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ATI Med Surg Immune, Infection, Oncology & Cardiovascular Questions and Answers (500+ Q&A) | HIV, Tuberculosis, Cancer Care, Cardiac Disorders & NCLEX RN Review 2026

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This comprehensive ATI Medical-Surgical Nursing study guide contains over 500 expertly verified questions and answers covering major concepts in immune disorders, infection control, oncology nursing, hematologic disorders, and cardiovascular nursing. The document is designed to support nursing students preparing for ATI examinations, NCLEX-RN review, medical-surgical nursing assessments, and advanced clinical competency testing. Key topics include HIV/AIDS management, tuberculosis precautions, hepatitis, systemic lupus erythematosus (SLE), rheumatoid arthritis, Raynaud’s disease, infection prevention, cancer care, chemotherapy safety, radiation therapy, thrombocytopenia, anemia, heart failure, hypertension, myocardial infarction, vascular disorders, and emergency cardiac interventions. The material provides detailed scenario-based and NCLEX-style nursing questions that strengthen clinical judgment, prioritization, pharmacology knowledge, patient education, and evidence-based nursing interventions. The study guide emphasizes isolation precautions, oncology treatment complications, immune system disorders, medication administration, transfusion reactions, electrolyte imbalances, fluid volume disorders, and cardiovascular risk management. Multiple sections also focus on patient safety, therapeutic communication, postoperative care, palliative care, dietary management, and nursing care planning relevant to acute and chronic medical-surgical conditions. This resource is highly beneficial for Associate Degree Nursing (ADN), Bachelor of Science in Nursing (BSN), Practical Nursing (PN/LPN), and accelerated nursing students preparing for ATI examinations and NCLEX-RN licensure. It is also valuable for nursing remediation programs, nurse educators, healthcare review courses, and clinical practice preparation in medical-surgical nursing rotations. Students specializing in adult health nursing, oncology nursing, cardiovascular nursing, and infection control will find the content especially useful for strengthening exam readiness and clinical reasoning skills. The study material aligns closely with nursing concepts presented in widely used references such as Lewis’s Medical-Surgical Nursing, Brunner & Suddarth’s Textbook of Medical-Surgical Nursing, ATI RN Adult Medical Surgical Nursing Review Module, and Saunders Comprehensive Review for the NCLEX-RN Examination. The concepts also reflect evidence-based standards discussed in journals including the American Journal of Nursing, Journal of Clinical Nursing, Clinical Journal of Oncology Nursing, and Nursing2026. Keywords ATI med surg, ATI medical surgical nursing, NCLEX RN review, nursing questions and answers, oncology nursing, cardiovascular nursing, immune disorders nursing, infection control nursing, HIV nursing care, tuberculosis nursing, lupus nursing, rheumatoid arthritis nursing, chemotherapy nursing, radiation therapy nursing, cancer care nursing, cardiac nursing, heart failure nursing, hypertension nursing, myocardial infarction nursing, thrombocytopenia nursing, anemia nursing, hematology nursing, nursing pharmacology, isolation precautions, patient safety nursing, nursing care plans, adult health nursing, ATI RN review, med surg exam prep, clinical judgment nursing

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ATI MED SURG IMMUNE &
INFECTION, ATI MED SURG
ONCOLOGY, ATI MED SURG
CARDIOVASCULAR 2026
EXPERT VERIFED ACE THE
TEST



A nurse is caring for a male client who reports a thick urethral discharge.

Which of the following actions should the nurse take?

A. Contact the client's sexual partners

B. Obtain a urethral specimen for culture

,C. Prepare to administer penicillin to the client


D. Obtain blood for a rapid plasma reagin test - ANSWER ✔✔B.

Obtain a urethral specimen for culture

A home health nurse is planning care for a client who is receiving

chemotherapy and has neutropenia. Which of the following foods should

the nurse include in the client's plan of care?

A. Soft-boiled eggs

B. Brie cheese made with unpasteurized milk

C. Cold deli-meat sandwiches


D. Baked chicken - ANSWER ✔✔D. Baked chicken


A nurse is reviewing the laboratory results for a client who reports

bilateral pain and swelling in her finger joints, with stiffness in the

morning. The nurse should recognize that an increase in which of the

following laboratory values can indicate arthritis?

A. Reticulocyte count

B. Rheumatoid factor

C. Direct Coombs' test


D. Platelet count - ANSWER ✔✔B. Rheumatoid factor

,A nurse is providing discharge instructions to a male client who is being

treated for genital warts. Which of the following statements indicates that

the client understands how to prevent the transmission of this sexually

transmitted infection (STI)?

A. "I will bring my sexual partner for treatment."

B. "Now that I've had my first dose of medicine, I can resume sexual

activity."

C. "Once I have been treated, I don't have to use condoms anymore."

D. "Once treatment is complete and I am free of symptoms, I don't have

to return to the clinic." - ANSWER ✔✔A. "I will bring my sexual

partner for treatment."

A nurse is teaching a client who has AIDS about the transmission of

Pneumocystis jiroveci pneumonia (PCP). Which of the following pieces

of information should the nurse include in the teaching?

A. "PCP is sexually transmitted from person to person."

B. "You were most likely exposed to a contaminated surface such as a

drinking glass."

C. "PCP results from an impaired immune system."



3
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STATEMENT. ALL RIGHTS RESERVED

, D. "You might have contracted PCP from a family pet." - ANSWER

✔✔C. "PCP results from an impaired immune system."


A nurse is caring for client who has human immunodeficiency virus

(HIV). Which of the following types of isolation should the nurse

implement to prevent the transmission of HIV?

A. Protective isolation

B. Droplet precautions

C. Standard precautions


D. Airborne precautions - ANSWER ✔✔C. Standard precautions


A nurse is teaching a client who has Raynaud's disease. Which of the

following pieces of information should the nurse include in the teaching?

A. Protect against the cold by wearing layers of clothing

B. Begin an exercise program of 2-mile walks once per week

C. Increase vitamin A in the diet


D. Elevate the hands above heart level when resting - ANSWER

✔✔A. Protect against the cold by wearing layers of clothing

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