, NU 636 QUIZ 6 | QUESTIONS AND
ANSWERS | 2026 UPDATE | 100%
CORRECT.
SECTION 1: ALLERGIC RHINITIS & INTRANASAL AGENTS
Q1. Intranasal antihistamines can be used for the treatment of
allergic rhinitis. Adverse effects associated with intranasal
antihistamine include all of the following EXCEPT:
A. Bitter taste
B. Dry mouth
C. Flatulence
C. Headache
Correct Answer: C. Flatulence
Rationale: Intranasal antihistamines (such as azelastine and olopatadine) are
effective for allergic rhinitis. Common adverse effects include bitter taste
(due to postnasal drip), dry mouth, headache, somnolence, and nasal
irritation. Flatulence is not associated with intranasal administration and is
not a recognized adverse effect of this route of administration.
Q2. Second-generation antihistamines such as Zyrtec (cetirizine)
and Claritin (loratadine) are advantageous secondary to which of
the following?
A. They are more expensive than 1st generation drugs
B. They do not cross the blood-brain barrier (minimal CNS penetration)
C. They are less expensive than 1st generation drugs
D. They cross the blood-brain barrier