COMPLETE QUESTIONS AND CORRECT
ANSWERS GRADED A+
◉ autograft.
Answer: Transplant from one part of body to another part of same
body. Example: Skin...not used for organs.
◉ heterograft (xenograft.
Answer: Transplant tissue between 2 species. Example: Porcine skin
graft or baboon heart. Temporary transplants d/t rapid tissue
rejection.
◉ allograft (homograft).
Answer: Tissue transplant between 2 members of same species.
Useful for organ/tissue transplants. Triggers immune reaction that
will cause graft reject. Allografts can be obtained from live or
cadaver donors.
◉ isograft.
Answer: tissue transplant between identical twins
◉ living donor.
,Answer: Person who volunteers to donate an organ, part of an organ
or hematopoietic stem cells to another person, while alive. Ideally,
donor and recipient are related (immediate family)
Increased histocompatibility with less rejection and a longer graft
life.
◉ cadaver donor.
Answer: Organs and or tissues are recovered after death Usually due
to a traumatic event or sudden death.
◉ cardiac death donor.
Answer: Termination of cardiac and respiratory function. Tissues
limited to: heart valves, corneas, eyes, saphenous veins, skin and
bones. Tissues are recovered 12 - 24 hours after declaration of
death.
◉ brain death donors.
Answer: Cessation of entire brain and brainstem function. Most
donors are brain death donors. Solid organs include: kidneys, lungs,
heart, liver, pancreas, small
bowel.
◉ uniform anatomincal grist act (UAGA).
,Answer: Authorizes the donation of all or part of the human body
following death for research, transplantation and education. Sets
guidelines for who can donate, how donation is carried out and who
receives the donation. Provides for a donor card as a means for
individuals to convey wishes to
be a donor (drivers license in Ohio). Includes liability protection for
health care providers. Required-Request - hospitals are responsible
for ID-ing potential donors. Penalties or administrative actions if do
not!.
◉ required request.
Answer: - hospitals are responsible for ID-ing potential donors.
Penalties or administrative actions if do not!.
◉ national organ transplant act.
Answer: Set up national Organ Procurement and Transplantation
Network (OPTN). National registries to track potential recipients as
well as post-transplantation organ recipients. Provides for a national
system to match organs and potential recipients. This act prohibits
selling human organ and tissues.
◉ uniform determination of death act.
Answer: Guidelines for states to establish a legal definition of death.
Definition of Death??. Criteria: Think brain death criteria.....
Confirmatory Tests- MRI, Angiography, EEG. Documenting time of
death Family needs notified of time.
, ◉ defining brain death.
Answer: Brain death is defined as the irreversible loss of all
functions of the brain, including the brainstem. The three essential
findings in brain death are coma, absence of brainstem reflexes, and
apnea. An evaluation for brain death should be considered in
patients who have suffered a massive, irreversible brain injury of
identifiable cause. A patient determined to be brain dead is legally
and clinically dead.The diagnosis of brain death is primarily clinical.
No other tests are required if the full clinical examination, including
each of two assessments of brain stem reflexes and a single apnoea
test, are conclusively performed.
◉ donor management.
Answer: Hemodynamic Instability. Loss of thermoregulation. FLE
instability. Pulmonary Dysfunction. Hematopoietic Dysfunction. Loss
of Endocrine Function.
◉ MAP in transplant.
Answer: 60-110 mmhg.
◉ CVP in transplants.
Answer: 4-12 mmhg.
◉ EF in transplant.