CHAMBERLAIN UNIVERSITY | COLLEGE OF NURSING
NR 601 Midterm Exam
Study Guide Weeks 1-4
Official Practice Exam -- 2026/2027 Edition
75 90 80% Multiple Choice
Questions Minutes Passing Score Format
TABLE OF CONTENTS
Section 1: Health Promotion & Disease Prevention .............. Questions 1-15
Section 2: Clinical Assessment & Diagnostic Reasoning ....... Questions 16-30
Section 3: Acute & Episodic Condition Management ............. Questions 31-45
Section 4: Chronic Disease Management ........................ Questions 46-60
Section 5: Pharmacology & Evidence-Based Practice ............ Questions 61-75
EXAM INSTRUCTIONS
This practice exam contains 75 multiple-choice questions divided into five sections. You have 90 minutes to
complete the entire exam. A passing score of 80% (60 correct out of 75) is required. Each question has four
answer choices (A through D); select the single best answer. No points are deducted for incorrect responses, so it
is advantageous to answer every question. Read each scenario carefully before selecting your response. Review
the rationale provided after each answer to reinforce your understanding of key concepts covered in Weeks 1
through 4 of NR 601.
TIPS FOR SUCCESS
1. Read the entire scenario and all four options before selecting an answer.
2. Eliminate obviously incorrect choices first to improve your odds.
3. Pay close attention to age-specific and setting-specific clues in each scenario.
4. The rationale after each question explains why the correct answer is right and why a
top distractor is wrong -- use these to deepen your understanding.
5. Time management: aim to spend no more than 72 seconds per question on average.
NR 601 Midterm -- 2026/2027 | Passing Score: 80% | Page 1 of ?
,Section 1: Health Promotion & Disease Prevention | 2026/2027
Q1 Question 1 of 75
A 52-year-old African American man presents for an annual wellness visit. He has no
significant past medical history and takes no medications. His blood pressure is 128/82
mmHg, BMI is 27, and he reports no exercise routine. According to USPSTF guidelines,
which screening should be prioritized at this visit?
A. Prostate-specific antigen testing for prostate cancer
B. Lipid panel screening for cardiovascular risk assessment
C. Colonoscopy referral beginning at age 45
D. Annual low-dose CT scan for lung cancer
Correct Answer: B
Rationale:
The USPSTF recommends lipid panel screening for cardiovascular risk assessment in men aged 40-75,
especially with risk factors like elevated BMI and sedentary lifestyle. Prostate cancer screening requires
shared decision-making, not automatic prioritization. Colonoscopy at 45 is important but lipid screening
addresses more immediate modifiable risk. Low-dose CT requires a significant smoking history, which this
patient lacks.
NRNR
601
601
Midterm
Midterm
-- 2026/2027
-- 2026/2027| Passing
| Passing
Score:
Score:
80%
80%| Page
| Page
2 of
2 ?
,Q2 Question 2 of 75
A 45-year-old woman with a family history of breast cancer in her mother at age 48 asks
about mammography screening. She has no breast symptoms and clinical breast exam is
unremarkable. Which recommendation aligns with current USPSTF guidelines for this
patient?
A. Begin mammography screening now and repeat every two years
B. Defer mammography until age 50 because her personal risk is average
C. Begin annual mammography immediately and refer for genetic counseling
D. Recommend breast MRI instead of mammography for high-risk screening
Correct Answer: A
Rationale:
The USPSTF recommends biennial mammography starting at age 40 for average-risk women, and this patient
with a first-degree relative diagnosed before age 50 may benefit from earlier initiation. Deferring to 50 ignores
her family history. Annual mammography and genetic counseling are not first-line USPSTF recommendations
without additional risk factors. Breast MRI is reserved for very high-risk patients, such as BRCA carriers.
Q3 Question 3 of 75
A 60-year-old postmenopausal woman with a T-score of -2.7 at the femoral neck is
counseled about osteoporosis management. She has no fracture history and takes calcium
600 mg twice daily. Which lifestyle modification is most important to emphasize during this
visit?
A. Increasing dietary calcium intake to 2,000 mg per day from food sources alone
B. Weight-bearing and resistance exercise at least 3-4 times per week
C. Avoiding all sun exposure to reduce melanoma risk
D. Daily passive range-of-motion exercises for joint flexibility
Correct Answer: B
Rationale:
Weight-bearing and resistance exercise is the most critical lifestyle modification for osteoporosis because it
directly stimulates bone formation and reduces fracture risk. Increasing calcium beyond recommended levels
does not provide additional benefit and may increase renal stone risk. Avoiding sun exposure would reduce
vitamin D synthesis, worsening osteoporosis. Passive range-of-motion exercises do not provide the
mechanical loading needed for bone health.
NRNR
601
601
Midterm
Midterm
-- 2026/2027
-- 2026/2027| Passing
| Passing
Score:
Score:
80%
80%| Page
| Page
3 of
3 ?
, Q4 Question 4 of 75
A 38-year-old woman presents for a well-woman exam. She is sexually active with a male
partner, uses condoms inconsistently, and has never been tested for HIV. According to
current screening guidelines, what is the most appropriate recommendation?
A. One-time opt-out HIV screening regardless of identified risk factors
B. HIV testing only if she reports high-risk sexual behaviors
C. Annual HIV screening with written informed consent
D. Defer HIV testing until she becomes pregnant
Correct Answer: A
Rationale:
The USPSTF and CDC recommend one-time opt-out HIV screening for all individuals aged 15-65 regardless
of disclosed risk factors, making option A correct. Requiring self-identified high-risk behavior misses many
undiagnosed cases. Annual testing is recommended only for those with ongoing risk, not universal screening.
Deferring until pregnancy would delay diagnosis and miss opportunities for early treatment.
Q5 Question 5 of 75
A 55-year-old man with a 30-pack-year smoking history quit smoking 8 months ago. He is
motivated to maintain abstinence and asks about strategies to prevent relapse. Which
evidence-based approach is most effective for sustained tobacco cessation in this patient?
A. Prescribing varenicline and scheduling regular follow-up counseling sessions
B. Recommending he switch to nicotine-free herbal cigarettes for 3 months
C. Advising complete avoidance of all social situations where others smoke
D. Suggesting he use an electronic cigarette whenever cravings occur
Correct Answer: A
Rationale:
Varenicline combined with behavioral counseling is the most evidence-based strategy for sustained smoking
cessation, with the highest quit rates in clinical trials. Herbal cigarettes maintain the behavioral habit without
addressing nicotine dependence. Social isolation is not a sustainable or recommended strategy. Electronic
cigarettes are not FDA-approved for cessation and carry their own health risks.
NRNR
601
601
Midterm
Midterm
-- 2026/2027
-- 2026/2027| Passing
| Passing
Score:
Score:
80%
80%| Page
| Page
4 of
4 ?
NR 601 Midterm Exam
Study Guide Weeks 1-4
Official Practice Exam -- 2026/2027 Edition
75 90 80% Multiple Choice
Questions Minutes Passing Score Format
TABLE OF CONTENTS
Section 1: Health Promotion & Disease Prevention .............. Questions 1-15
Section 2: Clinical Assessment & Diagnostic Reasoning ....... Questions 16-30
Section 3: Acute & Episodic Condition Management ............. Questions 31-45
Section 4: Chronic Disease Management ........................ Questions 46-60
Section 5: Pharmacology & Evidence-Based Practice ............ Questions 61-75
EXAM INSTRUCTIONS
This practice exam contains 75 multiple-choice questions divided into five sections. You have 90 minutes to
complete the entire exam. A passing score of 80% (60 correct out of 75) is required. Each question has four
answer choices (A through D); select the single best answer. No points are deducted for incorrect responses, so it
is advantageous to answer every question. Read each scenario carefully before selecting your response. Review
the rationale provided after each answer to reinforce your understanding of key concepts covered in Weeks 1
through 4 of NR 601.
TIPS FOR SUCCESS
1. Read the entire scenario and all four options before selecting an answer.
2. Eliminate obviously incorrect choices first to improve your odds.
3. Pay close attention to age-specific and setting-specific clues in each scenario.
4. The rationale after each question explains why the correct answer is right and why a
top distractor is wrong -- use these to deepen your understanding.
5. Time management: aim to spend no more than 72 seconds per question on average.
NR 601 Midterm -- 2026/2027 | Passing Score: 80% | Page 1 of ?
,Section 1: Health Promotion & Disease Prevention | 2026/2027
Q1 Question 1 of 75
A 52-year-old African American man presents for an annual wellness visit. He has no
significant past medical history and takes no medications. His blood pressure is 128/82
mmHg, BMI is 27, and he reports no exercise routine. According to USPSTF guidelines,
which screening should be prioritized at this visit?
A. Prostate-specific antigen testing for prostate cancer
B. Lipid panel screening for cardiovascular risk assessment
C. Colonoscopy referral beginning at age 45
D. Annual low-dose CT scan for lung cancer
Correct Answer: B
Rationale:
The USPSTF recommends lipid panel screening for cardiovascular risk assessment in men aged 40-75,
especially with risk factors like elevated BMI and sedentary lifestyle. Prostate cancer screening requires
shared decision-making, not automatic prioritization. Colonoscopy at 45 is important but lipid screening
addresses more immediate modifiable risk. Low-dose CT requires a significant smoking history, which this
patient lacks.
NRNR
601
601
Midterm
Midterm
-- 2026/2027
-- 2026/2027| Passing
| Passing
Score:
Score:
80%
80%| Page
| Page
2 of
2 ?
,Q2 Question 2 of 75
A 45-year-old woman with a family history of breast cancer in her mother at age 48 asks
about mammography screening. She has no breast symptoms and clinical breast exam is
unremarkable. Which recommendation aligns with current USPSTF guidelines for this
patient?
A. Begin mammography screening now and repeat every two years
B. Defer mammography until age 50 because her personal risk is average
C. Begin annual mammography immediately and refer for genetic counseling
D. Recommend breast MRI instead of mammography for high-risk screening
Correct Answer: A
Rationale:
The USPSTF recommends biennial mammography starting at age 40 for average-risk women, and this patient
with a first-degree relative diagnosed before age 50 may benefit from earlier initiation. Deferring to 50 ignores
her family history. Annual mammography and genetic counseling are not first-line USPSTF recommendations
without additional risk factors. Breast MRI is reserved for very high-risk patients, such as BRCA carriers.
Q3 Question 3 of 75
A 60-year-old postmenopausal woman with a T-score of -2.7 at the femoral neck is
counseled about osteoporosis management. She has no fracture history and takes calcium
600 mg twice daily. Which lifestyle modification is most important to emphasize during this
visit?
A. Increasing dietary calcium intake to 2,000 mg per day from food sources alone
B. Weight-bearing and resistance exercise at least 3-4 times per week
C. Avoiding all sun exposure to reduce melanoma risk
D. Daily passive range-of-motion exercises for joint flexibility
Correct Answer: B
Rationale:
Weight-bearing and resistance exercise is the most critical lifestyle modification for osteoporosis because it
directly stimulates bone formation and reduces fracture risk. Increasing calcium beyond recommended levels
does not provide additional benefit and may increase renal stone risk. Avoiding sun exposure would reduce
vitamin D synthesis, worsening osteoporosis. Passive range-of-motion exercises do not provide the
mechanical loading needed for bone health.
NRNR
601
601
Midterm
Midterm
-- 2026/2027
-- 2026/2027| Passing
| Passing
Score:
Score:
80%
80%| Page
| Page
3 of
3 ?
, Q4 Question 4 of 75
A 38-year-old woman presents for a well-woman exam. She is sexually active with a male
partner, uses condoms inconsistently, and has never been tested for HIV. According to
current screening guidelines, what is the most appropriate recommendation?
A. One-time opt-out HIV screening regardless of identified risk factors
B. HIV testing only if she reports high-risk sexual behaviors
C. Annual HIV screening with written informed consent
D. Defer HIV testing until she becomes pregnant
Correct Answer: A
Rationale:
The USPSTF and CDC recommend one-time opt-out HIV screening for all individuals aged 15-65 regardless
of disclosed risk factors, making option A correct. Requiring self-identified high-risk behavior misses many
undiagnosed cases. Annual testing is recommended only for those with ongoing risk, not universal screening.
Deferring until pregnancy would delay diagnosis and miss opportunities for early treatment.
Q5 Question 5 of 75
A 55-year-old man with a 30-pack-year smoking history quit smoking 8 months ago. He is
motivated to maintain abstinence and asks about strategies to prevent relapse. Which
evidence-based approach is most effective for sustained tobacco cessation in this patient?
A. Prescribing varenicline and scheduling regular follow-up counseling sessions
B. Recommending he switch to nicotine-free herbal cigarettes for 3 months
C. Advising complete avoidance of all social situations where others smoke
D. Suggesting he use an electronic cigarette whenever cravings occur
Correct Answer: A
Rationale:
Varenicline combined with behavioral counseling is the most evidence-based strategy for sustained smoking
cessation, with the highest quit rates in clinical trials. Herbal cigarettes maintain the behavioral habit without
addressing nicotine dependence. Social isolation is not a sustainable or recommended strategy. Electronic
cigarettes are not FDA-approved for cessation and carry their own health risks.
NRNR
601
601
Midterm
Midterm
-- 2026/2027
-- 2026/2027| Passing
| Passing
Score:
Score:
80%
80%| Page
| Page
4 of
4 ?
