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PHARMACOKINETICS - Answer: Transmission of medication through
body once administered.
What the body does to the drug.
, PHARMACODYNAMICS - Answer: How the drug acts on cells, tissues, or
receptors to produce therapeutic or adverse effects
WHAT THE DRUG DOES TO THE BODY
PHARMACOKINETICS DRUG PROCESSES (4) - Answer: ADME:
ABSORPTION
DISTRIBUTION
METABOLISM
EXCRETION
ABSORPTION - Answer: Transmission of medication from site of
administration to bloodstream
ABSORPTION INFLUENCED BY - Answer: • Route of administration (IV
FASTEST / SUBQ>IM)
• Drug solubility & dissolution rate (FAT SOLUBLE DRUGS FASTER)
• Perfusion (MORE PERFUSION = FASTER)
• Body surface area / area of absorptive surface (HIGHER SA = HIGHER
ABSORPTION)
FIRST PASS EFFECT - Answer: Hepatic metabolism of the drug IN LIVER
before it reaches the systemic circulation
BASICALLY MOST DRUG BROKEN DOWN IN LIVER FIRST TIME TAKEN
BEFORE DOING ITS THING