Page 1 of 30
HESI PHARM 315 – 2026 QUESTIONS MOST
COMPREHENSIVE 2026 QUESTIONS EXAM LATEST
VERSION SOLVED QUESTIONS & ANSWERS VERIFIED
100 %
A client taking atorvastatin develops an increased serum creatine
phosphokinase (CK) level. The nurse should assess the client for the onset of
which problem?
A. Muscle tenderness.
B. Nausea and vomiting.
C. Excessive bruising.
D. Peripheral edema.
A. Muscle tenderness.
An increase in which serum laboratory value indicates to the nurse that a
prescription for atorvastatin is having the desired effect for a client at risk for
coronary artery disease?
A. LDL (Low-density lipoprotein)
B. Triglycerides (Type of fat)
C. HDL (High-density lipoprotein)
D. VLDL (Very low-density lipoprotein)
C. HDL (High-density lipoprotein)
NGN - Patient Data
History and Physical:
The client is a 36-year-old female with moderate persistent asthma. She takes
fluticasone/salmeterol 250 mcg/50 mcg 1 inhalation twice daily and albuterol
90 mcg/inhalation 2 inhalations every 4-6 hours as needed.
Nurses notes:
, Page 2 of 30
The client states that she has had more severe asthma symptoms than usual
in the past week. Her forced expiratory volume has been 60-65% even with
multiple doses of albuterol for several days in a row. She came to the hospital
feeling dizzy, lightheaded, and complaining of “heart palpitations”. Upon
assessment, no wheezes were found. Her oxygen saturation is 99%.
Review H and P, and nurse’s note. Identify from the choices below which
condition the client is most likely experiencing, two actions the nurse should
take to address that condition, and two parameters the nurse should monitor
to assess the client’s progress.
Potential Condition:
Methemoglobinemia
Actions to Take:
1. Draw blood for a complete blood count
2. Administer methylene blue
Parameters to Monitor:
1. Methemoglobin level
2. Heart rate and rhythm
The nurse provide discharge instructions to a client who has been
prescribed gabapentin 300 mg by mouth three times a day for post herpetic
neuralgia. Which symptoms should the nurse tell the client to report to the
healthcare provider?
A. Sexual dysfunction
B. Gastric irritation
C. Rapid weight gain
D. Photosensitivity
B. Gastric irritation
A client with chronic lower back pain has been taking non steroidal anti-
inflammatory (NSAID) drug ibuprofen by mouth twice a day for several
months. Which assessment is most important for the nurse to complete?
A. Assess back pain using numeric scale
B. Palpate volume of pedal pulses
C. Determine presence of abdominal pain
D. Evaluate ongoing sleep patterns
C. Determine presence of abdominal pain
, Page 3 of 30
The nurse administers risedrineate to a client with osteoporosis at 0700. The
client asks for a glass of milk to drink with the medication. Which action
should the nurse take?
A. Instruct the client that it is necessary to take nothing but water with the
medication.
B. Assign an unlicensed assistive personnel (UAP) to bring the client a glass
of low fat milk.
C. Withhold the medication until the client's breakfast tray is available on the
unit.
D. Consult with a pharmacist about scheduling the dose one hour after the
client eats.
A. Instruct the client that it is necessary to take nothing but water with the
medication.
Which action should the nurse implement to assess the effectiveness
of calcium channel blocker amlodipine?
A. Note the clients serum calcium levels
B. Monitor the clients serum electrolytes
C. Review the clients intake and output
D. Measure the clients blood pressure
D. Measure the clients blood pressure
A client is receiving tamsulosin an alpha adrenergic - blocking agent for the
management of urinary retention due to benign prostatic hyperplasia (BPH).
Which instruction is most important for the nurse to provide?
A. Use a twice a week dosing schedule
B. Stand and sit up slowly
C. Take the medication early in the day
D. Reduce daily fluid intake
B. Stand and sit up slowly
A client with chemotherapy induced nausea receives a prescription
for metoclopramide. Which adverse effect is most important for the nurse to
report?
A. Nausea
B. Involuntary movements
C. Diarrhea
HESI PHARM 315 – 2026 QUESTIONS MOST
COMPREHENSIVE 2026 QUESTIONS EXAM LATEST
VERSION SOLVED QUESTIONS & ANSWERS VERIFIED
100 %
A client taking atorvastatin develops an increased serum creatine
phosphokinase (CK) level. The nurse should assess the client for the onset of
which problem?
A. Muscle tenderness.
B. Nausea and vomiting.
C. Excessive bruising.
D. Peripheral edema.
A. Muscle tenderness.
An increase in which serum laboratory value indicates to the nurse that a
prescription for atorvastatin is having the desired effect for a client at risk for
coronary artery disease?
A. LDL (Low-density lipoprotein)
B. Triglycerides (Type of fat)
C. HDL (High-density lipoprotein)
D. VLDL (Very low-density lipoprotein)
C. HDL (High-density lipoprotein)
NGN - Patient Data
History and Physical:
The client is a 36-year-old female with moderate persistent asthma. She takes
fluticasone/salmeterol 250 mcg/50 mcg 1 inhalation twice daily and albuterol
90 mcg/inhalation 2 inhalations every 4-6 hours as needed.
Nurses notes:
, Page 2 of 30
The client states that she has had more severe asthma symptoms than usual
in the past week. Her forced expiratory volume has been 60-65% even with
multiple doses of albuterol for several days in a row. She came to the hospital
feeling dizzy, lightheaded, and complaining of “heart palpitations”. Upon
assessment, no wheezes were found. Her oxygen saturation is 99%.
Review H and P, and nurse’s note. Identify from the choices below which
condition the client is most likely experiencing, two actions the nurse should
take to address that condition, and two parameters the nurse should monitor
to assess the client’s progress.
Potential Condition:
Methemoglobinemia
Actions to Take:
1. Draw blood for a complete blood count
2. Administer methylene blue
Parameters to Monitor:
1. Methemoglobin level
2. Heart rate and rhythm
The nurse provide discharge instructions to a client who has been
prescribed gabapentin 300 mg by mouth three times a day for post herpetic
neuralgia. Which symptoms should the nurse tell the client to report to the
healthcare provider?
A. Sexual dysfunction
B. Gastric irritation
C. Rapid weight gain
D. Photosensitivity
B. Gastric irritation
A client with chronic lower back pain has been taking non steroidal anti-
inflammatory (NSAID) drug ibuprofen by mouth twice a day for several
months. Which assessment is most important for the nurse to complete?
A. Assess back pain using numeric scale
B. Palpate volume of pedal pulses
C. Determine presence of abdominal pain
D. Evaluate ongoing sleep patterns
C. Determine presence of abdominal pain
, Page 3 of 30
The nurse administers risedrineate to a client with osteoporosis at 0700. The
client asks for a glass of milk to drink with the medication. Which action
should the nurse take?
A. Instruct the client that it is necessary to take nothing but water with the
medication.
B. Assign an unlicensed assistive personnel (UAP) to bring the client a glass
of low fat milk.
C. Withhold the medication until the client's breakfast tray is available on the
unit.
D. Consult with a pharmacist about scheduling the dose one hour after the
client eats.
A. Instruct the client that it is necessary to take nothing but water with the
medication.
Which action should the nurse implement to assess the effectiveness
of calcium channel blocker amlodipine?
A. Note the clients serum calcium levels
B. Monitor the clients serum electrolytes
C. Review the clients intake and output
D. Measure the clients blood pressure
D. Measure the clients blood pressure
A client is receiving tamsulosin an alpha adrenergic - blocking agent for the
management of urinary retention due to benign prostatic hyperplasia (BPH).
Which instruction is most important for the nurse to provide?
A. Use a twice a week dosing schedule
B. Stand and sit up slowly
C. Take the medication early in the day
D. Reduce daily fluid intake
B. Stand and sit up slowly
A client with chemotherapy induced nausea receives a prescription
for metoclopramide. Which adverse effect is most important for the nurse to
report?
A. Nausea
B. Involuntary movements
C. Diarrhea
