Antipsychotics, Antiepileptics, Antidepressants | Q&A | Grade A | 100%
Correct (Verified Answers)
COMPREHENSIVE PHARMACOLOGY REVIEW | LATEST 2026/2027
SUBJECT SOURCE FORMAT
Pharmacology NUR 210 Exam 1 2026/2027 Q&A with Clinical Rationale
1
Non-benzodiazepine used for insomnia
CORRECT ANSWER: Zolpidem (Ambien)
CLINICAL RATIONALE
1. Zolpidem is a non-benzodiazepine hypnotic (Z-drug) that binds to GABA-A receptors.
2. Schedule IV controlled substance; use with caution in older adults due to fall risk.
2
Benzodiazepine used for status epilepticus
CORRECT ANSWER: Diazepam (Valium)
CLINICAL RATIONALE
1. Diazepam is preferred for status epilepticus due to rapid onset and long duration.
2. Administered IV; may also be given rectally for out-of-hospital use.
3
Benzodiazepine used for anxiety
CORRECT ANSWER: Lorazepam (Ativan)
CLINICAL RATIONALE
1. Lorazepam is intermediate-acting, preferred for anxiety due to reliable absorption.
2. Also used for alcohol withdrawal and pre-procedural sedation.
4
What type of receptor do benzodiazepines target?
CORRECT ANSWER: GABA receptors (GABA-A)
CLINICAL RATIONALE
1. Benzodiazepines potentiate GABA's inhibitory effects by increasing chloride channel opening frequency.
, 5
All CNS depressants can adversely affect which two vital signs?
CORRECT ANSWER: Blood pressure and respiratory rate
CLINICAL RATIONALE
1. CNS depressants cause hypotension, bradycardia, and respiratory depression.
6
Which CNS depressant medication can cause vivid dreams and nightmares?
CORRECT ANSWER: Zolpidem
CLINICAL RATIONALE
1. Zolpidem can cause sleep-related behaviors (sleepwalking, sleep-eating) and vivid dreams.
7
Major side effect for local lidocaine administration?
CORRECT ANSWER: Prolonged loss of sensation
CLINICAL RATIONALE
1. Overdose can cause CNS toxicity (seizures) and cardiac toxicity (arrhythmias).
8
What class of drug is used for substance abuse withdrawal?
CORRECT ANSWER: Benzodiazepines
CLINICAL RATIONALE
1. Benzodiazepines prevent seizures and manage withdrawal symptoms in alcohol and sedative-hypnotic withdrawal.
9
Non-selective NSAID used to prevent inflammation, fever, and pain?
CORRECT ANSWER: Ibuprofen (Motrin, Advil)
CLINICAL RATIONALE
1. Non-selective NSAIDs inhibit both COX-1 and COX-2, reducing prostaglandin synthesis.