NURS 6521 Exam 1 (Latest
Update) Advanced Pharmacology
Questions with Verified Answers 100%
Correct {Graded A} - Walden.
While rational drug selection is based on the individual patient the aspect of rational
drug selection addressing disease-specific information by a national medical or
nursing organization is
A. a guideline
B. cost
C. availability
D. patient hepatic and renal function - correct answer A. A guideline
One aspect of promotion of positive outcomes is medication education. Identify the
incorrect statement. (Ch. 3)
A. Teach the patient purpose of the drug.
B. Teach the patient where to purchase the drug.
,C. Teach the patient the dosing schedule.
D. Teach the patient about adverse reactions. - correct answer B. Teach the pt where
to purchase the drug
A medication is a weak base that ionizes at a pH of 4 and lower. The medication is
administered orally. Which of the following statements is accurate?
A. It will be absorbed primarily in the stomach and become ionized once it reaches the
small intestine.
B. it will be absorbed primarily in the small intestine and become ionized once it
reaches the blood stream.
C. Whenever it becomes ionized, the drug will attach to an active transport receptor
and be carried into the blood stream.
D. It will be absorbed in the small intestine and be non-ionized in the blood stream and
will be able to enter into a lactating woman's breast milk and also return to the
bloodstream from the breast milk. - correct answer D
,It is a weak base so, in this case it is a non-ionized in any pH greater than 4 - so it will
be absorbed in small intestines, stay ionized in blood (7.45-7.45) and also be able to
enter breast milk; since breast milk is 7.1, it will not ionize there either; there are not
transport receptors for just any drug and they would not be active transport bc it is not
an up gradient situation.
Referring to the same drug above (weak base that ionizes at <4). What will happen to
its absorbability if the person takes omeprazole which raises the gastric pH to 5?
A. The drug will only be absorbed in the small intestine because it is a weak base.
B. The drug will be absorbed in the stomach and the small intestines.
C. The drug will ionize in both stomach and small intestine thus increasing its total
absorption.
D. The drug will become a weak acid. - correct answer B
The only that changes is that it is not ionized in the stomach so it can also be absorbed
there as well as any other area with a pH of 4.
, A blood pressure drug is small, lipid soluble with no charge at all times and is 99%
protein bound. The patient's dose has been titrated and is at the appropriate dose
maintain good control of his HTN. Recently, the patient begins to take daily high doses
of an additional OTC drug that is also small, lipid soluble, carries no charge and is
highly protein bound. Which of the following is likely to happen with the introduction of
the second drug?
A. The absorption of the blood pressure drug will increase because it is small, lipid
soluble and has no charge
B. The blood pressure drug will have decreased effectiveness.
C. The patient will need to be monitored as he may become hypotensive.
D. Since both drugs are small, lipid soluble and have no charge, the will compete with
eachother at the same receptor sites on body tissues. - correct answer C
If 1 protein-bound drug's dose is titrated for a specific effect, when you add another
highly protein bound drug, both of them will compete for receptor sites on the albumin
and more free (think active) drug will be in the plasma - this puts the person at risk for
Update) Advanced Pharmacology
Questions with Verified Answers 100%
Correct {Graded A} - Walden.
While rational drug selection is based on the individual patient the aspect of rational
drug selection addressing disease-specific information by a national medical or
nursing organization is
A. a guideline
B. cost
C. availability
D. patient hepatic and renal function - correct answer A. A guideline
One aspect of promotion of positive outcomes is medication education. Identify the
incorrect statement. (Ch. 3)
A. Teach the patient purpose of the drug.
B. Teach the patient where to purchase the drug.
,C. Teach the patient the dosing schedule.
D. Teach the patient about adverse reactions. - correct answer B. Teach the pt where
to purchase the drug
A medication is a weak base that ionizes at a pH of 4 and lower. The medication is
administered orally. Which of the following statements is accurate?
A. It will be absorbed primarily in the stomach and become ionized once it reaches the
small intestine.
B. it will be absorbed primarily in the small intestine and become ionized once it
reaches the blood stream.
C. Whenever it becomes ionized, the drug will attach to an active transport receptor
and be carried into the blood stream.
D. It will be absorbed in the small intestine and be non-ionized in the blood stream and
will be able to enter into a lactating woman's breast milk and also return to the
bloodstream from the breast milk. - correct answer D
,It is a weak base so, in this case it is a non-ionized in any pH greater than 4 - so it will
be absorbed in small intestines, stay ionized in blood (7.45-7.45) and also be able to
enter breast milk; since breast milk is 7.1, it will not ionize there either; there are not
transport receptors for just any drug and they would not be active transport bc it is not
an up gradient situation.
Referring to the same drug above (weak base that ionizes at <4). What will happen to
its absorbability if the person takes omeprazole which raises the gastric pH to 5?
A. The drug will only be absorbed in the small intestine because it is a weak base.
B. The drug will be absorbed in the stomach and the small intestines.
C. The drug will ionize in both stomach and small intestine thus increasing its total
absorption.
D. The drug will become a weak acid. - correct answer B
The only that changes is that it is not ionized in the stomach so it can also be absorbed
there as well as any other area with a pH of 4.
, A blood pressure drug is small, lipid soluble with no charge at all times and is 99%
protein bound. The patient's dose has been titrated and is at the appropriate dose
maintain good control of his HTN. Recently, the patient begins to take daily high doses
of an additional OTC drug that is also small, lipid soluble, carries no charge and is
highly protein bound. Which of the following is likely to happen with the introduction of
the second drug?
A. The absorption of the blood pressure drug will increase because it is small, lipid
soluble and has no charge
B. The blood pressure drug will have decreased effectiveness.
C. The patient will need to be monitored as he may become hypotensive.
D. Since both drugs are small, lipid soluble and have no charge, the will compete with
eachother at the same receptor sites on body tissues. - correct answer C
If 1 protein-bound drug's dose is titrated for a specific effect, when you add another
highly protein bound drug, both of them will compete for receptor sites on the albumin
and more free (think active) drug will be in the plasma - this puts the person at risk for
