High-Yield Clinical for COMSAE 115 Questions
And Correct Answers (Verified Answers) 2026
Subarachnoid hemorrhage - CORRECT ANSWER -Caused by rupture of a berry (saccular)
aneurysm.
Basilar skull fracture - CORRECT ANSWER -Characterized by 'Raccoon eyes' (periorbital
ecchymosis), CSF otorrhea, and Battle's sign.
G6PD deficiency - CORRECT ANSWER -Identified by bite cells and Heinz bodies on blood
smear, hemolytic anemia after fava bean ingestion.
Thyroid storm - CORRECT ANSWER -Occurs in a patient with hyperthyroidism who develops
fever, tachycardia, confusion, and vomiting after surgery.
Neural tube defect - CORRECT ANSWER -Main concern with elevated AFP in a pregnant
woman's amniotic fluid (e.g., spina bifida).
Hereditary spherocytosis - CORRECT ANSWER -Diagnosed with spherocytes, increased
osmotic fragility, and negative Coombs test.
Ankylosing spondylitis - CORRECT ANSWER -Associated with HLA-B27 positivity, low back
pain, and uveitis.
Ulnar nerve - CORRECT ANSWER -Affected in a patient with 'claw hand' deformity and loss of
sensation in the medial hand.
Left middle cerebral artery stroke - CORRECT ANSWER -Causes sudden onset unilateral
weakness, face droop, and expressive aphasia affecting Broca's area.
, Pyruvate kinase deficiency - CORRECT ANSWER -Leads to impaired glycolysis and
nonspherocytic hemolytic anemia.
Granulosa cell tumor - CORRECT ANSWER -Identified by 'soap bubble' appearance on ovarian
tumor histology.
Streptococcus pneumoniae - CORRECT ANSWER -Most likely pathogen in a patient with fever,
cough with rusty sputum, and lobar consolidation on CXR.
Pheochromocytoma - CORRECT ANSWER -Diagnosed in a young patient with episodic
palpitations, diaphoresis, hypertension, and elevated catecholamines.
Portal hypertension - CORRECT ANSWER -Cause of ascites with SAAG >1.1, low protein, and
history of liver disease.
Epiglottitis - CORRECT ANSWER -Characterized by 'thumb sign' on lateral neck X-ray and
patient drooling with stridor.
Acute respiratory distress syndrome (ARDS) - CORRECT ANSWER -Identified by 'ground-
glass' appearance on chest CT in a patient with diffuse alveolar damage.
Primary hyperaldosteronism (Conn's syndrome) - CORRECT ANSWER -Likely diagnosis in a
patient with hypokalemia, metabolic alkalosis, and hypertension.
Erythema nodosum - CORRECT ANSWER -Characterized by painful, raised, erythematous
nodules on anterior shins.
Toxoplasma gondii encephalitis - CORRECT ANSWER -Most likely diagnosis for a 'ring-
enhancing lesion' on brain MRI in an HIV patient.
And Correct Answers (Verified Answers) 2026
Subarachnoid hemorrhage - CORRECT ANSWER -Caused by rupture of a berry (saccular)
aneurysm.
Basilar skull fracture - CORRECT ANSWER -Characterized by 'Raccoon eyes' (periorbital
ecchymosis), CSF otorrhea, and Battle's sign.
G6PD deficiency - CORRECT ANSWER -Identified by bite cells and Heinz bodies on blood
smear, hemolytic anemia after fava bean ingestion.
Thyroid storm - CORRECT ANSWER -Occurs in a patient with hyperthyroidism who develops
fever, tachycardia, confusion, and vomiting after surgery.
Neural tube defect - CORRECT ANSWER -Main concern with elevated AFP in a pregnant
woman's amniotic fluid (e.g., spina bifida).
Hereditary spherocytosis - CORRECT ANSWER -Diagnosed with spherocytes, increased
osmotic fragility, and negative Coombs test.
Ankylosing spondylitis - CORRECT ANSWER -Associated with HLA-B27 positivity, low back
pain, and uveitis.
Ulnar nerve - CORRECT ANSWER -Affected in a patient with 'claw hand' deformity and loss of
sensation in the medial hand.
Left middle cerebral artery stroke - CORRECT ANSWER -Causes sudden onset unilateral
weakness, face droop, and expressive aphasia affecting Broca's area.
, Pyruvate kinase deficiency - CORRECT ANSWER -Leads to impaired glycolysis and
nonspherocytic hemolytic anemia.
Granulosa cell tumor - CORRECT ANSWER -Identified by 'soap bubble' appearance on ovarian
tumor histology.
Streptococcus pneumoniae - CORRECT ANSWER -Most likely pathogen in a patient with fever,
cough with rusty sputum, and lobar consolidation on CXR.
Pheochromocytoma - CORRECT ANSWER -Diagnosed in a young patient with episodic
palpitations, diaphoresis, hypertension, and elevated catecholamines.
Portal hypertension - CORRECT ANSWER -Cause of ascites with SAAG >1.1, low protein, and
history of liver disease.
Epiglottitis - CORRECT ANSWER -Characterized by 'thumb sign' on lateral neck X-ray and
patient drooling with stridor.
Acute respiratory distress syndrome (ARDS) - CORRECT ANSWER -Identified by 'ground-
glass' appearance on chest CT in a patient with diffuse alveolar damage.
Primary hyperaldosteronism (Conn's syndrome) - CORRECT ANSWER -Likely diagnosis in a
patient with hypokalemia, metabolic alkalosis, and hypertension.
Erythema nodosum - CORRECT ANSWER -Characterized by painful, raised, erythematous
nodules on anterior shins.
Toxoplasma gondii encephalitis - CORRECT ANSWER -Most likely diagnosis for a 'ring-
enhancing lesion' on brain MRI in an HIV patient.
