NR 603 WEEK 7: TEST QUESTIONS WITH CORRECT
ANSWERS
1) Circulating immune complexes with antibody against DNA are deposited into the
basement membranes of capillaries in the -- Answer ✔✔ kidney, heart, skin,
brain and joints these complexes trigger inflammation that causes tissue
destruction
2) overaggressive autoimmune response are also related to -- Answer ✔✔
activation of B and T cells. Specific disease effects depends on the involved cell
types or organs
3) Clinical manifestations and complications -- Answer ✔✔ severity of SLE is
variable, ranges from relatively mild to rapidly progressive affecting many body
systems. no characteristic pattern occurs in the progressive involvement of SLE.
4) any organ can be affected by circulating immune complexes the most common
affected tissues are -- Answer ✔✔ the skin and muscle, lining of the lungs, heart,
nervous tissue, and kidneys.
, 5) what are some general complaints of SLE -- Answer ✔✔ fever, weight loss, joint
pain (arthralgia) and excessive fatigue may proceed worsened disease activity
6) Dermatologic Problems -- Answer ✔✔ *vascular lesions ( develop on sun-
exposed areas)
*Sunlight (photosensitivity)
*butterfly rash over cheeks and bridge of nose
*discoid (round, coin shaped) lesions
*oral or nasopharyngeal ulcers
*alopecia is common with or without scalp related lesions. Hair may grow back
during remission but may remain permanent over lesions.
*scalp becomes dry, scaly and atrophies
7) musculoskeletal problems -- Answer ✔✔ *arthritis 95%
*pain in multiple joints (polyarthralgia) with morning stiffness is often first
complaint
*diffuse swelling occurs with joint and muscle pain
*lupus-related arthritis is usually nonerosive but may cause deformities( swan
neck of fingers, *ulnar deviation, subluxation with joint laxity)
*patients with SLE have increased risk of bone loss and fracture
8) Cardiopulmonary Problems -- Answer ✔✔ *Tachypnea and cough (presents lung
disease)
*Pleurisy
*dysthymias (due to fibrosis of SA and AV node)
*Pericarditis
*secondary antiphospholipid syndrome( disorder of coagulation leading to clots in
the arteries and veins with related risk of stroke, gangrene, and heart attack)
9) Renal problems -- Answer ✔✔ *75% experience kidney damage
usually evident by 2nd year of diagnosis
*may result from mild proteinuria to rapidly *progressive glomerulonephritis.
*scaring and permanent damage can lead to end-stage-renal failure disease( ERSD)
ANSWERS
1) Circulating immune complexes with antibody against DNA are deposited into the
basement membranes of capillaries in the -- Answer ✔✔ kidney, heart, skin,
brain and joints these complexes trigger inflammation that causes tissue
destruction
2) overaggressive autoimmune response are also related to -- Answer ✔✔
activation of B and T cells. Specific disease effects depends on the involved cell
types or organs
3) Clinical manifestations and complications -- Answer ✔✔ severity of SLE is
variable, ranges from relatively mild to rapidly progressive affecting many body
systems. no characteristic pattern occurs in the progressive involvement of SLE.
4) any organ can be affected by circulating immune complexes the most common
affected tissues are -- Answer ✔✔ the skin and muscle, lining of the lungs, heart,
nervous tissue, and kidneys.
, 5) what are some general complaints of SLE -- Answer ✔✔ fever, weight loss, joint
pain (arthralgia) and excessive fatigue may proceed worsened disease activity
6) Dermatologic Problems -- Answer ✔✔ *vascular lesions ( develop on sun-
exposed areas)
*Sunlight (photosensitivity)
*butterfly rash over cheeks and bridge of nose
*discoid (round, coin shaped) lesions
*oral or nasopharyngeal ulcers
*alopecia is common with or without scalp related lesions. Hair may grow back
during remission but may remain permanent over lesions.
*scalp becomes dry, scaly and atrophies
7) musculoskeletal problems -- Answer ✔✔ *arthritis 95%
*pain in multiple joints (polyarthralgia) with morning stiffness is often first
complaint
*diffuse swelling occurs with joint and muscle pain
*lupus-related arthritis is usually nonerosive but may cause deformities( swan
neck of fingers, *ulnar deviation, subluxation with joint laxity)
*patients with SLE have increased risk of bone loss and fracture
8) Cardiopulmonary Problems -- Answer ✔✔ *Tachypnea and cough (presents lung
disease)
*Pleurisy
*dysthymias (due to fibrosis of SA and AV node)
*Pericarditis
*secondary antiphospholipid syndrome( disorder of coagulation leading to clots in
the arteries and veins with related risk of stroke, gangrene, and heart attack)
9) Renal problems -- Answer ✔✔ *75% experience kidney damage
usually evident by 2nd year of diagnosis
*may result from mild proteinuria to rapidly *progressive glomerulonephritis.
*scaring and permanent damage can lead to end-stage-renal failure disease( ERSD)
