NSG 530 Exam 1 (Latest )
Advanced Pathophysiology Questions and
Verified Answers 100% Correct (Grade A)-
Wilkes
There is a disease of the spleen, which results in an excessive destruction of RBCs.
This increase in RBC destruction can lead to which of the following?
a. hypoxia
b. hypobilirubinemia
c. an increase in platelets
d. all of the above - correct answer A
Your body has developed an increased demand for thyroid hormones. This will lead to
____________ of the thyroid gland.
a. atrophy
b. hypertrophy
c. dysplasia
d. metaplasia - correct answer B
,You palpate a gangrenous leg and note the presence of crepitus. Crepitus is associated
with which of the following?
a. wet gangrene
b. dry gangrene
c. gas gangrene
d. all of the above - correct answer C
Direct cell membrane destruction may result from which of the following?
a. complement activation
b. bacterial enzymes
c. free radicals
d. all of the above - correct answer D
Which of the following is true regarding apoptosis?
a. It occurrence may be physiological or pathological.
b. It does not stimulate the inflammatory process.
c. It results in phagocytosis of the apoptotic cell.
d. all of the above. - correct answer D
,Insufficient blood flow to a part of the body is defined as:
a. hypoxia.
b. hypoxemia.
c. necrosis.
d. ischemia. - correct answer D
A cellular change, which is often precancerous, is called:
a. hyperplasia.
b. metaplasia.
c. dysplasia.
d. hypertrophy. - correct answer C
Which of the following changes is indicative of irreversible cell injury?
a. sodium influx into the cytoplasm
b. glycolysis (anaerobic metabolism)
c. detachment of ribosomes from rough endoplasmic reticulum
d. release of lysosomal enzymes - correct answer D
, Metaplasia - correct answer reversible replacement of one mature cell type (epithelial
or mesenchymal) by another, sometimes less differentiated, cell type.
Cause of metaplasia - correct answer develops from reprogramming of stem cells.
Found in association with tissue damage, repair, and regeneration.
pathophysiology of metaplasia - correct answer Adaptive replacement cell may be
more suitable to the changed conditions in the surrounding environment. Ex. GERD
damages squamous epithelium of the esophagus, cells are replaced by glandular
epithelium which may tolerate the acid better. Not always beneficial. Ex. Smoking
causes changes in bronchi cells, which don't have cilia or secrete mucus, causing loss
of protective mechanism.
What is the significance of metaplasia - correct answer Can be reversed if stimulus is
removed. If continues, can cause malignant transformation.
Advanced Pathophysiology Questions and
Verified Answers 100% Correct (Grade A)-
Wilkes
There is a disease of the spleen, which results in an excessive destruction of RBCs.
This increase in RBC destruction can lead to which of the following?
a. hypoxia
b. hypobilirubinemia
c. an increase in platelets
d. all of the above - correct answer A
Your body has developed an increased demand for thyroid hormones. This will lead to
____________ of the thyroid gland.
a. atrophy
b. hypertrophy
c. dysplasia
d. metaplasia - correct answer B
,You palpate a gangrenous leg and note the presence of crepitus. Crepitus is associated
with which of the following?
a. wet gangrene
b. dry gangrene
c. gas gangrene
d. all of the above - correct answer C
Direct cell membrane destruction may result from which of the following?
a. complement activation
b. bacterial enzymes
c. free radicals
d. all of the above - correct answer D
Which of the following is true regarding apoptosis?
a. It occurrence may be physiological or pathological.
b. It does not stimulate the inflammatory process.
c. It results in phagocytosis of the apoptotic cell.
d. all of the above. - correct answer D
,Insufficient blood flow to a part of the body is defined as:
a. hypoxia.
b. hypoxemia.
c. necrosis.
d. ischemia. - correct answer D
A cellular change, which is often precancerous, is called:
a. hyperplasia.
b. metaplasia.
c. dysplasia.
d. hypertrophy. - correct answer C
Which of the following changes is indicative of irreversible cell injury?
a. sodium influx into the cytoplasm
b. glycolysis (anaerobic metabolism)
c. detachment of ribosomes from rough endoplasmic reticulum
d. release of lysosomal enzymes - correct answer D
, Metaplasia - correct answer reversible replacement of one mature cell type (epithelial
or mesenchymal) by another, sometimes less differentiated, cell type.
Cause of metaplasia - correct answer develops from reprogramming of stem cells.
Found in association with tissue damage, repair, and regeneration.
pathophysiology of metaplasia - correct answer Adaptive replacement cell may be
more suitable to the changed conditions in the surrounding environment. Ex. GERD
damages squamous epithelium of the esophagus, cells are replaced by glandular
epithelium which may tolerate the acid better. Not always beneficial. Ex. Smoking
causes changes in bronchi cells, which don't have cilia or secrete mucus, causing loss
of protective mechanism.
What is the significance of metaplasia - correct answer Can be reversed if stimulus is
removed. If continues, can cause malignant transformation.
