NCLEX PRACTICE QUESTIONS
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This document, "NUR 2474 Pharmacology Exam 2 NCLEX Practice Questions," provides a comprehensive
review of pharmacology concepts for nursing students. It covers specific topics such as managing
cholesterol levels, heart failure, cardiac glycosides, laxatives, medication management, and asthma.
With 99 questions that include correct answers and detailed explanations, this document enables
students to study, review, and understand complex pharmacological concepts, ultimately aiding in their
preparation for the NCLEX exam.
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EXAM QUESTIONS
QUESTION 1
A nurse is caring for a client who has been prescribed a medication to manage cholesterol levels.
When providing patient education, which information should the nurse include?
A) The medication will replace a low-fat diet to manage cholesterol levels.
B) It is necessary to double the dose of the medication if one dose is missed.
C) Stopping the medication will alleviate constipation side effects.
D) Continuing an exercise program will help increase HDL serum levels.
CORRECT ANSWER
D) Continuing an exercise program will help increase HDL serum levels.
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, RATIONALE: Regular exercise can reduce LDL cholesterol and elevate HDL cholesterol. Encouraging the client to
continue their exercise program is crucial for managing cholesterol levels. The nurse should emphasize that exercise is
an adjunct to medication therapy, not a replacement. The client should not double the dose of medication if one is
missed, and stopping the medication will not alleviate constipation.
QUESTION 2
A client arrives at the emergency department with a history of angina, regularly using sublingual
nitroglycerin for symptom relief. The client expresses concern about increased frequency of episodes,
typically occurring after a regular morning walk. What action should the healthcare provider take?
A) Suggest a daily regimen of a higher dose of sublingual nitroglycerin.
B) Recommend a physical activity routine modification to shorter walks.
C) Order a prescription for a transdermal nitroglycerin patch for sustained relief.
D) Inquire about the client's daily consumption of foods high in nitrates.
CORRECT ANSWER
C) Order a prescription for a transdermal nitroglycerin patch for sustained relief.
RATIONALE: The client's increasing frequency of anginal episodes suggests a need for sustained prophylactic therapy.
Transdermal patches provide a steady release of nitroglycerin, offering more effective management of angina
symptoms. This approach aligns with guidelines for managing stable angina.
QUESTION 3
The nurse is assessing a patient who has a history of heart failure. The healthcare provider wants to
initiate first-line therapy. Which of the following medications is NOT part of the initial treatment
regimen?
A) Agents that inhibit the renin-angiotensin-aldosterone system (RAAS)
B) Beta blockers
C) Cardiac glycosides
D) Diuretics
CORRECT ANSWER
C) Cardiac glycosides
RATIONALE: Cardiac glycosides, such as digoxin, are not typically considered first-line therapy for heart failure. The
initial treatment regimen typically includes agents that inhibit the renin-angiotensin-aldosterone system (RAAS), beta
blockers, and diuretics to manage symptoms and reduce morbidity.
QUESTION 4
A patient has a prescription for a bulk-forming laxative to manage recurring constipation. Which of
the following patient statements best indicates understanding of the medication instructions?
A) "I can take this medication for the rest of my life."
B) "I need to take this with milk to help soften my stool."
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, C) "It's crucial to consume each dose with a full glass of water to enhance effectiveness."
D) "This medication is only necessary when I have diarrhea."
CORRECT ANSWER
C) "It's crucial to consume each dose with a full glass of water to enhance effectiveness."
RATIONALE: Taking each dose with a full glass of water is essential for bulk-forming laxatives to swell and soften the
stool. The other options are incorrect because this medication should not be taken long-term, consumption with milk is
not necessary, and it's used for constipation rather than diarrhea.
QUESTION 5
The nurse receives report on four clients requiring medication management. One client has a
prescription for magnesium hydroxide to relieve constipation. However, the client's lab results show a
history of chronic renal failure. Which condition would necessitate withholding the magnesium
hydroxide order?
A) Liver cirrhosis
B) Prostatic inflammation
C) Intestinal obstruction
D) Chronic renal failure
CORRECT ANSWER
D) Chronic renal failure
RATIONALE: The client's chronic renal failure increases the risk of magnesium accumulation to toxic levels. Withholding
the magnesium hydroxide order is necessary to prevent potential harm. The other conditions do not contraindicate the
medication, making them incorrect choices.
QUESTION 6
A client reports taking two medications for heart failure, and the nurse notes a potassium level of 5.5
mEq/L. Which drug combination should most concern the nurse regarding potential electrolyte
imbalances?
A) Spironolactone (Aldactone) and metoprolol (Lopressor)
B) Furosemide (Lasix) and enalapril (Vasotec)
C) Amlodipine (Norvasc) and eplerenone (Inspra)
D) Hydrochlorothiazide and enalapril
CORRECT ANSWER
C) Amlodipine (Norvasc) and eplerenone (Inspra)
RATIONALE: Eplerenone increases the risk of hyperkalemia, and combining it with a potassium-sparing diuretic like
spironolactone creates a significant risk of electrolyte imbalance. The other options do not have this combination,
making them less concerning.
QUESTION 7
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, A nurse observes that a client with atrial fibrillation is prescribed amiodarone (Cordarone). Which
baseline tests must be evaluated before starting this medication?
A) Liver function tests and renal function tests
B) Complete blood count with differential and thyroid function tests
C) Pulmonary function tests and complete blood count
D) Chest radiograph and renal function tests
CORRECT ANSWER
B) Complete blood count with differential and thyroid function tests
RATIONALE: To minimize the risk of amiodarone's toxic side effects, particularly thyroid toxicity, pulmonary toxicity, and
ophthalmic effects, it is essential to evaluate these systems at baseline. A complete blood count with differential and
thyroid function tests are necessary to monitor for these potential adverse effects.
QUESTION 8
After reviewing the client's chart, the nurse notes a laboratory value that warrants immediate
attention for a client taking digoxin and furosemide due to the risk of a serious cardiac complication.
A) Blood urea nitrogen (BUN) level of 30 mg/dL
B) Oxygen saturation of 88%
C) Serum potassium level of 3.0 mEq/L
D) Hemoglobin level of 12 g/dL
CORRECT ANSWER
C) Serum potassium level of 3.0 mEq/L
RATIONALE: The client's low serum potassium level places them at risk for a fatal dysrhythmia, especially when taking
digoxin. Furosemide contributes to potassium loss through its effects on the distal nephron. Monitoring potassium levels
closely is essential to prevent this complication.
QUESTION 9
The healthcare provider prescribes an antacid and ranitidine (Zantac) to a client with a history of
gastritis. Which instruction should the nurse give the client about taking the medications?
A) Take the antacid 15 minutes before the ranitidine.
B) Take the antacid at the same time as the ranitidine for better effect.
C) Take the antacid 30 minutes after the ranitidine.
D) Take the antacid 1 hour after the ranitidine.
CORRECT ANSWER
D) Take the antacid 1 hour after the ranitidine.
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