ANSWERS SURE A+
✔✔A patient came to the emergency room complaining of sever abdominal pain.
Laboratory analysis revealed high concentrations of the dibasic amino acids in the
urine. The patient's pain subsided a few hours later after he passed a kidney stone. The
most likely diagnosis for this patient is:
a) Hartnup
b) Cystinuria
c) Kwashiorkor
d) hyperammonemia
e) scurvy - ✔✔b
✔✔What percent of the circulating amino acids is contributed to protein synthesis?
a) 9
b) 10-25
c) 30-40
d) 45-55
e) 75 - ✔✔e
✔✔In humans, the major route of nitrogen transfer from amino acids into ammonia
involves which of the following pairs of enzymes?
a) glutamine synthetase and urease
b) transaminases and glutaminase
c) glutamate dehydrogenase and transaminases
d) amino acid oxidases and arginase
e) glutaminase and amino acid oxidases - ✔✔c
✔✔Where is urea synthesized?
a) brain and pancreas
b) bones and joints
c) stomach and duodenum
d) liver and kidneys - ✔✔d
✔✔The most branced-chain amino acids (i.g. valine, isoleucine, & leucine) are
metabolized in the liver but not in the skeletal muscle
True or False - ✔✔False
✔✔Human body turns over the total body protein at about 10-20% (300-400 g) each
day.
, True or False - ✔✔False
is ~1-2% (30-40 g)
✔✔A deficiency in which of the following amino acids will result in negative nitrogen
balance, even though the diet may contain a large amount of protein.
a) serine
b) glutamate
c) tryptophan
d) alanine
e) asparagine - ✔✔c
- tryptophan is also related to Kwashiorkor disease
✔✔Pellagra-like symptom may be induced by which of the following conditions.
a) incomplete dietary protein such as corn protein
b) inherited defects in neutral amino acid transporter
c) niacin deficiency
d) all of the above
e) none of the above - ✔✔d
✔✔How long does it take for a fasting state?
a) up to 12 hours after meal
b) up to 24 hours
c) up to 48 hours
d) up to 72 hours
e) up to one week - ✔✔c
✔✔How long do hepatic glycogen stores last before exhaustion is reached?
a) within 12 hours
b) within 24-36 hours
c) within 1 week
d) within 1 month - ✔✔b
✔✔Amino acids from muscle breakdown provide the chief substrate for which metabolic
process during fasting state?
a) glycolysis
b) gluconeogenesis
c) glygenesis