Anemia | Q&A | Grade A | 100% Correct (Verified Answers)
Subject: Hematology - Anemia Classification and Laboratory Interpretation
Source: NR570 MidTerm Study Set - Latest 2026/2027 Blueprint
Format: Q&A Guide with Clinical Rationale | Evidence-Based Practice | Verified Accurate Solutions
Instructions: Each question includes the verified correct answer with normal values, classification criteria, and
initial testing strategies for anemia.
1: What is the normal range for female hemoglobin?
Correct Answer: 11.6-14.8 g/dL
1. Normal hemoglobin values vary by sex due to androgenic effects on erythropoiesis.
2. Women have lower levels due to menstrual blood loss and absence of testosterone stimulation.
3. Reference ranges may vary slightly by laboratory; values below normal indicate anemia.
2: What is the normal range for male hemoglobin?
Correct Answer: 13.6-16.9 g/dL
1. Testosterone stimulates erythropoietin production and red blood cell synthesis.
2. Men have higher hemoglobin (about 1-2 g/dL higher than women of same age).
3. Values below 13.6 in men indicate anemia regardless of symptoms.
3: What is the normal range for mean corpuscular volume (MCV)?
Correct Answer: 80-100 fL
1. MCV measures average red blood cell size for classifying anemias.
2. Values below 80 fL indicate microcytic anemia; above 100 fL indicates macrocytic anemia.
3. Normocytic anemia has MCV within normal range (80-100 fL).
4: What MCV value defines microcytic anemia?
Correct Answer: <80 fL
1. Microcytosis indicates impaired hemoglobin synthesis (iron deficiency, thalassemia).
2. Low MCV results from shortened RBC lifespan or defective globin/heme production.
3. Causes include iron deficiency, thalassemia, anemia of chronic disease, sideroblastic anemia.
5: What MCV value defines macrocytic anemia?
Correct Answer: >100 fL
1. Macrocytosis indicates impaired DNA synthesis causing enlarged RBCs.
2. Most common causes: B12 deficiency, folate deficiency, MDS, alcoholism.
3. MCV >100 fL requires investigation for megaloblastic anemia.
6: What are the normal MCHC (mean corpuscular hemoglobin concentration) values?
Correct Answer: 33-37 g/dL (or 33%–37%)
1. MCHC reflects hemoglobin amount per RBC volume; low MCHC indicates hypochromia.
2. Low MCHC accompanies microcytic anemias (iron deficiency, thalassemia).
3. Normal MCHC with low MCV suggests thalassemia trait; low MCHC suggests iron deficiency.