PATHOPHYSIOLOGY 2 EDITION TEST
BANK 2026 COMPLETE QUESTION BANK
WITH RELIABLE SOLUTIONS SUCCESS KIT
GRADED A+
⩥ Describe the function of osteoclasts in bone remodeling?
Answer: Degrades bones to initiate bone remodeling
⩥ What is osteomyelitis?
Answer: Severe pyogenic (pus producing) infection of the bone & local
tissue due to organisms
⩥ What are the ways in which organisms can reach the bone?
Answer: - Bloodstream
- Adjacent soft tissue
- Direct introduction of organism
⩥ Osteomyelitis resulting from organism reaching bone through
adjacent tissue is caused by?
Answer: - Burns
- Sinus disease
,- Trauma
- Malignant tumor necrosis
- Periodontal infection
- Infected pressure ulcer (bedsores)
⩥ Osteomyelitis resulting from a direct introduction of an organism is
caused by?
Answer: - Open fracture
- Penetrating wound
- Surgical contamination
- Insertion of protheses
- Metal plates
- Screws
⩥ Clinical manifestation of osteomyelitis in adults?
Answer: - Fever- Malaise
- Anorexia/ weight loss
- Night sweats
⩥ Clinical manifestation of osteomyelitis in children?
Answer: - High fever & pain
- Redness & swelling at the site of bone involvement
, - Brodie abscess: subacute osteomyelitis
⩥ What happens when osteomyelitis is not managed or treatment is
insufficient?
Answer: Necrotic bone separates from healthy bone into dead segments
leading to sequestra and then chronic osteomyelitis
- Abscess or chronic infection may occur
⩥ What possible issue could arise w/ an involucrum?
Answer: It could prevent successful effects of antibiotics when treating
osteomyelitis
⩥ Why may stopping antibiotic treatment for osteomyelitis too soon
worsen your conditions?
Answer: If the treatment is stopped before the course is finished (4-6
weeks) then this can cause sequestra (necrosis of the bone) causing
chronic osteomyelitis which is hard to treat since antibiotic cannot reach
this area
⩥ For children, where does osteomyelitis occur & why?
Answer: The metaphysis of the long bone b/c it is rich in red marrow
⩥ Why is articular cartilage particularly susceptible to degenerative
changes?