TestBank
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ForEvolutionaryAnalysis5thEditionBy JonC. Herron; Scott
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Freeman978032161667 Chapter1-20CompleteGuide.
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Evolutionary Analysis 5th Edition by Herron Jon; Freeman Scott ISBN 9780321998378 Chapter
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1-20
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Chapter 1 A Case for Evolutionary Thinking: Understanding HIV
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1) In which of the following regions has AIDS killed the largest number of individuals?
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A) India
B) Sub-Saharan Africa v
C) United States v
D) China
E) United Kingdom v
Answer: B
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Section: 1.1
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Skill: Knowledge/Comprehension
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2) The HIV virus contains all of the following components except
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A) integrase
B) double-stranded RNA v
C) single-stranded RNA v
D) reverse transcriptase v
E) protease
Answer: B
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Section:
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v1.1
Skill: Knowledge/Comprehension
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3) The acronym HIV stands for which of the following?
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A) human intercellular virus v v
B) human immune virus v v
C) human immunodeficiency virus v v
D) human immunity virus v v
E) human immunodeficiency vector
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Answer: C
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Section: 1.1 v
Skill: Knowledge/Comprehension
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4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
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A) RNA polymerase v
B) reverse transcriptase v
C) DNA polymerase v
D) reverse integrase v
E) RNAduplicase v
Answer: B
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Section: 1.1
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1
,Skill: Knowledge/Comprehension
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2
, 5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On what
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type of cells are these proteins typically observed?
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A) plasma cells v
B) dendritic cells v
C) effector helper T cells v v v
D) memory helper T cells v v v
E) both C and D v v v
Answer: E
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Section: 1.1
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Skill: Knowledge/Comprehension
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6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the blood
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drops below what concentration?
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A) 2,000 cells per cubic millimeter
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B) 1,000 cells per cubic millimeter
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C) 500 cells per cubic millimeter
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D) 200 cells per cubic millimeter
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E) No CD4 T cells are observed.
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Answer: D
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Section: 1.1 v
Skill: Knowledge/Comprehension
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7) Which of the following drug categories are used to treat HIV infections?
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A) integrase inhibitors v
B) protease inhibitors v
C) reverse transcriptase inhibitors v v
D) DNAse inhibitors v
E) fusion inhibitors v
Answer: D
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Section: 1.2
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Skill: Knowledge/Comprehension
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8) Coreceptor inhibitors block HIV infection by preventing which of the following?
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A) binding of the HIV virion onto the plasma membrane
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B) binding of the HIV virion onto the CCR5 receptor
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C) binding of the HIV virion onto the gp120 protein
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D) degrading the coreceptor so the virion cannot attach v v v v v v v
E) binding of the HIV virion onto the CD4 receptor
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Answer: B
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Section: 1.2 v
Skill: Application/Analysis
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9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
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A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell
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B) does not appear on the surface of CD4 T cells
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C) appears on the surface of the CD4 T cells and inactivates the virion upon binding
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D) interferes with binding of the virion to the CD4 receptor protein
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