COMMON DIAGNOSIS AND MANAGEMENT IN
ACUTE CARE MIDTERM COMPREHENSIVE
ASSESSMENT 2026 SOLVED QUESTIONS WITH
VERIFIED ANSWERS
◉ Incidence of mental illness-what factors are increasing the
incidence Answer: Psychological and sociological factors
Lifestyle factors such as a client's smoking status, diet, exercise,
history of medication adherence, or history of addiction should be
considered when prescribing psychotropic medications
◉ Adherence Answer: Persistence
-taking med over intended time period
Compliance
-taking med as prescribed
◉ left hemisphere Answer: -speech comprehension
-word recognition
-grammar
-sequential processing
-recognition of detail
,-conscious mental processing
◉ right hemisphere Answer: -prosody of speech
-emotional modulation
-visual-spatial skills
-recognition of facial expression
-music
-abstract mathematical skills
-holistic processing
-unconscious mental processing
◉ Pharmacokinetics Answer: the study of what happens to a drug
from the time of administration until the parent drug and all
metabolites leave the body
◉ CYP450 Answer: CYP450 enzymes in the gut wall or liver convert
drug substrate into a biotransformed product in the bloodstream,
responsible for degradating of a large # of psychotropic drugs
-Not all ind. have same genetic form of CYP450 enzymes, determined
with pharmacogenetic testing
*Most individuals have "normal" rates of drug metabolism from the
major CYP450 enzymes and are said to be "extensive metabolizers",
most drug doses are set for these individuals.
,*genetic variants of these enzymes can make poor metabolizers or
ultra rapid metabolizers
Five of the most important:
CYP450 1A2, 2B6, 2D6, 2C9, 2C19, and 3A4.
◉ ultra rapid metabolizers Answer: elevated enzyme activity
subtherapeutic drug levels
poor efficacy with standard doses
◉ genotyping Answer: the patient for pharmacogenomic use
-genes for these CYP450 enzymes can now be readily measured and
used to predict which patients might need to have dosage
adjustments
-measurement of genes for drug metabolism
◉ most common targets of psychotropic drugs Answer: G-protein
receptors
-Drug actions at these receptors occur in a spectrum, from full
agonist actions, to partial agonist actions, to antagonism, and even to
inverse agonism.
◉ Pharmacokinetics concepts Answer: absorption
, distribution
metabolism
excretion
◉ Flockhart Table Answer: drug interactions that are mediated by
cytochrome P450 enzymes
comprehensive list of drugs and the interactions related to the
cytochrome P450 system
◉ Neurotransmitters Answer: chemicals released by neurons to
send communication across synaptic clefts to other neurons
-impact human emotion and behavior
◉ Neurotransmission: Answer: the chemical transmission of
information between neurons and their target cells
-the chemicals, or neurotransmitters, are released from their
transport vesicles to bind with receptor sites to perform their duties,
which are excitatory or inhibitory
-neurotransmitter then either returned and stored for future use
(reuptake) or inactivated and dissolved by enzymes
-Types: Classic, Retrograde, Volume
ACUTE CARE MIDTERM COMPREHENSIVE
ASSESSMENT 2026 SOLVED QUESTIONS WITH
VERIFIED ANSWERS
◉ Incidence of mental illness-what factors are increasing the
incidence Answer: Psychological and sociological factors
Lifestyle factors such as a client's smoking status, diet, exercise,
history of medication adherence, or history of addiction should be
considered when prescribing psychotropic medications
◉ Adherence Answer: Persistence
-taking med over intended time period
Compliance
-taking med as prescribed
◉ left hemisphere Answer: -speech comprehension
-word recognition
-grammar
-sequential processing
-recognition of detail
,-conscious mental processing
◉ right hemisphere Answer: -prosody of speech
-emotional modulation
-visual-spatial skills
-recognition of facial expression
-music
-abstract mathematical skills
-holistic processing
-unconscious mental processing
◉ Pharmacokinetics Answer: the study of what happens to a drug
from the time of administration until the parent drug and all
metabolites leave the body
◉ CYP450 Answer: CYP450 enzymes in the gut wall or liver convert
drug substrate into a biotransformed product in the bloodstream,
responsible for degradating of a large # of psychotropic drugs
-Not all ind. have same genetic form of CYP450 enzymes, determined
with pharmacogenetic testing
*Most individuals have "normal" rates of drug metabolism from the
major CYP450 enzymes and are said to be "extensive metabolizers",
most drug doses are set for these individuals.
,*genetic variants of these enzymes can make poor metabolizers or
ultra rapid metabolizers
Five of the most important:
CYP450 1A2, 2B6, 2D6, 2C9, 2C19, and 3A4.
◉ ultra rapid metabolizers Answer: elevated enzyme activity
subtherapeutic drug levels
poor efficacy with standard doses
◉ genotyping Answer: the patient for pharmacogenomic use
-genes for these CYP450 enzymes can now be readily measured and
used to predict which patients might need to have dosage
adjustments
-measurement of genes for drug metabolism
◉ most common targets of psychotropic drugs Answer: G-protein
receptors
-Drug actions at these receptors occur in a spectrum, from full
agonist actions, to partial agonist actions, to antagonism, and even to
inverse agonism.
◉ Pharmacokinetics concepts Answer: absorption
, distribution
metabolism
excretion
◉ Flockhart Table Answer: drug interactions that are mediated by
cytochrome P450 enzymes
comprehensive list of drugs and the interactions related to the
cytochrome P450 system
◉ Neurotransmitters Answer: chemicals released by neurons to
send communication across synaptic clefts to other neurons
-impact human emotion and behavior
◉ Neurotransmission: Answer: the chemical transmission of
information between neurons and their target cells
-the chemicals, or neurotransmitters, are released from their
transport vesicles to bind with receptor sites to perform their duties,
which are excitatory or inhibitory
-neurotransmitter then either returned and stored for future use
(reuptake) or inactivated and dissolved by enzymes
-Types: Classic, Retrograde, Volume
