COMSAE High-Yield Systems Review Exam
Questions With Correct Answers (Verified
Answers) Plus Rationales 2026 Q&A | Instant
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1. A 68-year-old man presents with exertional chest pain relieved by
rest. ECG shows ST depression during pain episodes. Which is the
most likely diagnosis?
A. Variant (Prinzmetal) angina
B. Stable angina
C. STEMI
D. Pericarditis
Correct answer: B
Rationale: Stable angina is characterized by predictable chest
pain with exertion that is relieved by rest or nitroglycerin. ST
depression suggests subendocardial ischemia rather than
transmural infarction.
,2. A patient has acute chest pain that improves when leaning
forward. ECG shows diffuse ST elevation and PR depression.
Diagnosis?
A. Myocardial infarction
B. Pericarditis
C. Aortic dissection
D. GERD
Correct answer: B
Rationale: Pericarditis classically presents with positional chest
pain and diffuse ST elevation with PR depression due to
inflammation of the pericardium.
3. A 25-year-old with asthma develops wheezing after beta-blocker
use. Mechanism?
A. β1 stimulation
B. β2 blockade
C. Muscarinic activation
D. Histamine release
Correct answer: B
Rationale: Nonselective beta-blockers inhibit β2 receptors in
bronchial smooth muscle, leading to bronchoconstriction.
,4. Which organism is most associated with “currant jelly” sputum
pneumonia?
A. Streptococcus pneumoniae
B. Klebsiella pneumoniae
C. Mycoplasma pneumoniae
D. Legionella pneumophila
Correct answer: B
Rationale: Klebsiella pneumoniae causes necrotizing pneumonia
with thick mucoid “currant jelly” sputum, especially in alcoholics.
5. A child presents with a barking cough and inspiratory stridor. Most
likely diagnosis?
A. Epiglottitis
B. Bronchiolitis
C. Croup
D. Asthma
Correct answer: C
Rationale: Croup (parainfluenza virus) causes subglottic edema
leading to barking cough and inspiratory stridor.
, 6. Which vitamin deficiency causes night blindness?
A. Vitamin B12
B. Vitamin A
C. Vitamin D
D. Vitamin K
Correct answer: B
Rationale: Vitamin A is essential for rhodopsin formation in the
retina; deficiency leads to night blindness.
7. A patient with chronic alcohol use presents with confusion,
ophthalmoplegia, and ataxia. Treatment?
A. Thiamine
B. Niacin
C. Folic acid
D. Pyridoxine
Correct answer: A
Rationale: Wernicke encephalopathy is treated with thiamine to
prevent progression to Korsakoff syndrome.
8. Which acid-base disorder is seen in uncontrolled diabetes
mellitus?
Questions With Correct Answers (Verified
Answers) Plus Rationales 2026 Q&A | Instant
Download Pdf
1. A 68-year-old man presents with exertional chest pain relieved by
rest. ECG shows ST depression during pain episodes. Which is the
most likely diagnosis?
A. Variant (Prinzmetal) angina
B. Stable angina
C. STEMI
D. Pericarditis
Correct answer: B
Rationale: Stable angina is characterized by predictable chest
pain with exertion that is relieved by rest or nitroglycerin. ST
depression suggests subendocardial ischemia rather than
transmural infarction.
,2. A patient has acute chest pain that improves when leaning
forward. ECG shows diffuse ST elevation and PR depression.
Diagnosis?
A. Myocardial infarction
B. Pericarditis
C. Aortic dissection
D. GERD
Correct answer: B
Rationale: Pericarditis classically presents with positional chest
pain and diffuse ST elevation with PR depression due to
inflammation of the pericardium.
3. A 25-year-old with asthma develops wheezing after beta-blocker
use. Mechanism?
A. β1 stimulation
B. β2 blockade
C. Muscarinic activation
D. Histamine release
Correct answer: B
Rationale: Nonselective beta-blockers inhibit β2 receptors in
bronchial smooth muscle, leading to bronchoconstriction.
,4. Which organism is most associated with “currant jelly” sputum
pneumonia?
A. Streptococcus pneumoniae
B. Klebsiella pneumoniae
C. Mycoplasma pneumoniae
D. Legionella pneumophila
Correct answer: B
Rationale: Klebsiella pneumoniae causes necrotizing pneumonia
with thick mucoid “currant jelly” sputum, especially in alcoholics.
5. A child presents with a barking cough and inspiratory stridor. Most
likely diagnosis?
A. Epiglottitis
B. Bronchiolitis
C. Croup
D. Asthma
Correct answer: C
Rationale: Croup (parainfluenza virus) causes subglottic edema
leading to barking cough and inspiratory stridor.
, 6. Which vitamin deficiency causes night blindness?
A. Vitamin B12
B. Vitamin A
C. Vitamin D
D. Vitamin K
Correct answer: B
Rationale: Vitamin A is essential for rhodopsin formation in the
retina; deficiency leads to night blindness.
7. A patient with chronic alcohol use presents with confusion,
ophthalmoplegia, and ataxia. Treatment?
A. Thiamine
B. Niacin
C. Folic acid
D. Pyridoxine
Correct answer: A
Rationale: Wernicke encephalopathy is treated with thiamine to
prevent progression to Korsakoff syndrome.
8. Which acid-base disorder is seen in uncontrolled diabetes
mellitus?
