CHS CERTIFIED HISTOCOMPATIBILITY
SPECIALIST EXAM SCRIPT 2026 200
SOLVED QUESTIONS DETAILED ANSWER
GUIDE PREMIUM PREP CONTENT GRADED
A+
⩥ ____ a EDTA is preferred over ACD as an additive for molecular
testing. Answer: True
⩥ ____ b- EDTA chelates calcium and is acceptable for CDC assays.
Answer: False
⩥ ____ c- EDTA is acceptable for flow cytometry assays. Answer: True
⩥ ____ d- Moderate hemolysis of serum should not interfere with PRA
testing. Answer: True
⩥ ____ e- Plasma is unacceptable for CDC PRA testing. Answer: True
⩥ ____ f- Heparinized blood is acceptable for molecular testing.
Answer: True, MOSTLY
,⩥ ____ g- Heparin does not interfere with Taq polymerase. Answer:
False
⩥ ____ h- Lithium heparin is an acceptable substitute for sodium
heparin. Answer: False
⩥ ____ i- It is acceptable for a red top to be collected from a patient who
is at that moment receiving a dialysis treatment. Answer: False
⩥ ____ j- Blood shipped to the lab for serology testing should be kept at
4 degrees. Answer: False
⩥ ____ k- Patients receiving long-term steroid treatment may have
insufficient lymphocytes for HLA testing. Answer: True
⩥ ____ l- Patients receiving blood products should have their blood
collected for HLA typing immediately following the transfusions to
ensure adequate cell numbers. Answer: False
⩥ ____ m- You should ask for the WBC and differential on leukopenic
and pediatric patients to determine how much blood should be collected
for HLA typing. Answer: True
⩥ ____ n- Requisition forms must include name of an authorized
requester. Answer: True
,⩥ ____ o- Plain red top, EDTA and ACD are all acceptable samples for
ABO blood grouping. Answer: True
⩥ ____ p- Lymphocytes from EBV transformed cell lines react the same
as PBLs in CDC assays. Answer: False
⩥ ____ q- The color of the stopper is a universal code for a vacutainer's
contents. Answer: False
⩥ ____ r- EDTA blood stored for 1 year at RT is an acceptable sample.
Answer: False
⩥ ____ s- Blood spotted on SS 903 cards and stored for 1 year at RT is
an acceptable sample. Answer: True
⩥ ____ t- ACD tubes maintain cell viability are better than heparin
during long transit times. Answer: True
⩥ When planning to start up a new lab, in what order should you do the
following?
1. Secure adequate work space
2. Hire all personnel
, 3. Obtain accreditation
4. Determine necessary services
b. 1,2,3,4
c. 2,3,1,4
d. 4,1,2,3
e. 4,3,2,1
f. none of the above. Answer: c. 2,3,1,4
⩥ Maslow's hierarchy of needs indicates for individuals whose basic
needs for food and shelter are met, the next need is
a. Esteem
b. Social
c. Self-actualization
d. Safety
e. None of the above. Answer: d. Safety
⩥ Which of the following is not part of a quality assurance program?
a. Checking freezer temperature daily
b. Annual competency evaluation
SPECIALIST EXAM SCRIPT 2026 200
SOLVED QUESTIONS DETAILED ANSWER
GUIDE PREMIUM PREP CONTENT GRADED
A+
⩥ ____ a EDTA is preferred over ACD as an additive for molecular
testing. Answer: True
⩥ ____ b- EDTA chelates calcium and is acceptable for CDC assays.
Answer: False
⩥ ____ c- EDTA is acceptable for flow cytometry assays. Answer: True
⩥ ____ d- Moderate hemolysis of serum should not interfere with PRA
testing. Answer: True
⩥ ____ e- Plasma is unacceptable for CDC PRA testing. Answer: True
⩥ ____ f- Heparinized blood is acceptable for molecular testing.
Answer: True, MOSTLY
,⩥ ____ g- Heparin does not interfere with Taq polymerase. Answer:
False
⩥ ____ h- Lithium heparin is an acceptable substitute for sodium
heparin. Answer: False
⩥ ____ i- It is acceptable for a red top to be collected from a patient who
is at that moment receiving a dialysis treatment. Answer: False
⩥ ____ j- Blood shipped to the lab for serology testing should be kept at
4 degrees. Answer: False
⩥ ____ k- Patients receiving long-term steroid treatment may have
insufficient lymphocytes for HLA testing. Answer: True
⩥ ____ l- Patients receiving blood products should have their blood
collected for HLA typing immediately following the transfusions to
ensure adequate cell numbers. Answer: False
⩥ ____ m- You should ask for the WBC and differential on leukopenic
and pediatric patients to determine how much blood should be collected
for HLA typing. Answer: True
⩥ ____ n- Requisition forms must include name of an authorized
requester. Answer: True
,⩥ ____ o- Plain red top, EDTA and ACD are all acceptable samples for
ABO blood grouping. Answer: True
⩥ ____ p- Lymphocytes from EBV transformed cell lines react the same
as PBLs in CDC assays. Answer: False
⩥ ____ q- The color of the stopper is a universal code for a vacutainer's
contents. Answer: False
⩥ ____ r- EDTA blood stored for 1 year at RT is an acceptable sample.
Answer: False
⩥ ____ s- Blood spotted on SS 903 cards and stored for 1 year at RT is
an acceptable sample. Answer: True
⩥ ____ t- ACD tubes maintain cell viability are better than heparin
during long transit times. Answer: True
⩥ When planning to start up a new lab, in what order should you do the
following?
1. Secure adequate work space
2. Hire all personnel
, 3. Obtain accreditation
4. Determine necessary services
b. 1,2,3,4
c. 2,3,1,4
d. 4,1,2,3
e. 4,3,2,1
f. none of the above. Answer: c. 2,3,1,4
⩥ Maslow's hierarchy of needs indicates for individuals whose basic
needs for food and shelter are met, the next need is
a. Esteem
b. Social
c. Self-actualization
d. Safety
e. None of the above. Answer: d. Safety
⩥ Which of the following is not part of a quality assurance program?
a. Checking freezer temperature daily
b. Annual competency evaluation
