NR565 / NR 565 Final Exam Advanced
Pharmacology Fundamentals Questions and
Answers
In which patient population is Metformin contraindicated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility
C. Alcoholics
What lab value suggests metformin might be contraindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17
A. eGFR <30
What medication is contraindicated to treat diabetes if a patient already has a
cardiac ejection fraction rate of 40%?
A. Second Generation sulfonylureas
B. Thiazolidinediones
C. Dopamine Agonist
,D. Glucosidase Inhibitor
B. Thiazolidinediones
Sabrina is a 35-year-old female who presents with complaints of fatigue, anxiety,
and palpitations. She has a long history of obesity and reports that she is happy
that she has lost 23 pounds in the last 2 months. She also reports that she has
trouble sleeping and her husband complains that she is keeping the house too
cold. Physical exam reveals slight tachycardia at 104 bpm and a slightly enlarged
thyroid. Thyroid testing reveals hyperthyroidism or Grave's disease.
Which of the following agents is the first-line treatment for hyperthyroidism
or Grave's disease?
A. Methimazole
B. Metoprolol
C. Allopurinol
D. Levothyroxine
A. Methimazole
Which of the following medications would be considered the first line of
treatment for a newly diagnosed Diabetic patient with adequate renal and
hepatic function?
A: NovoLog Sliding Scale Insulin
B: Liraglutide (Victoza)
C: Oral Metformin
D: Glipizide
C: Oral Metformin
,Of the following medications, which is most likely to cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones
B. Insulin
Which symptoms are most expected of a patient diagnosed with hypothyroidism?
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema
D. dry skin, brittle hair, fatigue, myxedema
Patients with an increased risk for UTIs and genital infections or an active
diagnosis, should avoid what drug class/es for treatment of Type II Diabetes?
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
D. All of the above.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
, A 45-year-old patient with a history of type 2 diabetes presents to the clinic for a
follow-up appointment. The healthcare provider has prescribed metformin as part
of the treatment plan. Which of the following statements regarding metformin is
correct?
A. Metformin primarily stimulates insulin production from the pancreas.
B. Metformin reduces glucose levels primarily by decreasing insulin resistance.
C. Metformin is associated with a risk of hypoglycemia.
D. Metformin improves insulin sensitivity and reduces hepatic glucose production.
D. Metformin improves insulin sensitivity and reduces hepatic glucose production.
In what part of the body are SGLT-2 (sodium-glucose cotransporter 2) inhibitors
active?
A. Small intestine
B. Pancreas
C. Renal tubules
D. Stomach
C. Renal tubules
Which of the following statements is not true regarding sulfonylureas?
A. Sulfonylureas are safe to prescribe to pregnant and/or breast-feeding women.
B. Patients should be educated about signs and symptoms of hypoglycemia.
Pharmacology Fundamentals Questions and
Answers
In which patient population is Metformin contraindicated in?
A. Diabetics with HA1c < 7.0%
B. Patients older than 50
C. Alcoholics
D. Women suffering from infertility
C. Alcoholics
What lab value suggests metformin might be contraindicated?
A. eGFR <30
B. Crea 0.8
C. WBC 7.8
D. Bun 17
A. eGFR <30
What medication is contraindicated to treat diabetes if a patient already has a
cardiac ejection fraction rate of 40%?
A. Second Generation sulfonylureas
B. Thiazolidinediones
C. Dopamine Agonist
,D. Glucosidase Inhibitor
B. Thiazolidinediones
Sabrina is a 35-year-old female who presents with complaints of fatigue, anxiety,
and palpitations. She has a long history of obesity and reports that she is happy
that she has lost 23 pounds in the last 2 months. She also reports that she has
trouble sleeping and her husband complains that she is keeping the house too
cold. Physical exam reveals slight tachycardia at 104 bpm and a slightly enlarged
thyroid. Thyroid testing reveals hyperthyroidism or Grave's disease.
Which of the following agents is the first-line treatment for hyperthyroidism
or Grave's disease?
A. Methimazole
B. Metoprolol
C. Allopurinol
D. Levothyroxine
A. Methimazole
Which of the following medications would be considered the first line of
treatment for a newly diagnosed Diabetic patient with adequate renal and
hepatic function?
A: NovoLog Sliding Scale Insulin
B: Liraglutide (Victoza)
C: Oral Metformin
D: Glipizide
C: Oral Metformin
,Of the following medications, which is most likely to cause hypoglycemia?
A. Metformin
B. Insulin
C. Incretin mimetics
D. Thiazolidinediones
B. Insulin
Which symptoms are most expected of a patient diagnosed with hypothyroidism?
A. shortness of breath, wheezing, fatigue
B. tachycardia, insomnia, weight loss, goiter
C. irritability, anxiety, dizziness, increased sweating
D. dry pale skin, brittle hair, fatigue, myxedema
D. dry skin, brittle hair, fatigue, myxedema
Patients with an increased risk for UTIs and genital infections or an active
diagnosis, should avoid what drug class/es for treatment of Type II Diabetes?
A. Thiazolidinediones (Glitazones)
B. Biguanide.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
D. All of the above.
C. Sodium-Glucose Cotransporter 2 (SGLT-2) Inhibitors.
, A 45-year-old patient with a history of type 2 diabetes presents to the clinic for a
follow-up appointment. The healthcare provider has prescribed metformin as part
of the treatment plan. Which of the following statements regarding metformin is
correct?
A. Metformin primarily stimulates insulin production from the pancreas.
B. Metformin reduces glucose levels primarily by decreasing insulin resistance.
C. Metformin is associated with a risk of hypoglycemia.
D. Metformin improves insulin sensitivity and reduces hepatic glucose production.
D. Metformin improves insulin sensitivity and reduces hepatic glucose production.
In what part of the body are SGLT-2 (sodium-glucose cotransporter 2) inhibitors
active?
A. Small intestine
B. Pancreas
C. Renal tubules
D. Stomach
C. Renal tubules
Which of the following statements is not true regarding sulfonylureas?
A. Sulfonylureas are safe to prescribe to pregnant and/or breast-feeding women.
B. Patients should be educated about signs and symptoms of hypoglycemia.
