BIO 242 EXAM 3 QUESTIONS AND ANSWERS WITH COMPLETE
SOLUTIONS
Which lines of defense would be considered nonspecific and innate?
First line of defense
Second line of defense
Differentiate between components of first and second line defense
FIRST:Physical and Chemical barriers
SECOND: phagocytosis, inflammation, fever, antimicrobial proteins
FLOD: lysozome
is secreted in tears and saliva
What human body region is protected by fatty acids, acidic pH, lactic acid, and tough
cell barrier with its own normal biota?
skin
The sweat doud on skin and saliva in the mouth attributed to what line of defense?
First line
Eosinophils
attack parasitic helminths
Basophils
- make up less than .5% of circulating WBCs
- granules contain histamine
When monocytes migrate from the blood out to the tissues, they are transformed by
inflammatory mediators to develop into________
Macrophages
Inflammation- Cardinal Signs
- Rubor: redness
- Calor: warmth
-Tumor: swelling
Dolor: pain
The third line of defense against foreign invaders can be described as having _______
and _______
Specificity and Memory
A foreign molecule that causes a specific immune response is an ______
Antigen
___ cells are part of the humoral immunity and mature in the Bone Marrow
B cells
____ cells are part of the cell mediated immunity and mature in the thymyus
T cells
The most abundant class of antibodies in serum is
IgG
_____ cells secrete antibodies
Plasma
IgG
monomer= 80% highest number of antibodies
2 binding site
, IgA
dimer= 13% of antigen
4,2 biding site
IgM
pentamer=6%
10 biding site
Example of natural active immunity
chicken pox infection, followed by lifelong immunity
Example of natural passive immunity
breastfeeding or an antitoxin because the body receives fully formed immunoglobulins
and will not result in memory
In HIV infection
CD4 T- helper cells are attacked, disruption of cell mediated immunity
Tetanus differs from botulism in that
muscles cannot relax in tetanus, while muscles cannot contract in botulism.
Botulism caused by an
-exotoxin
- prevents the release of AcH resulting in faccid paralysis
Oral lesions called Koplik's spot are seen in patients with _____
measles
infectious mononucleosis (Epstein-Barr virus)
signs/ symptoms:
fatigue, sore throat, cervical lymphadenopathy, splenomegaly
Variant Cruetzfeldt-Jakob Disease (vCJD) is caused by ______
Prions
When bacteria flourish and grow in the bloodstream the conditioned is termed _____
Sepsis
If a person who has never been infected with human herpesvirus 3 comes in contact
with the fluid of shingle lesions, they will come down with ______
chickenpox
A bull's- eye rash at the site of a tick bite is associated with ___
Lyme disease
The causative agent of lyme disease is
Borrelia burgdorferi
Staphylococcus aureus can cause
MRSA impetigo, scalded syndrome and necrotizing fasciitis
Can food poisoning still occur after consuming a reheated pot of soup known to be
contaminated with staphylococcus aureus?
-G+ and clusters of grapes
- yes
Causative agent of ocular trachoma
Chlamydia trachomatis
Causative agent of pharyngitis
Streptococcus pyogenes
Untreated streptococcal pharyngitis can lead to the following complications
SOLUTIONS
Which lines of defense would be considered nonspecific and innate?
First line of defense
Second line of defense
Differentiate between components of first and second line defense
FIRST:Physical and Chemical barriers
SECOND: phagocytosis, inflammation, fever, antimicrobial proteins
FLOD: lysozome
is secreted in tears and saliva
What human body region is protected by fatty acids, acidic pH, lactic acid, and tough
cell barrier with its own normal biota?
skin
The sweat doud on skin and saliva in the mouth attributed to what line of defense?
First line
Eosinophils
attack parasitic helminths
Basophils
- make up less than .5% of circulating WBCs
- granules contain histamine
When monocytes migrate from the blood out to the tissues, they are transformed by
inflammatory mediators to develop into________
Macrophages
Inflammation- Cardinal Signs
- Rubor: redness
- Calor: warmth
-Tumor: swelling
Dolor: pain
The third line of defense against foreign invaders can be described as having _______
and _______
Specificity and Memory
A foreign molecule that causes a specific immune response is an ______
Antigen
___ cells are part of the humoral immunity and mature in the Bone Marrow
B cells
____ cells are part of the cell mediated immunity and mature in the thymyus
T cells
The most abundant class of antibodies in serum is
IgG
_____ cells secrete antibodies
Plasma
IgG
monomer= 80% highest number of antibodies
2 binding site
, IgA
dimer= 13% of antigen
4,2 biding site
IgM
pentamer=6%
10 biding site
Example of natural active immunity
chicken pox infection, followed by lifelong immunity
Example of natural passive immunity
breastfeeding or an antitoxin because the body receives fully formed immunoglobulins
and will not result in memory
In HIV infection
CD4 T- helper cells are attacked, disruption of cell mediated immunity
Tetanus differs from botulism in that
muscles cannot relax in tetanus, while muscles cannot contract in botulism.
Botulism caused by an
-exotoxin
- prevents the release of AcH resulting in faccid paralysis
Oral lesions called Koplik's spot are seen in patients with _____
measles
infectious mononucleosis (Epstein-Barr virus)
signs/ symptoms:
fatigue, sore throat, cervical lymphadenopathy, splenomegaly
Variant Cruetzfeldt-Jakob Disease (vCJD) is caused by ______
Prions
When bacteria flourish and grow in the bloodstream the conditioned is termed _____
Sepsis
If a person who has never been infected with human herpesvirus 3 comes in contact
with the fluid of shingle lesions, they will come down with ______
chickenpox
A bull's- eye rash at the site of a tick bite is associated with ___
Lyme disease
The causative agent of lyme disease is
Borrelia burgdorferi
Staphylococcus aureus can cause
MRSA impetigo, scalded syndrome and necrotizing fasciitis
Can food poisoning still occur after consuming a reheated pot of soup known to be
contaminated with staphylococcus aureus?
-G+ and clusters of grapes
- yes
Causative agent of ocular trachoma
Chlamydia trachomatis
Causative agent of pharyngitis
Streptococcus pyogenes
Untreated streptococcal pharyngitis can lead to the following complications