and Physician Assistants (2nd Edition Rosenthal Test Bank)
Advanced Final Exam Study Guide
2026/2027
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Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 30. A patient
is receiving intravenous gentamicin. A serum drug test reveals toxic levels. The
dosing is correct, and this medication has been tolerated by this patient in the
past. Which could be a probable cause of the test result?
c. The patient is taking another medication that binds to serum albumin.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 31. A patient
reports becoming "immune" to a medication because it no longer works to
alleviate symptoms. The nurse recognizes that this decreased effectiveness is
likely caused by:
c. Desensitization of receptor sites by continual exposure to the drug.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 32. A patient
who is taking morphine for pain asks the nurse how a pain medication can also
cause constipation. What does the nurse know about morphine?
d. It is selective to receptors that regulate more than one body process.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 33. The nurse
is administering morning medications. The nurse gives a patient multiple
medications, two of which compete for plasma albumin receptor sites. As a result
of this concurrent administration, the nurse can anticipate that what might occur?
a. Binding of one or both agents will be reduced.
b. Plasma levels of free drug will rise.
d. The increase in free drug will intensify effects.
Ch 4 Pharmacokinetics, Pharmacodynamics, and Drug Interactions 34. When
administering medications to infants, it is important to remember which of the
following?
,b. Immaturity of renal function in infancy causes infants to excrete drugs less efficiently.
<br> c. Infants have immature livers, which slows drug metabolism. <br> d. Infants are
more sensitive to medications that act on the central nervous system (CNS).
Ch 5 Adverse Drug Reactions and Medication Errors 35. A nursing student is
preparing to give a medication that has a boxed warning. The student asks the
nurse what this means. What will the nurse explain about boxed warnings?
c. They alert prescribers to measures to mitigate potential harm from side effects.
Ch 5 Adverse Drug Reactions and Medication Errors 36. A nurse is preparing to
administer a drug. Upon reading the medication guide, the nurse notes that the
drug has been linked to symptoms of Parkinson disease in some patients. What
will the nurse do?
b. Observe the patient closely for such symptoms and prepare to treat them if needed.
Ch 5 Adverse Drug Reactions and Medication Errors 37. Which patients are at
increased risk for adverse drug events? Select all that apply.
a. A 2-month-old infant taking a medication for gastroesophageal reflux disease
c. A 40-year-old male who is intubated in the intensive care unit and taking antibiotics
and cardiac medications
e. An 80-year-old male taking medications for COPD
Ch 5 Adverse Drug Reactions and Medication Errors 38. A nurse provides
teaching to a patient who will begin taking a drug with a known risk of
hepatotoxicity. Which statement by the patient indicates a need for further
teaching?
d. "Routine testing and early detection of problems will prevent liver failure."
Ch 5 Adverse Drug Reactions and Medication Errors 39. A nurse is reviewing a
medication administration record before administering medications. Which order
will the nurse implement?
d. Furosemide [Lasix] 20 mg PO daily
Ch 5 Adverse Drug Reactions and Medication Errors 40. A patient is given a new
medication and reports nausea within an hour after taking the drug. The nurse
consults the drug information manual and learns that nausea is not an expected
adverse effect of this drug. When the next dose is due, what will the nurse do?
a. Administer the drug and tell the patient to report further nausea
Ch 5 Adverse Drug Reactions and Medication Errors 41. A nurse is preparing to
give an antibiotic to a patient who reports being allergic to antibiotics. Before
giving the medication, what will the nurse do first?
a. Ask whether the patient has taken this antibiotic for other infections
Ch 5 Adverse Drug Reactions and Medication Errors 42. A patient is taking
sertraline [Zoloft] for depression, and the provider orders azithromycin
[Zithromax] to treat an infection. What will the nurse do?
a. Contact the provider to discuss an alternative to azithromycin.
Ch 5 Adverse Drug Reactions and Medication Errors 43. A patient is given a drug
for the first time and develops shortness of breath. The patient's heart rate is 76
beats/minute, the respiratory rate is 20 breaths/minute, and the blood pressure is
120/70 mm Hg. The nurse checks a drug administration manual to make sure the
correct dose was given and learns that some patients taking the drug experience
shortness of breath. The nurse will contact the provider to report what?
, d. A side effect
Ch 5 Adverse Drug Reactions and Medication Errors 44. Which are effective ways
to help prevent medication errors? Select all that apply.
a. Developing non-punitive approaches to track errors
c. Helping patients to be active, informed members of the healthcare team
e. Using electronic medical order entry systems
Ch 5 Adverse Drug Reactions and Medication Errors 45. A patient is taking a drug
that has known toxic side effects. What will the nurse do?
c. Monitor the function of all organs potentially affected by the drug.
Ch 5 Adverse Drug Reactions and Medication Errors 46. A patient is being
discharged after surgery. During the admission history, the nurse learned that the
patient normally consumes two or three glasses of wine each day. The prescriber
has ordered hydrocodone with acetaminophen [Lortab] for pain. What will the
nurse do?
c. Tell the patient not to drink wine while taking Lortab.
Ch 5 Adverse Drug Reactions and Medication Errors 47. Which actions occur in
90% of fatal medication errors? Select all that apply.
b. Giving a drug intravenously instead of intramuscularly
c. Giving Nasarel instead of Nizoral
e. Writing a prescription illegibly
Ch 6 Individual Variation in Drug Responses 48. A nurse is caring for a woman
with breast cancer who is receiving tamoxifen. A review of this patient's chart
reveals a deficiency of the CYP2D6 gene. The nurse will contact the provider to
suggest:
a. a different medication.
Ch 6 Individual Variation in Drug Responses 49. Which groups of people are
especially sensitive to medication effects? Select all that apply.
a. Older adults
c. Infants
Ch 6 Individual Variation in Drug Responses 50. A post-operative patient who is
worried about pain control will be discharged several days after surgery. The
nurse providing discharge teaching tells the patient that the prescribed Lortab is
not as strong as the morphine the patient was given in the immediate post-
operative period. Which response is the patient likely to experience?
b. A negative placebo effect when taking the medication
Ch 6 Individual Variation in Drug Responses 51. A patient has been taking
narcotic analgesics for chronic pain for several months. The nurse caring for this
patient notes that the prescribed dose is higher than the recommended dose. The
patient has normal vital signs, is awake and alert, and reports mild pain. What
does the nurse recognize about this patient?
c. This patient has developed pharmacodynamic tolerance, which has increased the
minimal effective concentration (MEC) needed for analgesic effect.
Ch 6 Individual Variation in Drug Responses 52. A patient asks a nurse why a
friend who is taking the same drug responds differently to that drug. The nurse
knows that the most common variation in drug response is due to differences in
each patient's: