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This document, "APEA Patho Final", covers various topics in pathology, including male reproductive
system disorders (testicular torsion, epididymis function), cardiovascular system conditions (myocardial
infarction, heart failure), and musculoskeletal disorders (gout, slipped capital femoral epiphysis). The
document provides 537 questions with correct answers and detailed explanations, serving as a study aid
for students to review and understand these concepts. By utilizing this resource, students can
thoroughly review and reinforce their knowledge, aiding in exam preparation and comprehension of key
pathology concepts.
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EXAM QUESTIONS
QUESTION 1
The structure that aids in the storage and transport of sperm cells and facilitates maturation of sperm
is the
CORRECT ANSWER
epididymis
RATIONALE: The epididymis plays a crucial role in the maturation and storage of sperm cells, as it provides a suitable
environment for sperm to mature and gain the ability to fertilize an egg, a process that typically occurs over several
weeks. This structure is specifically designed to facilitate the transportation of sperm from the testes, allowing them to
be stored and matured before being released for reproduction.
QUESTION 2
Within what time frame should a patient with testicular torsion be treated?
CORRECT ANSWER
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, 6-12 hours
RATIONALE: Prompt treatment of testicular torsion within 6-12 hours is crucial because the testicle's blood supply is
severely compromised, making prompt surgical intervention necessary to salvage the affected testicle and prevent
permanent damage or loss. The shorter the time elapsed before treatment, the higher the chances of successful torsion
detorsion and preservation of the testicle.
QUESTION 3
The most important prerequisites for penile erection are adequate arterial flow and:
CORRECT ANSWER
nitric oxide
RATIONALE: Nitric oxide is the correct answer because it plays a crucial role in the relaxation of smooth muscle cells in
the corpus cavernosum, allowing for increased blood flow and penile erection. The release of nitric oxide from the
endothelial cells lining the blood vessels triggers the smooth muscle relaxation, which is essential for the initiation and
maintenance of an erection.
QUESTION 4
A noncommunicating hydrocele is NOT caused by
CORRECT ANSWER
genetics
RATIONALE: A noncommunicating hydrocele is not caused by genetics because it is not a congenital condition, but
rather a type of hydrocele that occurs due to the blockage of lymphatic vessels or other local factors. The term
"noncommunicating" indicates that the fluid accumulation is isolated to one location and not connected to the scrotum's
communication with the abdominal cavity, ruling out genetic factors as the primary cause.
QUESTION 5
During examination of a 3-month-old child, transillumination identifies fluid in the scrotal sac. The NP
diagnoses:
CORRECT ANSWER
hydrocele
RATIONALE: A hydrocele is the correct diagnosis because transillumination, a test that uses light to detect fluid
accumulation, indicates the presence of fluid in the scrotal sac, which is a characteristic of a hydrocele. This condition
occurs when fluid accumulates in the tunica vaginalis, a thin layer of tissue surrounding the testicles, and is common in
infants, often resolving on its own within the first year of life.
QUESTION 6
Alpha blockers are recommended in the treatment of benign prostatic hyperplasia because they:
CORRECT ANSWER
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, relax the smooth muscle of the prostate
RATIONALE: Alpha blockers work by relaxing the smooth muscle of the prostate, which allows for easier urination by
reducing the physical resistance to urine flow. This is beneficial in treating benign prostatic hyperplasia because it
alleviates the symptoms associated with the enlarged prostate, such as difficulty starting or maintaining urination.
QUESTION 7
Which one of the following conditions occurs when a testicle rotates on the long axis in the tunica
vaginalis?
CORRECT ANSWER
Testicular torsion
RATIONALE: Testicular torsion occurs when the spermatic cord, which supplies blood to the testicle, becomes twisted,
cutting off its blood supply. This twisting motion causes the testicle to rotate on its long axis, resulting in the condition,
which is a medical emergency that requires immediate attention.
QUESTION 8
Which congenital disorder of the penis results from embryologic defects in the development of the
urethral groove and penile urethra?
CORRECT ANSWER
Hypospadias
RATIONALE: Hypospadias is the correct answer because it is a congenital disorder of the penis that occurs when the
urethral groove and penile urethra fail to properly develop during embryologic formation, resulting in an abnormal
opening of the urethra on the underside of the penis. This occurs due to disruptions in the normal process of urethral
development, which is essential for the proper formation of the penis and its associated structures.
QUESTION 9
Which one of the following is NOT a cause of subacute epididymitis?
CORRECT ANSWER
Urinary tract infection
RATIONALE: Urinary tract infection is the correct answer because subacute epididymitis is typically caused by sexually
transmitted infections such as Chlamydia or gonorrhea, or by urethral reflux, which are not directly related to urinary
tract infections. In contrast, urinary tract infections often cause symptoms such as dysuria and frequency, which are not
typically associated with subacute epididymitis.
QUESTION 10
In which condition is the cremasteric reflex absent?
CORRECT ANSWER
Testicular torsion
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, RATIONALE: The cremasteric reflex is a normal physiological response where the cremaster muscle contracts in
response to stroking the skin of the inner thigh, causing the testes to elevate. In testicular torsion, the cremasteric
reflex is typically absent due to the compromised blood supply and nerve damage caused by the twisted spermatic cord,
which prevents the normal contraction of the cremaster muscle.
QUESTION 11
Gynecomastia is caused by:
CORRECT ANSWER
estrogen-androgen imbalance
RATIONALE: Gynecomastia, a condition characterized by the enlargement of breast tissue in males, is primarily caused
by an imbalance of sex hormones, where the levels of estrogen (the female sex hormone) surpass those of androgen
(the male sex hormone). This hormonal imbalance disrupts the normal development of breast tissue in males, leading to
the characteristic symptoms of gynecomastia.
QUESTION 12
An elongated cordlike structure on the posterior border of the testes that is responsible for the
storage, transport, and maturation of sperm is the:
CORRECT ANSWER
epididymis
RATIONALE: The epididymis is the correct answer because it is specifically located on the posterior border of the testes,
where it performs the critical functions of storing, transporting, and maturing sperm after they are released from the
testes. This unique combination of anatomical location and physiological function makes the epididymis essential for the
reproductive process and the correct answer to the question.
QUESTION 13
The most likely cause of epididymitis in men younger than 35 is:
CORRECT ANSWER
Chlamydia trachomatis
RATIONALE: Chlamydia trachomatis is a sexually transmitted bacterium that commonly causes urethritis in young men,
leading to secondary epididymitis due to ascending infection from the urethra. The high prevalence of Chlamydia
trachomatis in sexually active young adults, combined with its tropism for the urogenital tract, makes it the most likely
cause of epididymitis in men younger than 35.
QUESTION 14
The cremasteric reflex assesses a 6-month-old patient for:
CORRECT ANSWER
retractile testicles
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