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Pharmacology High-Yield Exam Questions & Answers Drugs, Mechanisms & Side Effects Nursing Revision (2026)

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This high-yield Pharmacology revision guide contains 50 of the most frequently tested exam questions and answers covering essential drug classes, mechanisms of action, therapeutic uses, and key side effects. Designed for nursing, medical, pharmacy, and allied health students, this resource focuses on the core pharmacology concepts that repeatedly appear in exams worldwide. Each question is structured for fast recall, clinical understanding, and exam success, making it ideal for both last-minute revision and long-term study preparation.

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50 High-Yield Pharmacology Questions & Answers

1. What is the mechanism of action of paracetamol?

Answer: Inhibits prostaglandin synthesis in the CNS (analgesic & antipyretic effect).

2. Main side effect of paracetamol overdose?

Answer: Liver toxicity (hepatotoxicity).

3. Mechanism of NSAIDs?

Answer: Inhibit COX-1 and COX-2 enzymes.

4. Major side effect of NSAIDs?

Answer: Gastric ulcers and bleeding.

5. Aspirin mechanism?

Answer: Irreversibly inhibits COX enzymes.

6. Main side effect of aspirin?

Answer: Bleeding tendency.

7. Heparin mechanism?

Answer: Activates antithrombin III → inhibits clotting factors.

8. Warfarin mechanism?

Answer: Inhibits vitamin K-dependent clotting factors.

9. Warfarin antidote?

Answer: Vitamin K.

, 10. Heparin antidote?

Answer: Protamine sulfate.

11. Beta-blockers' mechanism?

Answer: Block beta-adrenergic receptors → reduce heart rate and BP.

12. Side effects of beta-blockers?

Answer: Bradycardia.

13. ACE inhibitors mechanism?

Answer: Block conversion of angiotensin I to II.

14. Side effects of ACE inhibitors?

Answer: Dry cough.

15. Calcium channel blockers mechanism?

Answer: Block calcium entry into cardiac and smooth muscle.

16. Side effects of calcium channel blockers?

Answer: Hypotension and edema.

17. Diuretics mechanism?

Answer: Increase urine output by acting on the kidneys.

18. Loop diuretics example?

Answer: Furosemide.

19. Side effects of loop diuretics?

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