COMPLETE ACTUAL TEST WITH REAL QUESTIONS AND CORRECT
ANSWERS (100% CORRECT VERIFIED SOLUTION) NEWEST
UPDATED VERSION |GUARANTEED PASS.2026-2027 McMaster
University
What happens prior to mitosis?
chromosomes must be duplicated and condensed, produce sister
chromatids that will eventually separate and move to 2 different cells
Describe prophase
chromosomes condense, centrosomes radiate microtubules and
migrate to opposite poles
Describe prometaphase
microtubules of the mitotic spindle attach to chromosomes, because
the nuclear envelope is beginning to break down
Describe metaphase
chromosomes align in the center of the cell at the metaphase plate
,Describe anaphase
sister chromatids (which become individual chromosomes when the
centromere splits) separate and travel to opposite poles
Describe telophase
nuclear envelope reforms and chromosomes decondense
Describe cytokinesis
division of the parent cell into 2 daughter cells, division of the
cytoplasm
and therefore the cell, form contractile ring which displays cleavage
furrow
, Tim Hunt and mitosis promoting factor from G2 to M phase
Tim hunt measured protein level changes of dividing sea urchin
embryos.
added radioactive methionine to eggs, took samples every 10 min
and used gel electrophoresis to see protein changes. most protein
bands came back darker each time, one band oscillated intensity
with each division- named the protein cyclin
Cyclin proteins
mitosis promoting factor between phases G2 and M consists of
cyclin proteins and cyclin-dependent kinases.
What are kinases?
Kinases are enzymes that activate or inactivate other proteins by
phosphorylating key amino acids on the target protein
G1/S cyclin-CDK complex
transition from G1 to S phase and preps DNA for replication
S-cyclin-CDK complex
initiates DNA synthesis