Advanced Pharmacology for Care of Family | 200+ Q&A |
Grade A | 100% Correct Verified Answers
Subject: Advanced Pharmacology – STI Treatment (Chlamydia, Gonorrhea, Bacterial Vaginosis, HSV,
Trichomoniasis, Syphilis, PID); BPH Medications (Doxazosin, Dutasteride, Terazosin); Hormonal
Therapies (Progesterone, Progestin, Testosterone, Medroxyprogesterone Acetate); Erectile Dysfunction
(Alprostadil, Papaverine/Phentolamine); Neurology (Parkinson's Disease – Pramipexole,
Levodopa/Carbidopa, COMT Inhibitors, Bromocriptine; Alzheimer's Disease – Rivastigmine, Donepezil,
Memantine; Seizure Disorders – Phenytoin, Lamotrigine, Anticonvulsant/OC Interactions); Migraine
(Preventative – Beta-Blockers; Abortive – NSAIDs, Triptans, Sumatriptan); Psychiatry (Panic Disorder,
GAD, Performance Anxiety – SSRIs, SNRIs, Buspirone; Depression – Treatment failure, Black Box
Warning; Insomnia – Benzodiazepines, Z-Drugs, Melatonin Agonists; Bipolar – Lithium (Therapeutic
Range, Interactions); Antipsychotics (First-Generation EPS, Second-Generation Metabolic); MAOIs
(Hypertensive Crisis, Tyramine); SSRIs (Adverse Effects, Serotonin Syndrome); CAM (Kava, Ginkgo
Biloba, Ginger, St. John's Wort, Echinacea, Flaxseed, Coenzyme Q-10, Feverfew); Regulatory Acts
(DSHEA 1994, FD&C Act, DSNDCPA 2006, CGMP 2007).
Source: NR 566 Final Exam Blueprint 2024-2025, CDC STI Guidelines, AAN, APA, FDA, NCCIH.
Format: Q&A Guide with Clinical Rationale | Verified Answers | Grade A Guaranteed
What is the first line treatment for Chlamydia that only needs to be taken orally once?
Correct Answer: Azithromycin 1000mg (1g) single dose.
1. Azithromycin 1g PO once is effective for uncomplicated urogenital chlamydia. Alternative: doxycycline
100mg BID x7 days (preferred in pregnancy).
2. Test of cure not routinely required unless pregnant or symptoms persist (repeat 4 weeks after
treatment). Treat sexual partners.
What is the first line treatment for Chlamydia that is taken BID for 7 days?
Correct Answer: Doxycycline 100mg BID for 7 days.
1. Doxycycline has slightly higher efficacy than azithromycin (97% vs 95%). Avoid in pregnancy
(teratogenic).
2. Educate: take with food (GI upset), avoid milk/antacids within 2 hours, no sun exposure
(photosensitivity).
What is the IM treatment for uncomplicated gonorrhea?
Correct Answer: Ceftriaxone 500mg IM (weight-based: 500mg for <150kg; 1g for ≥150kg).
1. Dual therapy with ceftriaxone IM plus doxycycline 100mg BID x7 days recommended (cover chlamydia
co-infection).
2. Alternative: cefixime 800mg PO (less preferred due to resistance).
, IM ceftriaxone can be given with or without this medication to treat gonorrhea.
Correct Answer: Doxycycline 100mg BID for 7 days.
1. Co-infection with chlamydia common; dual therapy also reduces resistance.
2. If chlamydia excluded (NAAT negative), ceftriaxone alone may be sufficient.
Treatment for bacterial vaginosis in a non-pregnant patient.
Correct Answer: Metronidazole 500mg BID for 7 days (oral) OR metronidazole 0.75% vaginal gel
once daily x5 days OR clindamycin 2% vaginal cream x7 days.
1. Metronidazole: avoid alcohol (disulfiram reaction).
2. Tinidazole 2g PO once (single dose) alternative.
What are two treatments for bacterial vaginosis in a pregnant patient?
Correct Answer: Vaginal metronidazole 0.75% gel for 7 days OR clindamycin 2% cream for 7 days
(oral metronidazole also acceptable).
1. CDC guidelines: oral metronidazole 500mg BID x7 days safe in pregnancy (category B).
2. Treat symptomatic pregnant patients only (screening not routine).
First line treatment for HSV (initial episode).
Correct Answer: Acyclovir 400mg three times a day for 7-10 days (or valacyclovir 1g BID x7-10 days,
or famciclovir 250mg TID x7-10 days).
1. Second line: acyclovir 800mg BID for 5 days (recurrent episode).
2. Suppressive therapy: valacyclovir 500-1000mg daily for frequent recurrences (>9/year).
Trichomoniasis treatment for women.
Correct Answer: Metronidazole 500mg BID for 7 days OR tinidazole 2g single dose.
1. Tinidazole single dose has better gastrointestinal tolerability and higher cure rate.
2. Treat sexual partners simultaneously.
Trichomoniasis treatment for men.
Correct Answer: Metronidazole 2g single dose OR tinidazole 2g single dose.
1. Asymptomatic men often carriers. Treat all partners to prevent reinfection.
What are doxazosin side effects?
Correct Answer: Hypotension, dizziness, nasal congestion, fatigue, headache, orthostatic
hypotension (risk of syncope with first dose).
1. Doxazosin is an alpha-1 blocker for BPH. First dose should be taken at bedtime to minimize
orthostatic hypotension.
2. Also used off-label for hypertension.