OBGYN COMAT Review EXAM || MOST RECENT
EXAM 2026-2027 ACTUAL COMPLETE REAL EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED
ANSWERS) ALREADY GRADED A+ | GUARANTEED
SUCCESS!! BRAND NEW!! JUST RELEASED!!
What's the definition of primary amenorrhea? - ANSWER-
Absence of menses
by age 16 w/secondary sexual development
present...
Or the absence of secondary sexual
characteristics by age 14
What are the major causes of absence of secondary sexual
characteristics in primary amenorrhea? - ANSWER-Absent
secondary sexual characteristics= no estrogen production... -
constitutional growth delay
-primary ovarian insufficiency (most commonly Turners)
-Central hypogonadism
Differential for primary amenorrhea with presence of secondary
sexual characteristics? - ANSWER-Primary amenorrhea
w/secondary sex characteristics= estrogen production but
other anatomic or genetic problems...
-Mullerian agenesis (absence of 2/3 of vagina & uterine
abnormalities)
-Imperforate hymen
,-Complete androgen insensitivity
how do patients present w/complete androgen insensitivity? -
ANSWER-Breast
development (aromatization of testosterone to estrogen) but are
amenorrheic &
lack pubic
hair.
How to diagnose someone w/primary amenorrhea? - ANSWER-
1. Get a pregnancy test!
2. Obtain bone age radiograph (to evaluate constitutional
growth delay etc)
3. Ultrasound to evaluate ovaries
4. If normal breast development but no uterus- get karyotype to
evaluate for androgen insensitivity syndrome (XY)
5. If normal breast development WITH uterus- measure
prolactin & get MRI to
assess pituitary
gland.
Interpretation of bone radiographs in setting of primary
amenorrhea? - ANSWER-If pt is of short statue (bone age <12
yrs) but normal growth velocity= constitutional growth delay
If bone age is >12 yrs but still no signs of puberty, get
LH/FSH levels to
evaluate where on HPA axis the
problem is.
,Definition of secondary amenorrhea - ANSWER-absence of
menses for 6
consecutive months in women who have
passed menarche.
Diagnosis of secondary amenorrhea - ANSWER-1. get
pregnancy test 2. if - pregnancy test, measure TSH &
prolactin (note: increased prolactin inhibits release of LH
& FSH). 3. Initiate a progestin challenge
4. If signs of hyperglycemia or hypotension: do 1mg overnight
dexamethasone suppression test to distinguish CAH,
Cushing's, & Addison's. 5. If clinical virilization: measure
testosterone, DHEAS, & 17hydroxyprogesterone. (mild
pattern= PCOS, CAH or Cushing's)...(moderate to severe=
look for ovarian or adrenal tumor).
How can thyroid affect puberty? - ANSWER-Precocious
puberty can occur in
response to chronic hypothyroidism bc high TSH
stimulates LH & FSH
receptors (they all share the same
alpha subunit)
What secretes bhCG & why? - ANSWER-Endometrium if the egg
is fertilized &
implanted-> hCG is secreted to maintain the corpus luteum
(which secretes
, estradiol & progesterone to mainain the endometrium & induce
development of
secretory ducts)....corpus luteum continues to secrete
progesterone until
placenta can secrete enough (~8-12
weeks).
What's Asherman syndrome & treatment - ANSWER-Scarring of
the uterus that
follows infection or postpartum
infection.
Tx= lysis of adhesions & estrogen administration
Next step in an XY patient with androgen insensitivity syndrome
& testicles - ANSWER-Remove the testicles at an early age bc
of increased risk of testicular cancer
Next step if a pt has primary amenorrhea w/secondary sexual
characteristics - ANSWER-Exam, ultrasound & genetic analysis
to look for abnormal anatomy or
XY genotype
Next step if pt has primary amenorrhea but no secondary sexual
characteristics
- ANSWER-Measure
LH/FSH...
High= gonadal agenesis or dysgenesis, or ovarian failure
EXAM 2026-2027 ACTUAL COMPLETE REAL EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED
ANSWERS) ALREADY GRADED A+ | GUARANTEED
SUCCESS!! BRAND NEW!! JUST RELEASED!!
What's the definition of primary amenorrhea? - ANSWER-
Absence of menses
by age 16 w/secondary sexual development
present...
Or the absence of secondary sexual
characteristics by age 14
What are the major causes of absence of secondary sexual
characteristics in primary amenorrhea? - ANSWER-Absent
secondary sexual characteristics= no estrogen production... -
constitutional growth delay
-primary ovarian insufficiency (most commonly Turners)
-Central hypogonadism
Differential for primary amenorrhea with presence of secondary
sexual characteristics? - ANSWER-Primary amenorrhea
w/secondary sex characteristics= estrogen production but
other anatomic or genetic problems...
-Mullerian agenesis (absence of 2/3 of vagina & uterine
abnormalities)
-Imperforate hymen
,-Complete androgen insensitivity
how do patients present w/complete androgen insensitivity? -
ANSWER-Breast
development (aromatization of testosterone to estrogen) but are
amenorrheic &
lack pubic
hair.
How to diagnose someone w/primary amenorrhea? - ANSWER-
1. Get a pregnancy test!
2. Obtain bone age radiograph (to evaluate constitutional
growth delay etc)
3. Ultrasound to evaluate ovaries
4. If normal breast development but no uterus- get karyotype to
evaluate for androgen insensitivity syndrome (XY)
5. If normal breast development WITH uterus- measure
prolactin & get MRI to
assess pituitary
gland.
Interpretation of bone radiographs in setting of primary
amenorrhea? - ANSWER-If pt is of short statue (bone age <12
yrs) but normal growth velocity= constitutional growth delay
If bone age is >12 yrs but still no signs of puberty, get
LH/FSH levels to
evaluate where on HPA axis the
problem is.
,Definition of secondary amenorrhea - ANSWER-absence of
menses for 6
consecutive months in women who have
passed menarche.
Diagnosis of secondary amenorrhea - ANSWER-1. get
pregnancy test 2. if - pregnancy test, measure TSH &
prolactin (note: increased prolactin inhibits release of LH
& FSH). 3. Initiate a progestin challenge
4. If signs of hyperglycemia or hypotension: do 1mg overnight
dexamethasone suppression test to distinguish CAH,
Cushing's, & Addison's. 5. If clinical virilization: measure
testosterone, DHEAS, & 17hydroxyprogesterone. (mild
pattern= PCOS, CAH or Cushing's)...(moderate to severe=
look for ovarian or adrenal tumor).
How can thyroid affect puberty? - ANSWER-Precocious
puberty can occur in
response to chronic hypothyroidism bc high TSH
stimulates LH & FSH
receptors (they all share the same
alpha subunit)
What secretes bhCG & why? - ANSWER-Endometrium if the egg
is fertilized &
implanted-> hCG is secreted to maintain the corpus luteum
(which secretes
, estradiol & progesterone to mainain the endometrium & induce
development of
secretory ducts)....corpus luteum continues to secrete
progesterone until
placenta can secrete enough (~8-12
weeks).
What's Asherman syndrome & treatment - ANSWER-Scarring of
the uterus that
follows infection or postpartum
infection.
Tx= lysis of adhesions & estrogen administration
Next step in an XY patient with androgen insensitivity syndrome
& testicles - ANSWER-Remove the testicles at an early age bc
of increased risk of testicular cancer
Next step if a pt has primary amenorrhea w/secondary sexual
characteristics - ANSWER-Exam, ultrasound & genetic analysis
to look for abnormal anatomy or
XY genotype
Next step if pt has primary amenorrhea but no secondary sexual
characteristics
- ANSWER-Measure
LH/FSH...
High= gonadal agenesis or dysgenesis, or ovarian failure
