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2026
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Terms in this set (93)
Anticoagulant, Antiplatelet, and P2Y12 adenosine diphosphate (ADP) receptor
Thrombolytic Drugs: blockers
Question 1 of 5 Clopidogrel is an example of a P2Y12 ADP receptor
Clopidogrel is an example of which blocker.
class of antiplatelets?
Cyclooxygenase inhibitors
Anticoagulants
P2Y12 adenosine diphosphate (ADP)
receptor blockers
Glycoprotein IIb/IIIa receptor
blockers
Question 2 of 5 Liver
In which organ is clopidogrel Clopidogrel is activated in the liver primarily by the
activated for its drug effects? hepatic CYP2C19 enzyme system.
Kidney
Stomach
Liver
Small intestines
,Question 3 of 5 Decrease platelet aggregation
Which phrases describe the main Antiplatelets are drugs that decrease platelet
functions of antiplatelet drugs? aggregation. This prevents platelets from sticking
Select all that apply. together to form a blood clot.
Suppress the production of clotting
factors Inhibit thrombus formation
Decrease platelet aggregation Antiplatelets are drugs that inhibit thrombus (blood
Prevent the conversion of fibrinogen clot) formation. When platelets cannot stick
to fibrin together, a thrombus cannot form.
Inhibit thrombus formation
Prevent antithrombin from
converting to thrombin
Question 4 of 5 Transient ischemic attacks (TIAs)
Prophylactic therapy with Patients with TIAs are at an increased risk for
antiplatelet drugs is indicated in thromboembolic stroke. Antiplatelet drugs are
patients with a history of which indicated for these patients to prevent future TIAs
conditions? or ischemic stroke from a thromboembolus
Select all that apply. .
Peptic ulcers History of myocardial infarction (MI)
Transient ischemic attacks (TIAs) Patients with a history of MIs are at an increased
History of myocardial infarction (MI) risk for future MIs due to thromboembolus.
Intracranial bleed Antiplatelet drugs are indicated for these patients.
Factor V Leiden deficiency
History of ischemic stroke Factor V Leiden deficiency
Factor V Leiden deficiency is a hypercoagulable
disorder which increases the risk for blood clots.
Antiplatelet drugs are indicated for patients with
factor V Leiden deficiency.
History of ischemic stroke
Patients with a history of ischemic strokes are at an
increased risk for a future ischemic stroke.
Antiplatelet drugs are indicated for these patients
to prevent future thromboembolism.
,Question 5 of 5 The onset of action for clopidogrel is 1-2 hours.
After administration, when would the
nurse expect clopidogrel to start
having its effect? __________ hours
Use numbers only.
, Side Effects and Adverse Effects of
Clopidogrel:
-Clopidogrel is generally a well-
tolerated drug and shares many of
the same side and adverse drug
effects as aspirin. Common side
effects include abdominal pain,
diarrhea, rash, and dyspepsia
(indigestion).
-TTP is a rare (3 to 4 in 1 million)
autoimmune blood disorder
characterized by clotting in small
blood vessels of the body, resulting
in low platelet count. Its clinical
manifestations include
thrombocytopenia, neurologic
symptoms, and fever.
General Teaching:
-Inform patients that some people
do not metabolize clopidogrel and
will not receive the same benefits.
Inform them that testing is available
to determine their status.
-Teach patients that clopidogrel
should be taken at the same time
each day, with or without food.
-Inform patients who are taking
clopidogrel to manage ACS that they
should also take aspirin (75 to 325
mg) daily.
-Instruct patients to inform a