Page 1 of 88
CVD Quiz | Questions and Answers |
2026 Updated | Graded A+
Q1
Which of the following is the leading cause of death
worldwide as of 2026?
A) Cancer
B) Cardiovascular disease
C) Respiratory infections
D) Diabetes mellitus
Rationale: CVD remains the #1 cause of death globally,
accounting for ~32% of all deaths (WHO data). Ischemic heart
disease and stroke are the top two.
Answer: B
,Page 2 of 88
Q2
The INTERHEART study identified nine modifiable risk factors
that account for approximately what percentage of the
population attributable risk of myocardial infarction?
A) 50%
B) 90%
C) 30%
D) 70%
Rationale: The INTERHEART study (2004) demonstrated that nine
modifiable risk factors (smoking, lipids, hypertension, diabetes,
obesity, diet, physical activity, alcohol, psychosocial factors)
account for >90% of the risk of MI.
Answer: B
Q3
,Page 3 of 88
Which lipoprotein pattern is most strongly associated with
increased risk of atherosclerotic cardiovascular disease
(ASCVD)?
A) High HDL, low LDL
B) High LDL and high small dense LDL particles
C) Low triglycerides
D) High HDL, high LDL
Rationale: Elevated LDL cholesterol, particularly small dense LDL
particles, is highly atherogenic. High HDL is protective.
Answer: B
Q4
A 55-year-old male has a 10-year ASCVD risk of 12%
according to the pooled cohort equation (PCE). According to
2019 ACC/AHA guidelines, he should be considered:
A) Low risk (<5%)
, Page 4 of 88
B) Borderline to intermediate risk; statin therapy is
recommended (≥7.5% is threshold for moderate-intensity statin
in primary prevention)
C) Very high risk
D) No statin needed
Rationale: The 2018/2019 ACC/AHA guidelines recommend
moderate-intensity statin for primary prevention when 10-year
ASCVD risk is ≥7.5% and patient age 40-75.
Answer: B
Q5
Which risk factor has the highest population attributable risk
for coronary heart disease in women?
A) Hypertension
B) Diabetes mellitus
CVD Quiz | Questions and Answers |
2026 Updated | Graded A+
Q1
Which of the following is the leading cause of death
worldwide as of 2026?
A) Cancer
B) Cardiovascular disease
C) Respiratory infections
D) Diabetes mellitus
Rationale: CVD remains the #1 cause of death globally,
accounting for ~32% of all deaths (WHO data). Ischemic heart
disease and stroke are the top two.
Answer: B
,Page 2 of 88
Q2
The INTERHEART study identified nine modifiable risk factors
that account for approximately what percentage of the
population attributable risk of myocardial infarction?
A) 50%
B) 90%
C) 30%
D) 70%
Rationale: The INTERHEART study (2004) demonstrated that nine
modifiable risk factors (smoking, lipids, hypertension, diabetes,
obesity, diet, physical activity, alcohol, psychosocial factors)
account for >90% of the risk of MI.
Answer: B
Q3
,Page 3 of 88
Which lipoprotein pattern is most strongly associated with
increased risk of atherosclerotic cardiovascular disease
(ASCVD)?
A) High HDL, low LDL
B) High LDL and high small dense LDL particles
C) Low triglycerides
D) High HDL, high LDL
Rationale: Elevated LDL cholesterol, particularly small dense LDL
particles, is highly atherogenic. High HDL is protective.
Answer: B
Q4
A 55-year-old male has a 10-year ASCVD risk of 12%
according to the pooled cohort equation (PCE). According to
2019 ACC/AHA guidelines, he should be considered:
A) Low risk (<5%)
, Page 4 of 88
B) Borderline to intermediate risk; statin therapy is
recommended (≥7.5% is threshold for moderate-intensity statin
in primary prevention)
C) Very high risk
D) No statin needed
Rationale: The 2018/2019 ACC/AHA guidelines recommend
moderate-intensity statin for primary prevention when 10-year
ASCVD risk is ≥7.5% and patient age 40-75.
Answer: B
Q5
Which risk factor has the highest population attributable risk
for coronary heart disease in women?
A) Hypertension
B) Diabetes mellitus
