Cognitive Function - Answers the process whereby an individual is able to perceive, recognize and
understand thoughts and ideas
- concentrating
- language
- self regulation
Normal Changes in Cognitive Function with Age - Answers - Slower behavior and reaction time
- attention, language, thinking and planning processes disrupted
- memory processes disrupted
* recent memory, spatial memory and memory of faces
Normal Anatomical Changes with Age - Answers - Frontal and Temporal lobe atrophy
* loss of dendrites, and synapses NOT neurons
- Brain weight decreases
* gray and white matter loss
* ventricles increase
Normal Age-Related Changes - Answers - making a bad decision once in a while
- missing a monthly payment
- sometimes forgetting which word to use
Sign's of Dementia - Answers - poor judgement
- inability to manage a budget
- losing track of the date or the season
Alzheimer's Disease (AD) - Answers - most common form of dementia
* loss of cognitive function and behavioral abilities
- prodromal phase known as Mild Cognitive Impairment (MCI)
- Symptoms arise in the late 60's
- Irreversible & progressive neurodegenerative disease
- 6th leading cause of death in American >65 yrs
Hallmarks of Alzheimer's Disease - Answers - beta amyloid plaques
- tau neurofibrillary tangles
- cell death (atrophy)
- acetylcholine deficits
William Utermohlen: Art and Alzheimer's Disease - Answers The artist was diagnosed with
Alzheimer's Disease in 1995 and spent 12 years trying to understand the disease by painting self
portraits; clearly showing his cognitive decline
Longitudinal Study: Rolland 2008 - Answers 20 of 24 studies showed significant protective effect of PA
against cognitive decline or dementia
Longitudinal Study: Bowen 2012 - Answers Older adults reporting greater vigorous housework in
previous 3-7 years had lower risk of dementia
Longitudinal Study: Buchman 2012 - Answers Higher levels of PA measured with actigraph for 10 days
associated with reduced Alzheimer's Disease risk ( 4 year average follow up)
Intervention Study: Lautneschlager 2008 - Answers 138 older adults with MCI or memory complaints
randomized to 6 months self-directed PA program
Intervention Study: Baker 2010 - Answers 6 months aerobic exercise (vs. stretching control) improved
executive function but not declarative memory in OA's with MCI
Intervention Study: Winchester 2013 - Answers 1 year regular walking (vs. sedentary control) led to
attenuations in global cognitive decline in patients with mild to moderate Alzheimer's Disease
Exercise Post Stroke - Answers - 38 stroke survivors = 8 weeks of aerobic exercise 3 times a week for
45 minutes
- Motor learning improved in affected and unaffected sides
- information processing speed improved
task accuracy improved
Standard Population - Answers - 101 under-active or sedentary individuals without cognitive
impairment
- 4 groups: No-change control, 75, 150, 225 minutes per week of MI aerobic exercise for 26 weeks
- Simple attention improved across all exercise groups
- Dose-response relationship with Visuospatial Processing
, - Greater Fitness Improvements = Greater cognitive gains
Does exercise improve cognitive function? - Answers - Yes, but the effect is small
- when accumulated over weeks and months, large positive effect
Neuroplasticity - Answers the brain's ability to adapt to a changing environment and remodel itself
throughout the lifespan
Neurogenesis - Answers birth of new neurons in the adult hippocampus
- down-regulated in advanced age
Synaptic Plasticity - Answers exercise can make existing synapses STRONGER and help build MORE
synapses
Brain Derived Neurotrophic Factor (BDNF) - Answers Key growth factor; plays a role in both synaptic
plasticity AND neurogenesis
Improved Peripheral Metabolic Functioning - Answers Exercise improves body composition, glucose
tolerance, insulin sensitivity, blood pressure, blood lipid levels, less inflammation/oxidative stress
-brain and body impact each other
School-Based Physical Education Studies - Answers Increased time spent in PE appears to have a
positive relationship or no relationship with academics, NOT a negative relationship
Recess Studies - Answers time spent in recess appears to have a positive relationship or no
relationship with attention, concentration and/or on-task classroom behaviors
Classroom Physical Activity Studies - Answers Postive Associations
Extracurricular Physical Activity Studies - Answers Positive or Neutral Associations
Academics and Physical Activity - Answers - general positive association
- more fit = better academic performance
Which part of the brain benefits the most from exercise? - Answers improved neuroplasticity
Executive Functioning - Answers processes that control cognitive functions toward goal-oriented
behavior
- scheduling
- planning
- multi tasking
Supported largely by prefrontal cortex
Components of Executive Functioning - Answers - Flexibility (shifting)
- Working memory (monitoring and updating)
- Inhibition (of distractions, of impulses)
Flexibility - Answers - ability to change perspectives
- think outside the box
- admit you're wrong
- take advantage of sudden opportunities
Working Memory - Answers - holding information in mind and being able to work with it
- important for-
* linguistics
* understanding cause and effect
* understanding concepts
Inhibition - Answers - controlling one's behavior
- controlling attention
- children with lower inhibition grow up to have-
* worse health
* more crimes
* less happy
Importance of Executive Functions - Answers - Children with higher executive functions do better in
school and on standardized tests
- Physical Activity can improve executive functions in children
Mechanism: Physio - - Answers - increased brain-derived neurotrophic factor (BDNF)
- Hippocampal Neurogenesis
- Increased catecholamine levels (increased arousal)
Mechanism: Psych- - Answers - improved self-esteem
- improved self-efficacy
Mechanism: Other- - Answers - reduced obesity
- improved sleep