NR565: WEEK 5: ENDOCRINE: TEST QUESTIONS WITH CORRECT ANSWERS.

NR565: WEEK 5: ENDOCRINE: TEST QUESTIONS WITH CORRECT
ANSWERS.




1) In patients with liver dysfunction, metabolism of repaglinide may be slow; the risk
of hypoglycemia may be increase. Because of possible hypoglycemia, it is
imperative that patients eat no later than ____ minutes after taking the drug --
Answer ✔✔ 30 minutes



2) To start insulin, patients should be started on: -- Answer ✔✔ 10 IU a day OR
0.1-0.2 IU/kg a day and then titrated up from there based on fasting glucose
results


- Add basal analog or bedtime NPH insulin
• initiation: start 10 units per day or 0.1-0.2 IU/kg a day
• set FPG target
• choose evidence-based titration algorithm: example: increase 2 units every
3 days to reach FPG target without hypoglycemia
• for hypoglycemia determine the cause, if no clear reason lower dose by
10-20%


3) anti-diabetic drugs more or less likely to cause hypoglycemia:

, - thiazolidnediones
- insulin
- sulfonylureas
- incretin mimetics
- metformin
- dpp-4 inhibitors
- meglitinides
- amylin analogues -- Answer ✔✔ More Likely To Cause Hypoglycemia
insulin
sulfonylureas
meglitinides
amylin analogues


Less Likely To Cause Hypoglycemia
incretin mimetics
metformin
thiazolidnediones
dpp-4 inhibitors


4) Match the correct drug class with the agent(s): Biguanides


- sitagliptin (Januvia)
- Saxagliptin(onglyza)
- Linagliptin (Tradjenta)
- Alogliptin(Nesina)
- canagliflozin (Invokana)
- dapagliflozin (Farxiga)
- empagliflozin (Jardiance)
- Glyburide
- Glipizide
- Glimepiride
- Metformin
- Rosiglitzaone(Avandia)
- Pioglitazone (Actos)
- Dulaglutide (Trulicity)
- Semaglutide(Ozempic)

, - Liraglutide (Victoza) -- Answer ✔✔ Metformin


5) Match the correct drug class with the agent(s): Glucagon-Like Peptide 1 Receptor
Agonists (GLP-1 )


- sitagliptin (Januvia)
- Saxagliptin(onglyza)
- Linagliptin (Tradjenta)
- Alogliptin(Nesina)
- canagliflozin (Invokana)
- dapagliflozin (Farxiga)
- empagliflozin (Jardiance)
- Glyburide
- Glipizide
- Glimepiride
- Metformin
- Rosiglitzaone(Avandia)
- Pioglitazone (Actos)
- Dulaglutide (Trulicity)
- Semaglutide(Ozempic)
- Liraglutide (Victoza) -- Answer ✔✔ Dulaglutide (Trulicity)
- Semaglutide(Ozempic)
- Liraglutide (Victoza)


6) Match the correct drug class with the agent(s): Sodium-glucose co-transporter 2
inhibitors (SGLT2-I)


- sitagliptin (Januvia)
- Saxagliptin(onglyza)
- Linagliptin (Tradjenta)
- Alogliptin(Nesina)
- canagliflozin (Invokana)
- dapagliflozin (Farxiga)
- empagliflozin (Jardiance)
- Glyburide

, - Glipizide
- Glimepiride
- Metformin
- Rosiglitzaone(Avandia)
- Pioglitazone (Actos)
- Dulaglutide (Trulicity)
- Semaglutide(Ozempic)
- Liraglutide (Victoza) -- Answer ✔✔ canagliflozin (Invokana)
dapagliflozin (Farxiga)
empagliflozin (Jardiance)


7) Match the correct drug class with the agent(s): Dipeptidyl peptidase-4 (DPP-4i)


- sitagliptin (Januvia)
- Saxagliptin(onglyza)
- Linagliptin (Tradjenta)
- Alogliptin(Nesina)
- canagliflozin (Invokana)
- dapagliflozin (Farxiga)
- empagliflozin (Jardiance)
- Glyburide
- Glipizide
- Glimepiride
- Metformin
- Rosiglitzaone(Avandia)
- Pioglitazone (Actos)
- Dulaglutide (Trulicity)
- Semaglutide(Ozempic)
- Liraglutide (Victoza) -- Answer ✔✔ sitagliptin (Januvia)
Saxagliptin(onglyza)
Linagliptin (Tradjenta)
Alogliptin(Nesina)


8) Match the correct drug class with the agent(s): Thiazolidinediones (TZD)


- sitagliptin (Januvia)