COMSAE Phase 3 Assessment Form B
Questions With Correct Answers
(Verified Answers) Plus Rationales
2026 Q&A | Instant Download Pdf
Question 1
A 62-year-old man presents with crushing substernal chest pain radiating
to the left arm. ECG shows ST-segment elevation in leads II, III, and
aVF. Which coronary artery is most likely occluded?
A. Left anterior descending artery
B. Right coronary artery
C. Left circumflex artery
D. Left main coronary artery
Answer: B
Rationale: Inferior wall myocardial infarction (leads II, III, aVF) is
most commonly caused by occlusion of the right coronary artery,
which supplies the inferior portion of the left ventricle in most
individuals.
,Question 2
A patient with chronic hypertension develops exertional dyspnea.
Echocardiography shows concentric left ventricular hypertrophy with
preserved ejection fraction. What is the most likely diagnosis?
A. Dilated cardiomyopathy
B. Heart failure with reduced ejection fraction
C. Heart failure with preserved ejection fraction
D. Restrictive cardiomyopathy
Answer: C
Rationale: Long-standing hypertension leads to diastolic dysfunction
due to concentric hypertrophy, resulting in HFpEF with preserved
systolic function.
Question 3
Which medication is most appropriate for acute anaphylaxis
management?
A. Diphenhydramine
B. Epinephrine
C. Albuterol
D. Prednisone
Answer: B
,Rationale: Epinephrine is the first-line treatment for anaphylaxis due
to its alpha and beta adrenergic effects that reverse bronchospasm and
hypotension.
Question 4
A 45-year-old man has chronic cough and foul-smelling sputum.
Imaging shows bronchial dilation. What is the diagnosis?
A. Chronic bronchitis
B. Bronchiectasis
C. Emphysema
D. Asthma
Answer: B
Rationale: Bronchiectasis involves irreversible bronchial dilation often
due to recurrent infections, leading to productive cough with purulent
sputum.
Question 5
A patient presents with tremor, weight loss, and heat intolerance. Lab
shows low TSH and elevated T3/T4. What is the most likely diagnosis?
A. Hashimoto thyroiditis
B. Graves disease
, C. Thyroid cancer
D. Subacute thyroiditis
Answer: B
Rationale: Graves disease is an autoimmune hyperthyroidism
characterized by low TSH and elevated thyroid hormones.
Question 6
Which structure is primarily responsible for reabsorption of glucose in
the kidney?
A. Collecting duct
B. Distal convoluted tubule
C. Proximal convoluted tubule
D. Loop of Henle
Answer: C
Rationale: The proximal convoluted tubule reabsorbs nearly all
filtered glucose via sodium-glucose cotransporters.
Question 7
A child presents with edema and frothy urine. Urinalysis shows heavy
proteinuria. What is the most likely diagnosis?
A. Nephritic syndrome
Questions With Correct Answers
(Verified Answers) Plus Rationales
2026 Q&A | Instant Download Pdf
Question 1
A 62-year-old man presents with crushing substernal chest pain radiating
to the left arm. ECG shows ST-segment elevation in leads II, III, and
aVF. Which coronary artery is most likely occluded?
A. Left anterior descending artery
B. Right coronary artery
C. Left circumflex artery
D. Left main coronary artery
Answer: B
Rationale: Inferior wall myocardial infarction (leads II, III, aVF) is
most commonly caused by occlusion of the right coronary artery,
which supplies the inferior portion of the left ventricle in most
individuals.
,Question 2
A patient with chronic hypertension develops exertional dyspnea.
Echocardiography shows concentric left ventricular hypertrophy with
preserved ejection fraction. What is the most likely diagnosis?
A. Dilated cardiomyopathy
B. Heart failure with reduced ejection fraction
C. Heart failure with preserved ejection fraction
D. Restrictive cardiomyopathy
Answer: C
Rationale: Long-standing hypertension leads to diastolic dysfunction
due to concentric hypertrophy, resulting in HFpEF with preserved
systolic function.
Question 3
Which medication is most appropriate for acute anaphylaxis
management?
A. Diphenhydramine
B. Epinephrine
C. Albuterol
D. Prednisone
Answer: B
,Rationale: Epinephrine is the first-line treatment for anaphylaxis due
to its alpha and beta adrenergic effects that reverse bronchospasm and
hypotension.
Question 4
A 45-year-old man has chronic cough and foul-smelling sputum.
Imaging shows bronchial dilation. What is the diagnosis?
A. Chronic bronchitis
B. Bronchiectasis
C. Emphysema
D. Asthma
Answer: B
Rationale: Bronchiectasis involves irreversible bronchial dilation often
due to recurrent infections, leading to productive cough with purulent
sputum.
Question 5
A patient presents with tremor, weight loss, and heat intolerance. Lab
shows low TSH and elevated T3/T4. What is the most likely diagnosis?
A. Hashimoto thyroiditis
B. Graves disease
, C. Thyroid cancer
D. Subacute thyroiditis
Answer: B
Rationale: Graves disease is an autoimmune hyperthyroidism
characterized by low TSH and elevated thyroid hormones.
Question 6
Which structure is primarily responsible for reabsorption of glucose in
the kidney?
A. Collecting duct
B. Distal convoluted tubule
C. Proximal convoluted tubule
D. Loop of Henle
Answer: C
Rationale: The proximal convoluted tubule reabsorbs nearly all
filtered glucose via sodium-glucose cotransporters.
Question 7
A child presents with edema and frothy urine. Urinalysis shows heavy
proteinuria. What is the most likely diagnosis?
A. Nephritic syndrome
