3/25/26, 3:51 PM
NURS 6521 PHARMACOLOGY AND DRUG THERAPY KEY
CONCEPTS FOR MIDTERM
What is the impact of agonists, antagonists, and partial They affect drug levels and dosing through mechanisms of action and interactions.
agonists on drug levels and dosing?
What is bioavailability? The proportion of a drug that enters circulation when introduced into the body.
What is the first pass effect? The metabolism of a drug before it reaches systemic circulation.
What does EC50 represent? The concentration of a drug that produces 50% of its maximal effect.
What is maximal efficacy? The greatest effect that a drug can produce.
What are G protein-coupled receptors? A large family of receptors that detect molecules outside the cell and activate internal
signal transduction pathways.
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NURS 6521 PHARMACOLOGY AND DRUG THERAPY KEY
CONCEPTS FOR MIDTERM
What is the impact of agonists, antagonists, and partial They affect drug levels and dosing through mechanisms of action and interactions.
agonists on drug levels and dosing?
What is bioavailability? The proportion of a drug that enters circulation when introduced into the body.
What is the first pass effect? The metabolism of a drug before it reaches systemic circulation.
What does EC50 represent? The concentration of a drug that produces 50% of its maximal effect.
What is maximal efficacy? The greatest effect that a drug can produce.
What are G protein-coupled receptors? A large family of receptors that detect molecules outside the cell and activate internal
signal transduction pathways.
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