURCE GRADED A+
⩥ What approach is even better than the correct answer to :Reagent X
arrives in the lab without an expiration date. What action should you
take?=Obtain manufacturer and HLA lab recommendations and derive
an expiration date.
a. Read over the ASHI manual and find published expiration guidelines
b. Buy two bottles of the chemical. Store one, as recommended, at 4C
and the other at RT. When the RT one goes bad you know the 4C is also
bad
c. Periodically QC the reagent and develop a QA analysis of its
performance
d. Employ Google on a monthly schedule to look for reports of adverse
outcomes using older lots of the reagent. Answer: c. Periodically QC the
reagent and develop a QA analysis of its performance
⩥ A supervisor notices that a previously meticulous worker has been
making an inordinate number of mistakes in clinical assays. What
approach should the supervisor take?
,a. Use the power of peer pressure by emailing defamatory reports on the
employee to co-workers
b. Meet with the worker, investigate the problems, and develop a
corrective plan
c. File a secret memo in the worker's personnel file so as to not
embarrass them
d. Be extra nice to the employee on the theory that honey catches more
flies than vinegar. Answer: b. Meet with the worker, investigate the
problems, and develop a corrective plan
⩥ The products of the KIR gene system are...
a. Non-Polymorphic
b. Homologous to the HLA antigens
c. Detect self through HLA class I
d. Detect HLA-DRB4 null alleles. Answer: c. Detect self through HLA
class I
⩥ In a typical HLA laboratory, what would be the order of total annual
costs from greatest to least?
a. Amortized equipment>supplies>reagents
b. Reagents>supplies>salaries
, c. Salaries>reagents>amortized equipment
d. Reagents>amortized equipment>salaries. Answer: c.
Salaries>reagents>amortized equipment
⩥ The absolute A260 and A280 values and their ratio for a DNA sample
provide what information?
a. Length and concentration
b. Free 3' ends and length
c. Concentration and RNA/Protein contamination
d. Concentration and percent degraded. Answer: c. Concentration and
RNA/Protein contamination
⩥ Which statement is true regarding the relative number in normal
blood?
a. Lymphocytes>RBC
b. Granulocytes>lymphocytes c. RBC>platelets
d. Lymphocytes>WBC. Answer: b. Granulocytes>lymphocytes
⩥ KIR gene products are normally expressed upon...
a. NK cells
