TIETZ FUNDAMENTALS OF CLINICAL
CHEMISTRY AND MOLECULAR DIAGNOSTICS
149 FINAL PAPER 2026 COMPLETE QUESTIONS
ANSWERS PREMIUM STUDY GUIDE
◉ Annotation.
Answer: Biologic information attached to a genomic sequence.
◉ Assembly.
Answer: Reconstruction of short-sequence reads on a scaffold of
reference DNA.
◉ Autosome.
Answer: A non-sex chromosome.
◉ Base pair.
Answer: Complementary base pairing of guanine and cytosine and
adenine and thymine through hydrogen bonding.
◉ Centromere.
Answer: The region of a chromosome between the small and long
arms that is used during mitosis to attach the spindle fibers.
, ◉ Chromatin.
Answer: A structure in the eukaryotic nucleus composed of DNA and
histone proteins.
◉ Chromosome.
Answer: A nucleic acid structure bound by protein containing all or a
portion of an organism's genetic information.
◉ Codon.
Answer: A three-base code found in messenger RNA, used in
translation to specify the amino acid to be incorporated in the
growing polypeptide chain.
◉ Copy number variant (CNV).
Answer: A structural variant of a large region of the genome that has
been deleted or duplicated.
◉ Deletion.
Answer: A DNA sequence that is missing in one sample compared
with another. Deletions may be as small as one nucleotide or as large
as an entire chromosome.
◉ Deoxyribonucleic acid (DNA).
CHEMISTRY AND MOLECULAR DIAGNOSTICS
149 FINAL PAPER 2026 COMPLETE QUESTIONS
ANSWERS PREMIUM STUDY GUIDE
◉ Annotation.
Answer: Biologic information attached to a genomic sequence.
◉ Assembly.
Answer: Reconstruction of short-sequence reads on a scaffold of
reference DNA.
◉ Autosome.
Answer: A non-sex chromosome.
◉ Base pair.
Answer: Complementary base pairing of guanine and cytosine and
adenine and thymine through hydrogen bonding.
◉ Centromere.
Answer: The region of a chromosome between the small and long
arms that is used during mitosis to attach the spindle fibers.
, ◉ Chromatin.
Answer: A structure in the eukaryotic nucleus composed of DNA and
histone proteins.
◉ Chromosome.
Answer: A nucleic acid structure bound by protein containing all or a
portion of an organism's genetic information.
◉ Codon.
Answer: A three-base code found in messenger RNA, used in
translation to specify the amino acid to be incorporated in the
growing polypeptide chain.
◉ Copy number variant (CNV).
Answer: A structural variant of a large region of the genome that has
been deleted or duplicated.
◉ Deletion.
Answer: A DNA sequence that is missing in one sample compared
with another. Deletions may be as small as one nucleotide or as large
as an entire chromosome.
◉ Deoxyribonucleic acid (DNA).
