PSYC 3650 EXAM 3 STUDY GUIDE
mechanism of action for cocaine - Answers - blocks reuptake of dopamine in the
presynaptic membrane
mechanism of action for amphetamines - Answers - promotes release and blocks
reuptake of dopamine
Baseline level of impulsivity - Answers - predicts if a subject will self-administer drugs
Opioid deprivation in opiate addicts - Answers - causes higher impulsivity
Kappa agonists - Answers - related to withdrawal
Mu agonists - Answers - associated with reinforcement
Substance P - Answers - increases pain
Endorphins - Answers - decreases pain
Low doses of opioids - Answers - increase locomotor activity
High doses of opioids - Answers - decrease locomotor activity
Extremely high doses of opioids - Answers - cause catalepsy
Mu receptor agonism - Answers - analgesia, euphoria, constipation, and respiratory
depression
Epinephrine - Answers - deemed inefficient as a treatment taken orally
Opioid treatments - Answers - Methadone
Opioid treatments - Answers - Buprenorphine
Opioid treatments - Answers - Naltrexone
Major social development in the 60s - Answers - Crackdown caused shortage of heroin
and increased smuggling & price
Major social development in the 60s - Answers - Drug culture
Major social development in the 60s - Answers - Vietnam war
, Opium - Answers - doesn't cross the blood-brain barrier
Heroin - Answers - does cross the blood-brain barrier
Heroin - Answers - metabolized into morphine
Chronic effects of smoking - Answers - lower levels of psychological well-being
acute effects of smoking - Answers - rush, buzz, or high, subjective effects similar to
morphine and amphetamine
nicotinic distribution - Answers - passes the blood-brain barrier, placenta, even in breast
milk
nicotine - Answers - acetylcholine agonist
CNS effects of nicotine - Answers - causes increased respiration, arousal, effects the
vomiting center and causes release of dopamine
PNS effects of nicotine - Answers - increased heart rate and blood pressure,
constriction of blood vessels, inhibits stomach secretions, stimulates the bowel
nicotine elimination - Answers - 30-40% in the kidneys in first order kinetics, 90%
metabolized in the liver
highest level of nicotine - Answers - inhalation
second highest level of nicotine - Answers - intranasal administration
third highest level of nicotine - Answers - transdermal administration
lowest level of nicotine - Answers - oral administration
Odum, Madden, Bickel (2002) - Answers - Current smokers discounted delayed health
gains and health losses more steeply than never-smokers did.
Discounting by ex-smokers was generally intermediate to that of current smokers and
never-smokers, although not statistically different from either. Current smokers and ex-
smokers discounted delayed health losses more steeply than they did health gains.
Never-smokers did not discount gains and losses differently.
Cigarette smokers show rapid loss of value for delayed health outcomes, emphasizing
the need for smoking-cessation treatments that provide relatively immediate
consequences for abstinence
highest peak concentration of cocaine - Answers - i.v.
mechanism of action for cocaine - Answers - blocks reuptake of dopamine in the
presynaptic membrane
mechanism of action for amphetamines - Answers - promotes release and blocks
reuptake of dopamine
Baseline level of impulsivity - Answers - predicts if a subject will self-administer drugs
Opioid deprivation in opiate addicts - Answers - causes higher impulsivity
Kappa agonists - Answers - related to withdrawal
Mu agonists - Answers - associated with reinforcement
Substance P - Answers - increases pain
Endorphins - Answers - decreases pain
Low doses of opioids - Answers - increase locomotor activity
High doses of opioids - Answers - decrease locomotor activity
Extremely high doses of opioids - Answers - cause catalepsy
Mu receptor agonism - Answers - analgesia, euphoria, constipation, and respiratory
depression
Epinephrine - Answers - deemed inefficient as a treatment taken orally
Opioid treatments - Answers - Methadone
Opioid treatments - Answers - Buprenorphine
Opioid treatments - Answers - Naltrexone
Major social development in the 60s - Answers - Crackdown caused shortage of heroin
and increased smuggling & price
Major social development in the 60s - Answers - Drug culture
Major social development in the 60s - Answers - Vietnam war
, Opium - Answers - doesn't cross the blood-brain barrier
Heroin - Answers - does cross the blood-brain barrier
Heroin - Answers - metabolized into morphine
Chronic effects of smoking - Answers - lower levels of psychological well-being
acute effects of smoking - Answers - rush, buzz, or high, subjective effects similar to
morphine and amphetamine
nicotinic distribution - Answers - passes the blood-brain barrier, placenta, even in breast
milk
nicotine - Answers - acetylcholine agonist
CNS effects of nicotine - Answers - causes increased respiration, arousal, effects the
vomiting center and causes release of dopamine
PNS effects of nicotine - Answers - increased heart rate and blood pressure,
constriction of blood vessels, inhibits stomach secretions, stimulates the bowel
nicotine elimination - Answers - 30-40% in the kidneys in first order kinetics, 90%
metabolized in the liver
highest level of nicotine - Answers - inhalation
second highest level of nicotine - Answers - intranasal administration
third highest level of nicotine - Answers - transdermal administration
lowest level of nicotine - Answers - oral administration
Odum, Madden, Bickel (2002) - Answers - Current smokers discounted delayed health
gains and health losses more steeply than never-smokers did.
Discounting by ex-smokers was generally intermediate to that of current smokers and
never-smokers, although not statistically different from either. Current smokers and ex-
smokers discounted delayed health losses more steeply than they did health gains.
Never-smokers did not discount gains and losses differently.
Cigarette smokers show rapid loss of value for delayed health outcomes, emphasizing
the need for smoking-cessation treatments that provide relatively immediate
consequences for abstinence
highest peak concentration of cocaine - Answers - i.v.
