CHAMBERLAIN COLLEGE OF NURSING
NR 599 Midterm Exam
Nursing Informatics for Advanced Practice
Official Practice Exam - 2026/2027 Edition
50 Questions 90 Minutes 80% Passing Score 5 Sections
TABLE OF CONTENTS
Section 1: Foundations of Nursing Informatics .................. Questions 1-10
Section 2: Information and Knowledge Management .................. Questions 11-20
Section 3: Clinical Information Systems .................. Questions 21-30
Section 4: Data Security, Privacy, and Ethics .................. Questions 31-40
Section 5: Informatics and Quality Improvement .................. Questions 41-50
Answer Key .......................... Last Page
INSTRUCTIONS
This practice exam contains 50 multiple-choice questions divided into 5 sections.
You have 90 minutes to complete the entire exam. A passing score of 80% (40/50) is required.
Each question has four options (A, B, C, D). Select the single best answer for each question.
The correct answer and rationale are provided immediately after each question for study purposes.
The 2026/2027 designation confirms this exam reflects the most current test blueprint and content.
This is an independent practice exam and is not affiliated with or endorsed by Chamberlain University.
NRNR
599599
Nursing
Nursing
Informatics
Informatics
- 2026/2027
- 2026/2027
| Passing
| Passing
Score:
Score:
80%80%
| Page
| Page
1 of1 28
,Section 1: Foundations of Nursing Informatics - 2026/2027
Q1 Question 1 of 50
A 34-year-old nurse practitioner working in a rural primary care clinic is asked by her organization to serve
as the informatics champion for a new EHR implementation. She has no formal informatics training but is
interested in the role. The American Nurses Association (ANA) identifies specific competencies that
distinguish nursing informatics as a specialty. The foundational document that first established nursing
informatics as a recognized specialty within nursing is the:
A. ANA Nursing Informatics: Scope and Standards of Practice published in 1994 and updated in
2015
B. Institute of Medicine report Crossing the Quality Chasm published in 2001
C. Health Information Technology for Economic and Clinical Health (HITECH) Act of 2009
D. American Medical Informatics Association founding charter published in 1988
Correct Answer: A
Rationale:
The ANA published the first Scope and Standards of Nursing Informatics Practice in 1994, formally
recognizing nursing informatics as a specialty within nursing. The IOM report and HITECH Act address
broader healthcare quality and technology adoption, not specialty recognition. AMIA is an interdisciplinary
organization, not a nursing-specific credentialing body.
NRNR
599599
Nursing
Nursing
Informatics
Informatics
- 2026/2027
- 2026/2027
| Passing
| Passing
Score:
Score:
80%80%
| Page
| Page
2 of2 28
, Q2 Question 2 of 50
A 42-year-old clinical nurse specialist is participating in a workflow analysis for her unit before a health
information system upgrade. The project manager references the Systems Development Life Cycle
(SDLC) as the framework guiding the project. During the planning phase of the SDLC, the informatics
nurse should prioritize which activity to ensure the system meets clinical needs?
A. Writing programming code for the user interface modules and database schemas
B. Conducting a needs assessment with end users to define functional requirements and
workflow gaps
C. Performing stress testing and load balancing on the production server environment
D. Creating marketing materials and training schedules for the go-live rollout event
Correct Answer: B
Rationale:
The planning phase of the SDLC focuses on gathering user requirements and defining what the system
must accomplish through needs assessments and workflow analysis. Coding occurs in the development
phase, testing in the testing phase, and training materials in the implementation phase, making each of
those options a mismatch for the planning stage.
Q3 Question 3 of 50
A 29-year-old registered nurse enrolled in a DNP program is studying the DIKW pyramid as a foundational
model in nursing informatics. Her professor asks her to explain the difference between information and
knowledge within this framework. The correct distinction is that information becomes knowledge when:
A. It is stored in a relational database with proper indexing and query optimization
B. It is transmitted electronically between two healthcare information systems using HL7
C. It is synthesized with experience, context, and judgment to produce actionable understanding
D. It is collected directly from patients through standardized assessment instruments
Correct Answer: C
Rationale:
In the DIKW model, knowledge is information that has been combined with experience, context, and
professional judgment to become actionable understanding. Database storage addresses data
management, HL7 transmission addresses interoperability, and patient assessment addresses data
collection, none of which transform information into knowledge.
NRNR
599599
Nursing
Nursing
Informatics
Informatics
- 2026/2027
- 2026/2027
| Passing
| Passing
Score:
Score:
80%80%
| Page
| Page
3 of3 28
NR 599 Midterm Exam
Nursing Informatics for Advanced Practice
Official Practice Exam - 2026/2027 Edition
50 Questions 90 Minutes 80% Passing Score 5 Sections
TABLE OF CONTENTS
Section 1: Foundations of Nursing Informatics .................. Questions 1-10
Section 2: Information and Knowledge Management .................. Questions 11-20
Section 3: Clinical Information Systems .................. Questions 21-30
Section 4: Data Security, Privacy, and Ethics .................. Questions 31-40
Section 5: Informatics and Quality Improvement .................. Questions 41-50
Answer Key .......................... Last Page
INSTRUCTIONS
This practice exam contains 50 multiple-choice questions divided into 5 sections.
You have 90 minutes to complete the entire exam. A passing score of 80% (40/50) is required.
Each question has four options (A, B, C, D). Select the single best answer for each question.
The correct answer and rationale are provided immediately after each question for study purposes.
The 2026/2027 designation confirms this exam reflects the most current test blueprint and content.
This is an independent practice exam and is not affiliated with or endorsed by Chamberlain University.
NRNR
599599
Nursing
Nursing
Informatics
Informatics
- 2026/2027
- 2026/2027
| Passing
| Passing
Score:
Score:
80%80%
| Page
| Page
1 of1 28
,Section 1: Foundations of Nursing Informatics - 2026/2027
Q1 Question 1 of 50
A 34-year-old nurse practitioner working in a rural primary care clinic is asked by her organization to serve
as the informatics champion for a new EHR implementation. She has no formal informatics training but is
interested in the role. The American Nurses Association (ANA) identifies specific competencies that
distinguish nursing informatics as a specialty. The foundational document that first established nursing
informatics as a recognized specialty within nursing is the:
A. ANA Nursing Informatics: Scope and Standards of Practice published in 1994 and updated in
2015
B. Institute of Medicine report Crossing the Quality Chasm published in 2001
C. Health Information Technology for Economic and Clinical Health (HITECH) Act of 2009
D. American Medical Informatics Association founding charter published in 1988
Correct Answer: A
Rationale:
The ANA published the first Scope and Standards of Nursing Informatics Practice in 1994, formally
recognizing nursing informatics as a specialty within nursing. The IOM report and HITECH Act address
broader healthcare quality and technology adoption, not specialty recognition. AMIA is an interdisciplinary
organization, not a nursing-specific credentialing body.
NRNR
599599
Nursing
Nursing
Informatics
Informatics
- 2026/2027
- 2026/2027
| Passing
| Passing
Score:
Score:
80%80%
| Page
| Page
2 of2 28
, Q2 Question 2 of 50
A 42-year-old clinical nurse specialist is participating in a workflow analysis for her unit before a health
information system upgrade. The project manager references the Systems Development Life Cycle
(SDLC) as the framework guiding the project. During the planning phase of the SDLC, the informatics
nurse should prioritize which activity to ensure the system meets clinical needs?
A. Writing programming code for the user interface modules and database schemas
B. Conducting a needs assessment with end users to define functional requirements and
workflow gaps
C. Performing stress testing and load balancing on the production server environment
D. Creating marketing materials and training schedules for the go-live rollout event
Correct Answer: B
Rationale:
The planning phase of the SDLC focuses on gathering user requirements and defining what the system
must accomplish through needs assessments and workflow analysis. Coding occurs in the development
phase, testing in the testing phase, and training materials in the implementation phase, making each of
those options a mismatch for the planning stage.
Q3 Question 3 of 50
A 29-year-old registered nurse enrolled in a DNP program is studying the DIKW pyramid as a foundational
model in nursing informatics. Her professor asks her to explain the difference between information and
knowledge within this framework. The correct distinction is that information becomes knowledge when:
A. It is stored in a relational database with proper indexing and query optimization
B. It is transmitted electronically between two healthcare information systems using HL7
C. It is synthesized with experience, context, and judgment to produce actionable understanding
D. It is collected directly from patients through standardized assessment instruments
Correct Answer: C
Rationale:
In the DIKW model, knowledge is information that has been combined with experience, context, and
professional judgment to become actionable understanding. Database storage addresses data
management, HL7 transmission addresses interoperability, and patient assessment addresses data
collection, none of which transform information into knowledge.
NRNR
599599
Nursing
Nursing
Informatics
Informatics
- 2026/2027
- 2026/2027
| Passing
| Passing
Score:
Score:
80%80%
| Page
| Page
3 of3 28
