PHARM HESI V1, V2, V3 2026-2027 MOST RECENT VERSION
QUESTIONS AND VERIFIED ANSWERS ACCURATE SOLUTIONS
ALREADY GRADED A+| NEW UPDATE!!!!!!!!!!!!!!!!!!!!!!!
Drugs classified in the Category X place a client who is in the first trimester of
pregnancy at risk for teratogenesis, so women in the childbearing years should be
counseled to use a reliable form of birth control during drug therapy. If the client is
planning to become pregnant, she should be encouraged to discuss plans for
pregnancy with the healthcare provider, so a safer alternative prescription can be
provided if pregnancy occurs.
A client being discharged home is prescribed an antibiotic with a dosage three
times higher than it was administered when the client was in the hospital. Which
route of administration should the nurse anticipate will be prescribed for the
greatest first-pass effect?
A. Oral.
B. Sublingual.
C. Intravenous.
D. Subcutaneous. - ANS... -A. Oral.
The first-pass effect is a pharmacokinetic phenomenon that is related to the drug's
metabolism in the liver. After oral medications are absorbed from the
gastrointestinal tract, the drug is carried directly to the liver via the hepatic portal
circulation, where hepatic inactivation occurs and reduces the bioavailability
(strength/concentration) of the drug.
The healthcare provider prescribes naproxen (Naproxen) twice daily for a client
with osteoarthritis of the hands. The client tells the nurse that the drug does not
seem to be effective after three weeks. Which is the best response for the nurse to
provide?
A. The frequency of the dosing is necessary to increase the effectiveness.
B. Therapeutic blood levels of this drug are reached in 4 to 6 weeks.
C. Another type of nonsteroidal antiinflammatory drug may be indicated.
D. Systemic corticosteroids are the next drugs of choice for pain relief. - ANS... -
C. Another type of nonsteroidal antiinflammatory drug may be indicated.
,Individual responses to nonsteroidal antiinflammatory drugs are vary from person
to person, so another nonsteroidal antiinflammatory drug (NSAID) may be
indicated for this particular client.
After abdominal surgery, a client is prescribed low molecular weight heparin
(LMWH). During administration of the medication, the client asks the nurse the
reason for the medication. Which is the best response for the nurse to provide the
client?
A. This medication is given to prevent blood clot formation.
B. This medication enhances antibiotics to prevent infection.
C. This medication dissolves clots that develop in the legs.
D. This medication enhances the healing of wounds. - ANS... -A. This medication
is given to prevent blood clot formation.
A 43-year-old female client is prescribed thyroid replacement hormone following a
thyroidectomy. Which adverse effects should the nurse instruct the client to report
immediately to the healthcare provider?
A. Tinnitus and dizziness.
B. Tachycardia and chest pain.
C. Dry skin and intolerance to cold.
D. Weight gain and increased appetite. - ANS... -B. Tachycardia and chest pain.
Thyroid replacement hormone increases the metabolic rate of all tissues. Common
signs and symptoms of toxicity include tachycardia and chest pain and should be
reported to the healthcare provider immediately.
A client prescribed albuterol tablets reports nausea every evening with the 9:00
p.m. dose. Which action should the nurse perform to alleviate this side effect?
A. Change the time of the dose.
B. Hold the 9 p.m. dose.
C. Administer the dose with a snack.
D. Offer an antiemetic with the dose. - ANS... -C. Administer the dose with a
snack.
Administering oral doses of albuterol with food helps minimize gastrointestinal
discomfort such as nausea.
, A client is prescribed ampicillin sodium (Omnipen) for a sinus infection. The nurse
should instruct the client to notify the healthcare provider immediately if which
symptom occurs?
A. Rash.
B. Nausea.
C. Headache.
D. Dizziness - ANS... -A. Rash.
Rash is the most common adverse effect of all penicillins, indicating an allergy to
the medication that could result in anaphylactic shock, a medical emergency.
A peak and trough level is prescribed for a client receiving antibiotic therapy.
When should the nurse should obtain the trough level?
A. Sixty minutes after the antibiotic dose is administered.
B. Immediately before the next antibiotic dose is given.
C. Upon completion of the prescribed antibiotic regime.
D. An hour before the next antibiotic dose is given. - ANS... -B. Immediately
before the next antibiotic dose is given.
Trough levels are drawn when the blood level is at its lowest, which is typically
just before the next dose is given.
The nurse is caring for a client who has taken atenolol for 2 years. The healthcare
provider recently changed the medication to enalapril to manage the client's blood
pressure. Which instruction should the nurse provide the client regarding the new
medication?
A. Take the medication at bedtime.
B. Report presence of increased bruising.
C. Check pulse before taking medication.
D. Rise slowly when getting out of bed or chair. - ANS... -D. Rise slowly when
getting out of bed or chair.
The client's new medication is an angiotensin-converting enzyme (ACE) inhibitor,
which has the side effect oforthostatic hypotension. Instructing the client to rise
slowly from a sitting or lying down position is important to teach the client to
avoid dizziness and potentially falling.
A female client calls the clinic and talks with the nurse to inquire about a possible
reaction after taking amoxicillin for 5 days. She reports having vaginal discomfort,
QUESTIONS AND VERIFIED ANSWERS ACCURATE SOLUTIONS
ALREADY GRADED A+| NEW UPDATE!!!!!!!!!!!!!!!!!!!!!!!
Drugs classified in the Category X place a client who is in the first trimester of
pregnancy at risk for teratogenesis, so women in the childbearing years should be
counseled to use a reliable form of birth control during drug therapy. If the client is
planning to become pregnant, she should be encouraged to discuss plans for
pregnancy with the healthcare provider, so a safer alternative prescription can be
provided if pregnancy occurs.
A client being discharged home is prescribed an antibiotic with a dosage three
times higher than it was administered when the client was in the hospital. Which
route of administration should the nurse anticipate will be prescribed for the
greatest first-pass effect?
A. Oral.
B. Sublingual.
C. Intravenous.
D. Subcutaneous. - ANS... -A. Oral.
The first-pass effect is a pharmacokinetic phenomenon that is related to the drug's
metabolism in the liver. After oral medications are absorbed from the
gastrointestinal tract, the drug is carried directly to the liver via the hepatic portal
circulation, where hepatic inactivation occurs and reduces the bioavailability
(strength/concentration) of the drug.
The healthcare provider prescribes naproxen (Naproxen) twice daily for a client
with osteoarthritis of the hands. The client tells the nurse that the drug does not
seem to be effective after three weeks. Which is the best response for the nurse to
provide?
A. The frequency of the dosing is necessary to increase the effectiveness.
B. Therapeutic blood levels of this drug are reached in 4 to 6 weeks.
C. Another type of nonsteroidal antiinflammatory drug may be indicated.
D. Systemic corticosteroids are the next drugs of choice for pain relief. - ANS... -
C. Another type of nonsteroidal antiinflammatory drug may be indicated.
,Individual responses to nonsteroidal antiinflammatory drugs are vary from person
to person, so another nonsteroidal antiinflammatory drug (NSAID) may be
indicated for this particular client.
After abdominal surgery, a client is prescribed low molecular weight heparin
(LMWH). During administration of the medication, the client asks the nurse the
reason for the medication. Which is the best response for the nurse to provide the
client?
A. This medication is given to prevent blood clot formation.
B. This medication enhances antibiotics to prevent infection.
C. This medication dissolves clots that develop in the legs.
D. This medication enhances the healing of wounds. - ANS... -A. This medication
is given to prevent blood clot formation.
A 43-year-old female client is prescribed thyroid replacement hormone following a
thyroidectomy. Which adverse effects should the nurse instruct the client to report
immediately to the healthcare provider?
A. Tinnitus and dizziness.
B. Tachycardia and chest pain.
C. Dry skin and intolerance to cold.
D. Weight gain and increased appetite. - ANS... -B. Tachycardia and chest pain.
Thyroid replacement hormone increases the metabolic rate of all tissues. Common
signs and symptoms of toxicity include tachycardia and chest pain and should be
reported to the healthcare provider immediately.
A client prescribed albuterol tablets reports nausea every evening with the 9:00
p.m. dose. Which action should the nurse perform to alleviate this side effect?
A. Change the time of the dose.
B. Hold the 9 p.m. dose.
C. Administer the dose with a snack.
D. Offer an antiemetic with the dose. - ANS... -C. Administer the dose with a
snack.
Administering oral doses of albuterol with food helps minimize gastrointestinal
discomfort such as nausea.
, A client is prescribed ampicillin sodium (Omnipen) for a sinus infection. The nurse
should instruct the client to notify the healthcare provider immediately if which
symptom occurs?
A. Rash.
B. Nausea.
C. Headache.
D. Dizziness - ANS... -A. Rash.
Rash is the most common adverse effect of all penicillins, indicating an allergy to
the medication that could result in anaphylactic shock, a medical emergency.
A peak and trough level is prescribed for a client receiving antibiotic therapy.
When should the nurse should obtain the trough level?
A. Sixty minutes after the antibiotic dose is administered.
B. Immediately before the next antibiotic dose is given.
C. Upon completion of the prescribed antibiotic regime.
D. An hour before the next antibiotic dose is given. - ANS... -B. Immediately
before the next antibiotic dose is given.
Trough levels are drawn when the blood level is at its lowest, which is typically
just before the next dose is given.
The nurse is caring for a client who has taken atenolol for 2 years. The healthcare
provider recently changed the medication to enalapril to manage the client's blood
pressure. Which instruction should the nurse provide the client regarding the new
medication?
A. Take the medication at bedtime.
B. Report presence of increased bruising.
C. Check pulse before taking medication.
D. Rise slowly when getting out of bed or chair. - ANS... -D. Rise slowly when
getting out of bed or chair.
The client's new medication is an angiotensin-converting enzyme (ACE) inhibitor,
which has the side effect oforthostatic hypotension. Instructing the client to rise
slowly from a sitting or lying down position is important to teach the client to
avoid dizziness and potentially falling.
A female client calls the clinic and talks with the nurse to inquire about a possible
reaction after taking amoxicillin for 5 days. She reports having vaginal discomfort,
