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A nurse is reviewing a client’s medication list and notes the use of lisinopril. Which
condition is this medication primarily used to treat?
A. Hyperthyroidism
B. Hypertension
C. Diabetes mellitus
D. Peptic ulcer disease
Answer: B. Hypertension
Rationale: Lisinopril is an ACE inhibitor commonly prescribed to lower blood pressure. It
works by inhibiting the conversion of angiotensin I to angiotensin II, leading to
vasodilation and reduced blood pressure.
A nurse is caring for a client taking hydrochlorothiazide. Which electrolyte imbalance is
most likely?
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hyponatremia
Answer: B. Hypokalemia
Rationale: Thiazide diuretics like hydrochlorothiazide increase potassium excretion,
placing the client at risk for hypokalemia.
A client is prescribed clonidine. What is the primary effect of this medication?
A. Increase heart rate
,B. Lower blood pressure
C. Increase blood glucose
D. Promote diuresis
Answer: B. Lower blood pressure
Rationale: Clonidine is a centrally acting alpha-agonist that reduces sympathetic
outflow, lowering blood pressure.
Which medication is a thrombolytic?
A. Alteplase
B. Heparin
C. Warfarin
D. Aspirin
Answer: A. Alteplase
Rationale: Alteplase dissolves clots by activating plasminogen to plasmin, making it a
thrombolytic agent.
A nurse should monitor for which side effect in a client taking vancomycin?
A. Hypoglycemia
B. Ototoxicity
C. Constipation
D. Bradycardia
Answer: B. Ototoxicity
Rationale: Vancomycin can cause hearing damage, especially at high doses or with
prolonged use.
Which medication is used to treat Parkinson’s disease?
A. Levodopa
B. Haloperidol
C. Phenytoin
, D. Diazepam
Answer: A. Levodopa
Rationale: Levodopa is converted to dopamine in the brain, helping to manage
symptoms of Parkinson’s disease.
A client taking allopurinol should be monitored for which condition?
A. Hyperglycemia
B. Gout attacks
C. Kidney stones
D. Hypertension
Answer: C. Kidney stones
Rationale: Allopurinol reduces uric acid levels but may increase risk of kidney stones if
hydration is inadequate.
Which medication is a macrolide antibiotic?
A. Azithromycin
B. Amoxicillin
C. Ciprofloxacin
D. Doxycycline
Answer: A. Azithromycin
Rationale: Azithromycin is a macrolide antibiotic that inhibits bacterial protein synthesis.
A nurse should instruct a client taking isoniazid to take which supplement?
A. Vitamin C
B. Vitamin B6
C. Vitamin D
D. Vitamin K
Answer: B. Vitamin B6
Rationale: Isoniazid can cause peripheral neuropathy, which is prevented with
pyridoxine (vitamin B6).
Which medication is used to treat hyperkalemia?
A. Sodium polystyrene sulfonate