PHCY 514 EXAM 2 QUESTIONS WITH
100% CORRECT ANSWERS
\.Which is NOT a use of recombinant DNA technology:
A. Creation of human protein therapies
B. Creation of unique therapeutic fusion proteins
C. Creation of unique diagnostic fusion proteins
D. Creation of small molecules to produce therapies - ANSWERS-d
\.TRAIL is a potent anticancer protein. Creation of a TRAIL-based protein therapy
begins with isolating the _____________?
A. DNA cloning and assembly
B. Cell culture
C. Protein isolation
D. Cancer cells sensitive to TRAIL - ANSWERS-a
\._______________ are small "protein factories" that produce therapeutic
proteins before they are isolated and lyopholized.
A. Transfection reagents
B. DNA plasmids
C. Chemical reactions
D. Cells - ANSWERS-d
, \.Which of the following is correct:
A. A biosimilar has identical clinical properties to the original biologic.
B. Biologics are complex molecules produced using biological systems.
C. Biologics can include chemically synthesized small molecules
D. A biosimilar has identical physicochemical properties to the original biologic. -
ANSWERS-b
\.Which is NOT an example of biologics?
A. Cytokine
B. Monoclonal antibodies
C. Adeno-associated viral gene vectors
D. Aspirin - ANSWERS-d
\.Protein drugs are comprised of:
A. Chains of amino acids
B. Chemically linked small molecule compounds
C. DNA and RNA
D. Cells of the immune system - ANSWERS-a
\.Which statement is true regarding small molecule drugs and protein drugs?
A. Protein therapies have more established guidelines for manufacturing and
testing than small molecule drugs
B. Protein therapies are more stable than small molecule drugs
100% CORRECT ANSWERS
\.Which is NOT a use of recombinant DNA technology:
A. Creation of human protein therapies
B. Creation of unique therapeutic fusion proteins
C. Creation of unique diagnostic fusion proteins
D. Creation of small molecules to produce therapies - ANSWERS-d
\.TRAIL is a potent anticancer protein. Creation of a TRAIL-based protein therapy
begins with isolating the _____________?
A. DNA cloning and assembly
B. Cell culture
C. Protein isolation
D. Cancer cells sensitive to TRAIL - ANSWERS-a
\._______________ are small "protein factories" that produce therapeutic
proteins before they are isolated and lyopholized.
A. Transfection reagents
B. DNA plasmids
C. Chemical reactions
D. Cells - ANSWERS-d
, \.Which of the following is correct:
A. A biosimilar has identical clinical properties to the original biologic.
B. Biologics are complex molecules produced using biological systems.
C. Biologics can include chemically synthesized small molecules
D. A biosimilar has identical physicochemical properties to the original biologic. -
ANSWERS-b
\.Which is NOT an example of biologics?
A. Cytokine
B. Monoclonal antibodies
C. Adeno-associated viral gene vectors
D. Aspirin - ANSWERS-d
\.Protein drugs are comprised of:
A. Chains of amino acids
B. Chemically linked small molecule compounds
C. DNA and RNA
D. Cells of the immune system - ANSWERS-a
\.Which statement is true regarding small molecule drugs and protein drugs?
A. Protein therapies have more established guidelines for manufacturing and
testing than small molecule drugs
B. Protein therapies are more stable than small molecule drugs
