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CPNRE Exam Prep – Practice Questions and Expertly Verified Answers (2025/2026)

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This document contains practice questions and expertly verified answers for CPNRE exam preparation for the 2025/2026 period. It covers important nursing concepts, patient care scenarios, clinical judgment, pharmacology, and professional practice topics commonly assessed on the Canadian Practical Nurse Registration Examination. The material is designed to support revision and strengthen understanding of key nursing competencies through structured practice questions and answer explanations. It is useful for self-study, exam preparation, and reinforcing practical nursing knowledge.

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CPNRE
Vak
CPNRE

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CPNRE EXAM PREP / QUESTIONS
& EXPERTLY VERIFIED ANSWERS
GRADED A+, 2026.
What is the most effective method to assess respiratory distress syndrome in an infant?
- answer-Assess if the child has any sign of nasal flaring



What is an acceptable serum potassium level? - answer-4 to 5 is acceptable. If 6 or
above, inform the physician immediately



What is the most effective intervention if respiratory syncytial virus is suspected? -
answer-Assess the patient's respirations and respiratory pattern



What is, and when is the phenylketonuria metabolism test done? - answer-The
phenylketonuria metabolism test is designed to assess whether or not newborn infant
has the enzyme needed to used phenylalanine. The test is done between 24-48 hours
after birth. It is measured by pricking the heel of the newborn infant and drawing blood



What is the most effective method to administrator eye drop medication? - answer-To
the middle of the conjunctival sac of the eye



What happens if the mother is Rh +and the infant is Rh-? - answer-An Rh +mother
carrying an Rh-fetus will not have a problem. The reasons for this is that the Rh factor is
an antigen on the outside of the erythrocytes, just like the A and B antigens. Because it
is an antigen, antibodies can be formed to it. In Rh incompatibility, an Rh- mother who is
carrying an Rh+ fetus will have no issue during the first pregnancy, because fetal blood
cells do not enter the mothers system to cause an immune response. However, during
childbirth, some blood always escapes the placenta, and if it is left in the mothers body,
her immune system will respond accordingly, creating antibodies and memory cells.in
subsequent pregnancies, her antibodies enter the fetus' body and begin the destroy the
fetal erythrocytes. An Rh-fetus has no Rh antigens to induce antibody creation in either
an Rh- or R+ mother. The fetal immune system not yet developed enough to create
antibodies to the mothers Rh+ antigens

,What happens if the mother is Rh- and the infant is Rh+? - answer-If the mother is Rh-
and the baby is Rh+, the mother produces antibodies (including lgG) against the Rhesus
D antigen within the fetus' erythrocytes. During this and subsequent pregnancies,IgG is
able to pass through the placenta an into the fetus, and if the level is high enough, it will
cause destruction and deterioration of Rhesus D positive fetal erythrocytes leading to
the development of Rh disease.



Do Rh - and Rh+ incompatibility issues get worse with subsequent pregnancies? -
answer-Yes. Generally, Rhesus disease becomes worse with each additional Rhesus
incompatible pregnancy



What is the most common eating disorder? - answer-Anorexia



How are seizures assessed and recorded? - answer-aura, incontinence, and awareness



What is the most common side effect of antibiotics? - answer-Diarrhea



What are the most common side effects of antipsychotics? - answer-Hives and chills



How is insulin prepared? - answer-Short acting first (Humalin R), long acting second
(Humalin N)



How is pathological jaundice treated in an infant? - answer-Phototherapy is used
because is speeds up bilirubin breakdown time . Genitals and eyes must be covered
during phototherapy. Reposition infant Q2H. Any infant with a total serum bilirubin
greater than 21 mg/dL should receive phototherapy



What is the difference between infiltration and interstitial? - answer-Nothing. They are
the exact same IV complication causing the surrounding IV site tissue to be cold

,What is the difference between phlebitis and vein inflammation? - answer-Nothing.
They are the exact same IV complication causing the surrounding IV site tissue to be
warm



What is the most common symptom after a craniotomy? - answer-Slurred speech



What is the BUBBLE assessment and when is it used? - answer-Bubble is used to
assess mothers post partum and stands for....B (Breasts)U (Uterus)B (Bladder)B
(Bowel)L (Lochia)E (Episiotomy)



What is a common side effect of iron supplementation? - answer-Black stool



What is the best method to perform a procedure on a child? - answer-Use a teddy bear
and show the child what you are doing. (T for toddler, for teddy bear)



What is a common side effect with steroid (Prednisone) treatment? - answer-Increased
blood glucose levels. Increase insulin dosage



When should digoxin be held? - answer-If the apical pulse is below 60 in adults and
below 90 in children



What are the 3 most common methods an NG tube placement is verified? - answer-X-
Ray is most accurate. Aspiration is less accurate but most commonly used.
Auscultation is least accurate and seldom used



How are NG tubes medications administered? - answer-Flush the tubing with 30 - 60 ml
of warm water to ensure patency and reduce any cramping of the GI tract. Crush any PO
medications, mix with liquid medications, and administer, flush the tubing again after
the medication administration with 30 - 60 ml of warm water, place patient in High
fowlers position for 30 minutes afterwards to prevent aspiration

, What is the best method to assist a patient with CVA weakness (left or right side)? -
answer-Always assist on weaker side and place the chair the patient will soon sit in, on
stronger side. Place food on the stronger side of the mouth.



What side is affected with a left sided CVA? - answer-The right side is affected, making
the left side the stronger side



What side is affected with the right side CVA? - answer-The left side is affected, making
the right side the stronger side



If the patients MAR directs to give Digoxin and an antacid, which is administered first? -
answer-Give Digoxin first, and then antacid 2 - 3 hours later as these 2 medications
interact negatively



If the patients MAR directs to give Digoxin and antibiotic, which is administered first? -
answer-Give Digoxin first, and then antibiotic 2 - 3 hours later as these 2 medications
interact negatively



If the patients MAR directs to give Digoxin and Naproxen, which is administered first? -
answer-Give Naproxen first Pain medications are always top priority



What are common side effects of Demerol? - answer-Headache, fatigue, nausea,
lethargy, constipation, blurred vision, and drowsiness



What is the most common side effect of Demerol? - answer-Respiratory depression



What are the most common PO dosages of Demerol? - answer-50 and 100 mg



What are the Most common PO dosages of Digoxin? - answer-0.125 - 0.25 mg

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