NR 565 PHARMACOLOGY WEEK 1
UPDATE|EXAM
QUESTIONS WITH MULTIPLE
CHOICES |VERIFIED & REVISED
ANSWERS (NEW)!!!
Pharmacokineticsm-
mCORRECTmANSWERmThemstudymofmdrugmabsorption,mdistribution,mmetabolism,mandmexcretionminm
thembody
"Whatmthembodymdoesmtomthemdrug"
Factorsmthatmaffectmdrugmabsorptionm(5)m-mCORRECTmANSWERmRatemofmdissolution
Surfacemarea
Bloodmflow
Lipidmsolubility
PHmpartitioning
Factorsmthatmaffectmdrugmdistributionm(4)m-mCORRECTmANSWERmBloodmflowmtomtissues
Abilitymtomexitmvascularmsystem
Blood-brainmbarrier
Protein-bindingmcapacity
Pharmacodynamicsm-
mCORRECTmANSWERmThemstudymofmbiochemicalmandmphysiologicmeffectsmofmdrugsmonmthembodyma
ndmthemmolecularmmechanismsmbymwhichmthosemeffectsmaremproduced
"Whatmthembodymdoesmtomthemdrug"
Phamacodynamics:m3mmechanismsmofmactionm-mCORRECTmANSWERmReceptor
,Enzyme
Non-selectiveminteractionsm(i.e.mchemo)
Typesmofmdrugmtherapym(7)m-mCORRECTmANSWERmAcute
Maintenancem(HTN/bc)
Supplementalm(insulin)
Palliative
Supportivem(IVmfluid)
Prophylactic
Empiricalm(broad-spectrummabx)
IdiosyncraticmEffectm-mCORRECTmANSWERmUnexpectedmresponsemtommedication
Tolerancem-mCORRECTmANSWERmDecliningmresponsemtomamdrug
Dependencem-
mCORRECTmANSWERmPhysiological/psychologicalmneedmformamdrug;mneedsmdrugmformnormalmfunct
ion
Addictionm-mCORRECTmANSWERmCompulsivemusemofmamdrugmdespitemnegative/dangerousmeffects
Drugminteractions:mdrug-drugm-
mCORRECTmANSWERmWhenm2mdrugsmcompetemformmetabolizingmenzymes
Drugminteractions:mfood-drugm-mCORRECTmANSWERmGrapefruitmjuicemormleafymgreens
Drugminteractions:madditivem-mCORRECTmANSWERm1+1m=m2;mbothmprovidemintendedmeffect
, Drugminteractions:mantagonisticm-
mCORRECTmANSWERm1+1m=m<2;mlessmthanmdesiredmeffectmofmonemormbothmdrugs
Drugminteractions:msynergisticm-
mCORRECTmANSWERm1+1m=m>2;msummtotalmeffectmismgreatermthanmifmgivenmalonem(i.e.mlisinoprilm+m
HCTZ)
Drugminteractions:mincompatibilitym-
mCORRECTmANSWERm1+1mdoesmnotmequalm2;mtwomIVmdrugsmgivenmtogethermcausingmdecompositio
nmofmonemormbothmdrugs
8mrightsmofmmedicationmadministrationm-mCORRECTmANSWERmPatient
Medication
Dose
Route
Time
Reason
Responsem
Documentation
Adversemreactions:mpharmacologicm-mCORRECTmANSWERmExtensionmofmamdrug'smnormalmeffect
Adversemreactions:mAllergic/hypersensitivitym-
mCORRECTmANSWERmExaggeratedmimmunemresponsem(i.e.mmildmitchingmtomanaphylaxis)
Adversemreactions:midiosyncraticm-mCORRECTmANSWERmPeculiarmtomthempatient
UPDATE|EXAM
QUESTIONS WITH MULTIPLE
CHOICES |VERIFIED & REVISED
ANSWERS (NEW)!!!
Pharmacokineticsm-
mCORRECTmANSWERmThemstudymofmdrugmabsorption,mdistribution,mmetabolism,mandmexcretionminm
thembody
"Whatmthembodymdoesmtomthemdrug"
Factorsmthatmaffectmdrugmabsorptionm(5)m-mCORRECTmANSWERmRatemofmdissolution
Surfacemarea
Bloodmflow
Lipidmsolubility
PHmpartitioning
Factorsmthatmaffectmdrugmdistributionm(4)m-mCORRECTmANSWERmBloodmflowmtomtissues
Abilitymtomexitmvascularmsystem
Blood-brainmbarrier
Protein-bindingmcapacity
Pharmacodynamicsm-
mCORRECTmANSWERmThemstudymofmbiochemicalmandmphysiologicmeffectsmofmdrugsmonmthembodyma
ndmthemmolecularmmechanismsmbymwhichmthosemeffectsmaremproduced
"Whatmthembodymdoesmtomthemdrug"
Phamacodynamics:m3mmechanismsmofmactionm-mCORRECTmANSWERmReceptor
,Enzyme
Non-selectiveminteractionsm(i.e.mchemo)
Typesmofmdrugmtherapym(7)m-mCORRECTmANSWERmAcute
Maintenancem(HTN/bc)
Supplementalm(insulin)
Palliative
Supportivem(IVmfluid)
Prophylactic
Empiricalm(broad-spectrummabx)
IdiosyncraticmEffectm-mCORRECTmANSWERmUnexpectedmresponsemtommedication
Tolerancem-mCORRECTmANSWERmDecliningmresponsemtomamdrug
Dependencem-
mCORRECTmANSWERmPhysiological/psychologicalmneedmformamdrug;mneedsmdrugmformnormalmfunct
ion
Addictionm-mCORRECTmANSWERmCompulsivemusemofmamdrugmdespitemnegative/dangerousmeffects
Drugminteractions:mdrug-drugm-
mCORRECTmANSWERmWhenm2mdrugsmcompetemformmetabolizingmenzymes
Drugminteractions:mfood-drugm-mCORRECTmANSWERmGrapefruitmjuicemormleafymgreens
Drugminteractions:madditivem-mCORRECTmANSWERm1+1m=m2;mbothmprovidemintendedmeffect
, Drugminteractions:mantagonisticm-
mCORRECTmANSWERm1+1m=m<2;mlessmthanmdesiredmeffectmofmonemormbothmdrugs
Drugminteractions:msynergisticm-
mCORRECTmANSWERm1+1m=m>2;msummtotalmeffectmismgreatermthanmifmgivenmalonem(i.e.mlisinoprilm+m
HCTZ)
Drugminteractions:mincompatibilitym-
mCORRECTmANSWERm1+1mdoesmnotmequalm2;mtwomIVmdrugsmgivenmtogethermcausingmdecompositio
nmofmonemormbothmdrugs
8mrightsmofmmedicationmadministrationm-mCORRECTmANSWERmPatient
Medication
Dose
Route
Time
Reason
Responsem
Documentation
Adversemreactions:mpharmacologicm-mCORRECTmANSWERmExtensionmofmamdrug'smnormalmeffect
Adversemreactions:mAllergic/hypersensitivitym-
mCORRECTmANSWERmExaggeratedmimmunemresponsem(i.e.mmildmitchingmtomanaphylaxis)
Adversemreactions:midiosyncraticm-mCORRECTmANSWERmPeculiarmtomthempatient
