LEHNINGER PRINCIPLES OF BIOCHEMISTRY 5
EXAMINATION TEST PAPER 2026
COMPREHENSIVE REVIEW SOLVED
QUESTIONS ANSWERS GRADED A+
◉ cofactor.
Answer: An inorganic ion or a coenzyme required for enzyme
activity.
◉ coenzyme.
Answer: An organic cofactor required for the action of certain
enzymes; often has a vitamin component.
◉ prosthetic group.
Answer: A metal ion or organic compound (other than an amino
acid) covalently bound to a protein and essential in its activity.
◉ holoenzyme.
Answer: A catalytically active enzyme, including all necessary
subunits, prosthetic groups, and cofactors.
◉ apoenzyme.
, Answer: The protein portion of an enzyme, exclusive of any organic
or inorganic cofactors or prosthetic groups that might be required
for catalytic activity.
◉ apoprotein.
Answer: The protein portion of a protein, exclusive of any organic or
inorganic cofactors or prosthetic groups that might be required for
activity.
◉ active site.
Answer: The region of an enzyme surface that binds the substrate
molecule and catalytically transforms it; also known as the catalytic
site.
◉ substrate.
Answer: The specific compound acted upon by an enzyme.
◉ ground state.
Answer: The normal, stable form of an atom or molecule, as distinct
from the excited state.
◉ transition state.
EXAMINATION TEST PAPER 2026
COMPREHENSIVE REVIEW SOLVED
QUESTIONS ANSWERS GRADED A+
◉ cofactor.
Answer: An inorganic ion or a coenzyme required for enzyme
activity.
◉ coenzyme.
Answer: An organic cofactor required for the action of certain
enzymes; often has a vitamin component.
◉ prosthetic group.
Answer: A metal ion or organic compound (other than an amino
acid) covalently bound to a protein and essential in its activity.
◉ holoenzyme.
Answer: A catalytically active enzyme, including all necessary
subunits, prosthetic groups, and cofactors.
◉ apoenzyme.
, Answer: The protein portion of an enzyme, exclusive of any organic
or inorganic cofactors or prosthetic groups that might be required
for catalytic activity.
◉ apoprotein.
Answer: The protein portion of a protein, exclusive of any organic or
inorganic cofactors or prosthetic groups that might be required for
activity.
◉ active site.
Answer: The region of an enzyme surface that binds the substrate
molecule and catalytically transforms it; also known as the catalytic
site.
◉ substrate.
Answer: The specific compound acted upon by an enzyme.
◉ ground state.
Answer: The normal, stable form of an atom or molecule, as distinct
from the excited state.
◉ transition state.
