COMSAE Practice Questions And Correct
Answers (Verified Answers) 2026
DMARD drug for UC/Crohns/RA - CORRECT ANSWER -sulfasalazine
pulmonary effects of CF - CORRECT ANSWER -chronic bronchitis and bronchiectasis
osteoporosis affects what parts of bone? - CORRECT ANSWER -(spongy and ) trabecular bone
mass loss
imipramine - CORRECT ANSWER -TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block
alpha1)
viscerosomatic - CORRECT ANSWER -visceral disease --> somatic finding
loratidine vs ranitidine - CORRECT ANSWER -loratidine: 2nd gen H1 blocker, doesnt cross
BBB --> less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
,cells w RBCs inside - CORRECT ANSWER -entaemoba histolytica
which type of pneumothorax causes tracheal deviation to the contra side? - CORRECT
ANSWER -tension
intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels
- CORRECT ANSWER -AVM arteriovenous malformation
cavernous hemangioma - CORRECT ANSWER -benign tumor of liver, A/W VHL
anti-HepB surface antibody is only present in what pop - CORRECT ANSWER -recovered or
immunized
not in chronic or
proctalgia fugax - CORRECT ANSWER -levator ani syndrome
fasciculus is UMN or LMN lesion? - CORRECT ANSWER -LMN
ectopic gastric tissue - CORRECT ANSWER -meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
antibodies in hashimotos attacks - CORRECT ANSWER -thyroid peroxidase or
antithyroglobulin
,enlarged non tender thyroid
2 factors that influence starling curve - CORRECT ANSWER -x axis- preload (EDV)
y axis- stroke volume or CO
treatment for fibromyalgia - CORRECT ANSWER -TCA, SNRIs anticonvulsants
what blocks NE reuptake? - CORRECT ANSWER -TCA or SNRIs
possible complication of pagets bone disease - CORRECT ANSWER -osteocarcoma
what does Hct tell you? - CORRECT ANSWER -ratio of volume of RBCs compared to total
blood volume
probenecid - CORRECT ANSWER -inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
2 causes of SCID - CORRECT ANSWER -ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
lithiums effects on urination - CORRECT ANSWER -inhibits vasopression/ADH --> increased
urinary frequency
, infertility drug that can result in multiple fetuses - CORRECT ANSWER -clomiphene (clones-
multiple babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
AFP levels in down syndrome - CORRECT ANSWER -low
GI malformation A/W down syndrome - CORRECT ANSWER -Hirschprungs- congenital
aganglionic megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
myasthenia gravis associations - CORRECT ANSWER -thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
tx for tinea - CORRECT ANSWER -azoles
beta blockers for asthma - CORRECT ANSWER -none- even beta 1s can be nonselective at
higher doses
Answers (Verified Answers) 2026
DMARD drug for UC/Crohns/RA - CORRECT ANSWER -sulfasalazine
pulmonary effects of CF - CORRECT ANSWER -chronic bronchitis and bronchiectasis
osteoporosis affects what parts of bone? - CORRECT ANSWER -(spongy and ) trabecular bone
mass loss
imipramine - CORRECT ANSWER -TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block
alpha1)
viscerosomatic - CORRECT ANSWER -visceral disease --> somatic finding
loratidine vs ranitidine - CORRECT ANSWER -loratidine: 2nd gen H1 blocker, doesnt cross
BBB --> less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
,cells w RBCs inside - CORRECT ANSWER -entaemoba histolytica
which type of pneumothorax causes tracheal deviation to the contra side? - CORRECT
ANSWER -tension
intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels
- CORRECT ANSWER -AVM arteriovenous malformation
cavernous hemangioma - CORRECT ANSWER -benign tumor of liver, A/W VHL
anti-HepB surface antibody is only present in what pop - CORRECT ANSWER -recovered or
immunized
not in chronic or
proctalgia fugax - CORRECT ANSWER -levator ani syndrome
fasciculus is UMN or LMN lesion? - CORRECT ANSWER -LMN
ectopic gastric tissue - CORRECT ANSWER -meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
antibodies in hashimotos attacks - CORRECT ANSWER -thyroid peroxidase or
antithyroglobulin
,enlarged non tender thyroid
2 factors that influence starling curve - CORRECT ANSWER -x axis- preload (EDV)
y axis- stroke volume or CO
treatment for fibromyalgia - CORRECT ANSWER -TCA, SNRIs anticonvulsants
what blocks NE reuptake? - CORRECT ANSWER -TCA or SNRIs
possible complication of pagets bone disease - CORRECT ANSWER -osteocarcoma
what does Hct tell you? - CORRECT ANSWER -ratio of volume of RBCs compared to total
blood volume
probenecid - CORRECT ANSWER -inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
2 causes of SCID - CORRECT ANSWER -ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
lithiums effects on urination - CORRECT ANSWER -inhibits vasopression/ADH --> increased
urinary frequency
, infertility drug that can result in multiple fetuses - CORRECT ANSWER -clomiphene (clones-
multiple babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
AFP levels in down syndrome - CORRECT ANSWER -low
GI malformation A/W down syndrome - CORRECT ANSWER -Hirschprungs- congenital
aganglionic megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
myasthenia gravis associations - CORRECT ANSWER -thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
tx for tinea - CORRECT ANSWER -azoles
beta blockers for asthma - CORRECT ANSWER -none- even beta 1s can be nonselective at
higher doses
