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CORE DOMAINS
Cardiovascular Critical Care
Pulmonary and Mechanical Ventilation Management
Neurological Critical Care
Renal and Electrolyte Balance Disorders
Endocrine and Metabolic Emergencies
Multisystem Organ Failure
Pharmacology in Critical Care
Hemodynamic Monitoring and Interpretation
Infection Control and Sepsis Management
Ethical and Legal Issues in Critical Care Nursing
INTRODUCTION
The Adult CCRN exam is designed to evaluate the critical thinking, clinical judgment, and
advanced nursing knowledge required to care for acutely and critically ill adult patients. It
,assesses the nurse’s ability to interpret complex patient data, manage life-threatening
conditions, and apply evidence-based interventions in high-acuity environments such as
intensive care units. The exam uses multiple-choice and scenario-based questions to
reflect real-world decision-making, prioritization, and clinical reasoning. Candidates must
demonstrate competence in cardiovascular, respiratory, neurological, renal, and
multisystem management, as well as pharmacology, ethics, and professional standards in
critical care practice.*
SECTION ONE: QUESTIONS 1–50
Question 1
A patient in septic shock has a mean arterial pressure (MAP) of 55 mmHg despite fluid
resuscitation. What is the priority intervention?
A. Administer diuretics
B. Start vasopressor therapy
C. Restrict oxygen therapy
D. Encourage oral fluids
🟢 Correct Answer: B. Start vasopressor therapy
,🔴 Explanation: Vasopressors such as norepinephrine are indicated when hypotension
persists after adequate fluid resuscitation to maintain organ perfusion.
Question 2
Which ECG finding is most indicative of acute myocardial infarction?
A. Peaked T waves
B. ST-segment elevation
C. Shortened PR interval
D. U waves
🟢 Correct Answer: B. ST-segment elevation
🔴 Explanation: ST-segment elevation indicates acute myocardial injury and is a hallmark
of STEMI requiring immediate intervention.
Question 3
A patient on mechanical ventilation has high peak airway pressures. What is the first
action?
, A. Increase tidal volume
B. Suction the airway
C. Decrease FiO₂
D. Administer diuretics
🟢 Correct Answer: B. Suction the airway
🔴 Explanation: High peak pressures are commonly caused by airway obstruction such as
secretions, requiring immediate suctioning.
Question 4
Which sign is most consistent with increased intracranial pressure?
A. Bradycardia and widened pulse pressure
B. Tachycardia and hypotension
C. Hyperactive bowel sounds
D. Fever and chills
🟢 Correct Answer: A. Bradycardia and widened pulse pressure
🔴 Explanation: Cushing’s triad (bradycardia, hypertension with widened pulse pressure,
irregular respirations) indicates increased ICP.