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TCU MICROBIOLOGY EXAM 3 JONES QUESTIONS & ANSWERS

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TCU MICROBIOLOGY EXAM 3 JONES QUESTIONS & ANSWERS

Institution
TCU
Course
TCU

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Agglutination


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The clumping of small epitopes that can;t be visualized by phagocytes into
a bigger molecule & can be recognized in the spleen is a result of what
antibody function?

,Memory


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Ability to, if ever a specific pathogen was encountered again, to make a
quicker immune response due to already having been exposed




Germinal centers of Lymph nodes


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A lot of B cell replication occurs here




Klebsiella Pneumonia Pathogen & virulence factors


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-caused by Klebsiella pneumoniae (gram - rods, capsule gives colonies
mucoid appearance)
-virulence factors include capsule and release of endotoxin when cells die
leading to shock




Axenic


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, not contaminated by or associated with any foreign organisms; used in
reference to pure cultures of microorganisms or to germ-free animals




1


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How many epitopes does a single BCR receptor recognize?




5


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How many classes of antibodies are there?




Variable regions of heavy and light chains


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What part of the BCR has the ability to form different combinations and
hone in on the exact molecular shape




Legionnaire's Disease Pathogen & Virulence Factors


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, -most cases caused by Legionella pneumophila
-aerobic, slender, pleomorphic, gram -
-grown on Buffered Charcoal yeast Extract Agar (needs iron salts and
cysteine)




Lower respiratory system


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-organs are usually axenic (free of contaminants)
-bacterial infection of LRS can cause life-threatening illness




Klebsiella Pneumonia Pathogenesis & Epidemiology


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-leading cause of nosocomial acquired pneumonias
-immunocompromised individuals at greatest risk for infection




Clonal Selection of B cells


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-B cell attaches via BCR to and phagocytize a complimentary antigen
-B cells display pathogen's epitope with MHC 2 proteins
-B cells activate for humoral response

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