QUESTIONS AND FULL SOLUTION UPDATED
◉ Which chemotherapeutic drug is commonly combined with
trimethoprim; inhibits dihydrofolate synthesis?
Answer: Sulfonamides
◉ Which chemotherapeutic drug is a beta-lactam antibiotic with 2
sites that can be chemically modified?
Answer: cephalosporin
◉ Which chemotherapeutic drug is an aminoglycoside; binds 30S
ribosome; must be given by injection?
Answer: streptomycin
◉ Which chemotherapeutic drug was the first major antibiotic used
on humans?
Answer: Sulfanilamide. Sulfanilamide was on the market by the late
1930s and Penicillin was in major use around 1943.
◉ Which chemotherapeutic drug is a macrolide which binds the 50S
ribosomal subunit?
Answer: Erythromycin
,◉ Which chemotherapeutic drug is a Disrupt nucleic acid synthesis
by inhibiting bacterial DNA gyrase?
Answer: Quinolones
◉ Which chemotherapeutic drug is a polypeptide antibiotic found in
topical ointments; kills group A strep?
Answer: Bacitracin
◉ Which chemotherapeutic drug is a polyene antifungal agent that
disrupts membrane permeability?
Answer: amphotericin B
◉ Which chemotherapeutic drug is an antiviral agent used to treat
herpes virus infections?
Answer: acyclovir
◉ Which chemotherapeutic drug causes "black hairy tongue" as a
side effect?
Answer: metronidazole
◉ Which chemotherapeutic drug is a quinolone that inhibits
prokaryotic DNA gyrase?
, Answer: ciprofloxacin
◉ Which chemotherapeutic drug inhibits DNA-directed RNA
polymerase; used to treat tuberculosis?
Answer: Rifampin
◉ Which chemotherapeutic drug is the most commonly used and
produced antibiotic in the world?
Answer: cephalosporin
◉ Which chemotherapeutic drug is an antiviral thymidine analog
used to treat HIV infection?
Answer: AZT azidothymidine
◉ Which chemotherapeutic drug is a genus of bacteria that produces
more useful antibiotics than any other; genera of fungi that produce
many useful antibiotics?
Answer: streptomyces
◉ What are the types of lymphocytes?
Answer: T cells (cytotoxic and T helper-1/T helper-2), B cells
(memory and effector)