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NR 283 Exam 2 (Latest 2026/2027 Update) | Respiratory, Cardiac, Hematologic & Oncologic Disorders | Pathophysiology Comprehensive Review | Exam Questions & Answers | Grade A+

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This document contains a comprehensive Exam 2 review for NR 283 Pathophysiology, covering essential disease processes commonly tested in nursing programs. Topics include respiratory disorders such as asthma, COPD, pneumonia, and respiratory failure, focusing on impaired ventilation, gas exchange, and hypoxia. It also includes cardiac disorders such as hypertension, coronary artery disease, heart failure, and dysrhythmias, emphasizing perfusion, cardiac output, and hemodynamic changes. Hematologic disorders are covered, including anemia, clotting disorders, and blood dyscrasias, focusing on oxygen-carrying capacity, coagulation pathways, and related complications. Oncologic disorders include cancer development, staging, metastasis, and treatment modalities such as chemotherapy and radiation therapy, with emphasis on cellular changes and systemic effects. Additional content includes interpretation of laboratory findings, disease progression, and system-based clinical correlation. The material also emphasizes clinical reasoning, prioritization of care, and evidence-based decision-making frameworks such as ABCs and Maslow’s hierarchy. The content is designed to strengthen pathophysiology knowledge, improve clinical reasoning, and support exam readiness using structured, high-yield review aligned with the 2026/2027 curriculum. Keywords: NR 283 exam 2 respiratory cardiac hematologic oncologic asthma COPD pneumonia heart failure CAD anemia clotting disorders cancer metastasis chemotherapy radiation therapy gas exchange perfusion clinical reasoning

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NR 283 Exam 2: (Latest 2026/2027 Update) Respiratory Disorders, Cardiac
Conditions, Hematology, Oncology | Q&A | Grade A | 100% Correct (Verified
Answers)
COMPREHENSIVE PATHOPHYSIOLOGY REVIEW



SUBJECT SOURCE FORMAT
Pathophysiology / Respiratory / NR 283 Exam 2 2026/2027 Q&A Guide with Clinical Rationale
Cardiac / Hematology / Oncology


Q1

In a burn injury, the Rule of Nines is used to estimate:

CORRECT ANSWER Total body surface area burned

CLINICAL RATIONALE

● The Rule of Nines assigns percentage values to body regions (head 9%, each arm 9%, each leg 18%, anterior trunk
18%, posterior trunk 18%, perineum 1%).
● Used to guide fluid resuscitation in burn patients (Parkland formula).
● Modified for pediatric patients due to proportionally larger head size.


Q2

The nurse is aware that hypercapnia can lead to which of the following?

CORRECT ANSWER Respiratory acidosis

CLINICAL RATIONALE

● Hypercapnia is elevated CO2 (>45 mmHg).
● CO2 is an acid; increased CO2 causes pH to drop (acidosis).
● Causes: hypoventilation (COPD, narcotic overdose, chest injury, neuromuscular disorders).


Q3

A patient's arterial blood gas reveals decreased carbon dioxide levels. What is the most likely cause of
this situation?

CORRECT ANSWER Hyperventilation

CLINICAL RATIONALE

● Hyperventilation decreases CO2 (respiratory alkalosis).
● Causes: anxiety/panic attack, pain, hypoxia, pulmonary embolism, mechanical overventilation.
● Symptoms: lightheadedness, perioral numbness, tingling of extremities.

, Q4

What lab value would the nurse expect in a patient who has sustained trauma to the lungs and chest wall
and is experiencing respiratory failure?

CORRECT ANSWER Elevated PaCO2

CLINICAL RATIONALE

● Respiratory failure is inability to maintain adequate gas exchange.
● Type II respiratory failure (hypercapnic): PaCO2 >45 with pH <7.35.
● Chest wall trauma (flail chest, rib fractures) impairs ventilation → CO2 retention.


Q5

A 10-year-old develops pneumonia. Physical exam reveals subcostal and intercostal contractions. The
child reports that breathing is difficult with feeling that "I cannot get enough air." What term should the
nurse use to document this condition?

CORRECT ANSWER Dyspnea

CLINICAL RATIONALE
● Dyspnea is subjective sensation of difficulty breathing (patient's perception).
● Retractions (subcostal, intercostal, suprasternal) indicate increased work of breathing.
● Pneumonia causes inflammation, consolidation, and decreased lung compliance.


Q6

A 50 year old presents with hypotension, hypoxemia, and tracheal deviation to the left. Tests reveal that
the air pressure in the pleural cavity exceeds barometric pressure in the atmosphere. Based upon these
assessment findings, what does the nurse suspect the patient is experiencing?

CORRECT ANSWER Tension Pneumothorax

CLINICAL RATIONALE

● Tension pneumothorax is life-threatening (air trapped in pleural space, shifting mediastinum).
● Hallmarks: tracheal deviation away from affected side, hypotension, distended neck veins.
● Immediate treatment: needle decompression (second intercostal space, midclavicular line).


Q7

A nurse is caring for a client who has emphysema. Which of the following findings should the nurse
expect to assess in this client?

CORRECT ANSWER Dyspnea, Barrel chest, and Hypocapnia (low CO2)

CLINICAL RATIONALE

● Emphysema causes air trapping → barrel chest (increased AP diameter).
● Early/mild emphysema causes hypocapnia due to hyperventilation (low CO2).
● Late/advanced emphysema may cause hypercapnia due to fatigue and hypoventilation.

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