NURS 663: EXAM 1 STUDY GUIDE QUESTIONS WITH 100%
CORRECT ANSWERS
1) What medications can cause SIADH? -- Answer ✔✔ - carbamazepine
- Ssris
- Amitriptyline
- Morphine
2) How is SIADH reflected in lab values? -- Answer ✔✔ decreased serum
osmolality (increased serum volume)
Increased urine osmolality (decreased urine volume)
3) What two medications are most likely to cause discontinuation syndrome? --
Answer ✔✔ paroxetine (paxil) and venlafaxine (effexor)
4) Which ssris have no sexual side effects -- Answer ✔✔ mirtazapine, nefazadone,
buproprion
5) Which antidepressants are more activating? -- Answer ✔✔ bupropion,
venlafaxine, fluoxetine
,6) Which antidepressants are more sedating? -- Answer ✔✔ trazodone, tcas,
paroxetine, mirtazapine
7) Which antidepressants are more associated with weight gain? -- Answer ✔✔
Mirtazapine
Paroxetine
TCA's
8) Which antidepressants might be associated with weight loss? -- Answer ✔✔
bupropion
9) What antidepressant is useful for nicotine cessation? -- Answer ✔✔ bupropion
10) What antidepressant might help with methamphetamine withdrawal? -- Answer
✔✔ mirtazapine
11) What antidepressants might be useful with ADHD? -- Answer ✔✔ bupropion,
venlafaxine
12) Which antidepressants might be useful with pain disorders? -- Answer ✔✔
•Duloxetine
• Venlafaxine
Amitriptyline
13) Which antidepressant might be useful with headaches? -- Answer ✔✔
amitriptyline
14) Which preexisting condition should be avoided in the prescription of bupropion?
-- Answer ✔✔ seizure disorder
, 15) How does paroxetine interact at the 2d6 site? -- Answer ✔✔ it is a potent
inhibitor and substrate (tons of medication interactions)
16) How could the long half life of fluoxetine been of benefit and risk? -- Answer ✔✔
benefit: decrease withdrawal/discontinuation symptoms
Negative: if patient has side effects, long time to get out of system
17) What are the biggest risks in tcas? -- Answer ✔✔ cardiotoxic
Very dangerous in overdose (NO SUICIDAL PATIENTS!)
18) What are maois minimally prescribed? -- Answer ✔✔ lots of food interactions
(tyramine)
Require 2-6 weeks to build up in system d/t long period between RX and other
medications
Dangerous in overdose
19) All antidepressants carry what 5 warnings? -- Answer ✔✔ - increased risk of
suicide (especially in children and young adults)
- Mania activation
- Serotonin syndrome
- discontinuation syndrome
- Bleeding risk
20) What antidepressants are more activating? -- Answer ✔✔ Wellbutrin, Prozac,
Effexor, Pristiq, Viibryd
CORRECT ANSWERS
1) What medications can cause SIADH? -- Answer ✔✔ - carbamazepine
- Ssris
- Amitriptyline
- Morphine
2) How is SIADH reflected in lab values? -- Answer ✔✔ decreased serum
osmolality (increased serum volume)
Increased urine osmolality (decreased urine volume)
3) What two medications are most likely to cause discontinuation syndrome? --
Answer ✔✔ paroxetine (paxil) and venlafaxine (effexor)
4) Which ssris have no sexual side effects -- Answer ✔✔ mirtazapine, nefazadone,
buproprion
5) Which antidepressants are more activating? -- Answer ✔✔ bupropion,
venlafaxine, fluoxetine
,6) Which antidepressants are more sedating? -- Answer ✔✔ trazodone, tcas,
paroxetine, mirtazapine
7) Which antidepressants are more associated with weight gain? -- Answer ✔✔
Mirtazapine
Paroxetine
TCA's
8) Which antidepressants might be associated with weight loss? -- Answer ✔✔
bupropion
9) What antidepressant is useful for nicotine cessation? -- Answer ✔✔ bupropion
10) What antidepressant might help with methamphetamine withdrawal? -- Answer
✔✔ mirtazapine
11) What antidepressants might be useful with ADHD? -- Answer ✔✔ bupropion,
venlafaxine
12) Which antidepressants might be useful with pain disorders? -- Answer ✔✔
•Duloxetine
• Venlafaxine
Amitriptyline
13) Which antidepressant might be useful with headaches? -- Answer ✔✔
amitriptyline
14) Which preexisting condition should be avoided in the prescription of bupropion?
-- Answer ✔✔ seizure disorder
, 15) How does paroxetine interact at the 2d6 site? -- Answer ✔✔ it is a potent
inhibitor and substrate (tons of medication interactions)
16) How could the long half life of fluoxetine been of benefit and risk? -- Answer ✔✔
benefit: decrease withdrawal/discontinuation symptoms
Negative: if patient has side effects, long time to get out of system
17) What are the biggest risks in tcas? -- Answer ✔✔ cardiotoxic
Very dangerous in overdose (NO SUICIDAL PATIENTS!)
18) What are maois minimally prescribed? -- Answer ✔✔ lots of food interactions
(tyramine)
Require 2-6 weeks to build up in system d/t long period between RX and other
medications
Dangerous in overdose
19) All antidepressants carry what 5 warnings? -- Answer ✔✔ - increased risk of
suicide (especially in children and young adults)
- Mania activation
- Serotonin syndrome
- discontinuation syndrome
- Bleeding risk
20) What antidepressants are more activating? -- Answer ✔✔ Wellbutrin, Prozac,
Effexor, Pristiq, Viibryd
