ATI RN Pharmacology Proctored Exam Retake 2023/2026 with
NGN 180 Verified Questions & 100% Verified Answers
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Table of Contents
1. Foundations of Pharmacology – 20 Questions
2. Cardiovascular & Hematologic Medications – 25 Questions
3. Respiratory & Endocrine Medications – 20 Questions
4. Neurological & Psychiatric Medications – 25 Questions
5. Gastrointestinal & Genitourinary Medications – 15 Questions
6. Pain Management, Musculoskeletal & Antibiotics – 25 Questions
7. Maternal, Pediatric & Lifespan Considerations – 15 Questions
8. Medication Administration & Safety – 20 Questions
9. NGN Case Studies – 15 Questions
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SECTION 1: FOUNDATIONS OF PHARMACOLOGY (20 Questions)
Question 1: A nurse is administering IV push ondansetron. Which finding requires immediate
intervention?
A) Headache
B) Constipation
C) Prolonged QT interval on ECG
,D) Drowsiness
Answer: C) Prolonged QT interval on ECG
Rationale: Ondansetron (5-HT3 antagonist) causes dose-dependent QT prolongation, increasing
the risk of torsades de pointes. Monitor ECG, especially in patients with electrolyte
abnormalities.
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Question 2: A client receiving IV gentamicin has a trough level of 2.4 mcg/mL (therapeutic range
0.5-2.0). What is the nurse's priority action?
A) Administer the next dose as scheduled
B) Hold the next dose and notify the provider
C) Increase the IV fluid rate
D) Obtain a peak level
Answer: B) Hold the next dose and notify the provider
Rationale: Elevated trough (>2 mcg/mL) indicates drug accumulation and increased risk of
nephrotoxicity and ototoxicity. Hold the next dose and notify the provider for dose adjustment.
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Question 3: A nurse is reviewing a client's medications. Which combination increases the risk of
bleeding?
A) Warfarin and acetaminophen
,B) Clopidogrel and omeprazole
C) Enoxaparin and aspirin
D) Rivaroxaban and digoxin
Answer: C) Enoxaparin and aspirin
Rationale: Enoxaparin (anticoagulant) combined with aspirin (antiplatelet) significantly
increases bleeding risk. This combination should be avoided unless absolutely necessary.
Omeprazole reduces clopidogrel effectiveness, but this does not increase bleeding risk.
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Question 4: A client is prescribed metoclopramide. The client reports involuntary facial
movements. What is the nurse's priority action?
A) Administer benztropine
B) Hold the medication and notify the provider
C) Document the finding and continue the medication
D) Increase the dose of metoclopramide
Answer: B) Hold the medication and notify the provider
Rationale: Involuntary facial movements indicate tardive dyskinesia, an extrapyramidal
symptom caused by metoclopramide. The medication should be held and the provider notified
immediately.
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, Question 5: A nurse is administering IV push ondansetron. Which assessment is most important
before administration?
A) Blood pressure
B) QT interval on ECG
C) Respiratory rate
D) Temperature
Answer: B) QT interval on ECG
Rationale: Ondansetron can cause QT prolongation, increasing the risk of torsades de pointes.
Baseline ECG should be reviewed, and electrolyte imbalances corrected before administration.
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Question 6: A client is prescribed metoclopramide. Which finding requires immediate
intervention?
A) Headache
B) Diarrhea
C) Involuntary facial movements
D) Nausea
Answer: C) Involuntary facial movements
Rationale: Involuntary facial movements indicate tardive dyskinesia, which may be irreversible if
not addressed promptly. This requires immediate discontinuation of metoclopramide.
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NGN 180 Verified Questions & 100% Verified Answers
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Table of Contents
1. Foundations of Pharmacology – 20 Questions
2. Cardiovascular & Hematologic Medications – 25 Questions
3. Respiratory & Endocrine Medications – 20 Questions
4. Neurological & Psychiatric Medications – 25 Questions
5. Gastrointestinal & Genitourinary Medications – 15 Questions
6. Pain Management, Musculoskeletal & Antibiotics – 25 Questions
7. Maternal, Pediatric & Lifespan Considerations – 15 Questions
8. Medication Administration & Safety – 20 Questions
9. NGN Case Studies – 15 Questions
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SECTION 1: FOUNDATIONS OF PHARMACOLOGY (20 Questions)
Question 1: A nurse is administering IV push ondansetron. Which finding requires immediate
intervention?
A) Headache
B) Constipation
C) Prolonged QT interval on ECG
,D) Drowsiness
Answer: C) Prolonged QT interval on ECG
Rationale: Ondansetron (5-HT3 antagonist) causes dose-dependent QT prolongation, increasing
the risk of torsades de pointes. Monitor ECG, especially in patients with electrolyte
abnormalities.
---
Question 2: A client receiving IV gentamicin has a trough level of 2.4 mcg/mL (therapeutic range
0.5-2.0). What is the nurse's priority action?
A) Administer the next dose as scheduled
B) Hold the next dose and notify the provider
C) Increase the IV fluid rate
D) Obtain a peak level
Answer: B) Hold the next dose and notify the provider
Rationale: Elevated trough (>2 mcg/mL) indicates drug accumulation and increased risk of
nephrotoxicity and ototoxicity. Hold the next dose and notify the provider for dose adjustment.
---
Question 3: A nurse is reviewing a client's medications. Which combination increases the risk of
bleeding?
A) Warfarin and acetaminophen
,B) Clopidogrel and omeprazole
C) Enoxaparin and aspirin
D) Rivaroxaban and digoxin
Answer: C) Enoxaparin and aspirin
Rationale: Enoxaparin (anticoagulant) combined with aspirin (antiplatelet) significantly
increases bleeding risk. This combination should be avoided unless absolutely necessary.
Omeprazole reduces clopidogrel effectiveness, but this does not increase bleeding risk.
---
Question 4: A client is prescribed metoclopramide. The client reports involuntary facial
movements. What is the nurse's priority action?
A) Administer benztropine
B) Hold the medication and notify the provider
C) Document the finding and continue the medication
D) Increase the dose of metoclopramide
Answer: B) Hold the medication and notify the provider
Rationale: Involuntary facial movements indicate tardive dyskinesia, an extrapyramidal
symptom caused by metoclopramide. The medication should be held and the provider notified
immediately.
---
, Question 5: A nurse is administering IV push ondansetron. Which assessment is most important
before administration?
A) Blood pressure
B) QT interval on ECG
C) Respiratory rate
D) Temperature
Answer: B) QT interval on ECG
Rationale: Ondansetron can cause QT prolongation, increasing the risk of torsades de pointes.
Baseline ECG should be reviewed, and electrolyte imbalances corrected before administration.
---
Question 6: A client is prescribed metoclopramide. Which finding requires immediate
intervention?
A) Headache
B) Diarrhea
C) Involuntary facial movements
D) Nausea
Answer: C) Involuntary facial movements
Rationale: Involuntary facial movements indicate tardive dyskinesia, which may be irreversible if
not addressed promptly. This requires immediate discontinuation of metoclopramide.
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